Gene: FLT3 ×
Source: INFERRED ×
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1057519762
rs1057519762
FLT3
G 0.700 GeneticVariation CLINVAR Reversal of acquired drug resistance in FLT3-mutated acute myeloid leukemia cells via distinct drug combination strategies. 24619500

2014
dbSNP: rs1057519765
rs1057519765
FLT3
A 0.700 GeneticVariation CLINVAR Reversal of acquired drug resistance in FLT3-mutated acute myeloid leukemia cells via distinct drug combination strategies. 24619500

2014
dbSNP: rs1057519767
rs1057519767
FLT3
C 0.700 GeneticVariation CLINVAR Reversal of acquired drug resistance in FLT3-mutated acute myeloid leukemia cells via distinct drug combination strategies. 24619500

2014
dbSNP: rs1057519768
rs1057519768
FLT3
C 0.700 GeneticVariation CLINVAR Reversal of acquired drug resistance in FLT3-mutated acute myeloid leukemia cells via distinct drug combination strategies. 24619500

2014
dbSNP: rs1057519769
rs1057519769
FLT3
A 0.700 GeneticVariation CLINVAR Reversal of acquired drug resistance in FLT3-mutated acute myeloid leukemia cells via distinct drug combination strategies. 24619500

2014
dbSNP: rs121909646
rs121909646
FLT3
A 0.700 CausalMutation CLINVAR Prospective enterprise-level molecular genotyping of a cohort of cancer patients. 25157968

2014
dbSNP: rs121913486
rs121913486
FLT3
T 0.700 GeneticVariation CLINVAR Prospective enterprise-level molecular genotyping of a cohort of cancer patients. 25157968

2014
dbSNP: rs121913490
rs121913490
FLT3
C 0.700 GeneticVariation CLINVAR Prospective enterprise-level molecular genotyping of a cohort of cancer patients. 25157968

2014
dbSNP: rs121913491
rs121913491
FLT3
C 0.700 GeneticVariation CLINVAR Prospective enterprise-level molecular genotyping of a cohort of cancer patients. 25157968

2014
dbSNP: rs1057519726
rs1057519726
FLT3
G 0.700 CausalMutation CLINVAR The importance of relative mutant level for evaluating impact on outcome of KIT, FLT3 and CBL mutations in core-binding factor acute myeloid leukemia. 23783394

2013
dbSNP: rs1057519726
rs1057519726
FLT3
G 0.700 CausalMutation CLINVAR Mutational landscape of AML with normal cytogenetics: biological and clinical implications. 23261068

2013
dbSNP: rs1057519726
rs1057519726
FLT3
G 0.700 CausalMutation CLINVAR Prospective evaluation of gene mutations and minimal residual disease in patients with core binding factor acute myeloid leukemia. 23321257

2013
dbSNP: rs1057519726
rs1057519726
FLT3
G 0.700 CausalMutation CLINVAR The role of kinase inhibitors in the treatment of patients with acute myeloid leukemia. 23714533

2013
dbSNP: rs1057519762
rs1057519762
FLT3
G 0.700 GeneticVariation CLINVAR Activity of ponatinib against clinically-relevant AC220-resistant kinase domain mutants of FLT3-ITD. 23430109

2013
dbSNP: rs1057519765
rs1057519765
FLT3
A 0.700 GeneticVariation CLINVAR Activity of ponatinib against clinically-relevant AC220-resistant kinase domain mutants of FLT3-ITD. 23430109

2013
dbSNP: rs1057519767
rs1057519767
FLT3
C 0.700 GeneticVariation CLINVAR Activity of ponatinib against clinically-relevant AC220-resistant kinase domain mutants of FLT3-ITD. 23430109

2013
dbSNP: rs1057519768
rs1057519768
FLT3
C 0.700 GeneticVariation CLINVAR Activity of ponatinib against clinically-relevant AC220-resistant kinase domain mutants of FLT3-ITD. 23430109

2013
dbSNP: rs1057519769
rs1057519769
FLT3
A 0.700 GeneticVariation CLINVAR Activity of ponatinib against clinically-relevant AC220-resistant kinase domain mutants of FLT3-ITD. 23430109

2013
dbSNP: rs121909646
rs121909646
FLT3
G 0.700 CausalMutation CLINVAR The role of kinase inhibitors in the treatment of patients with acute myeloid leukemia. 23714533

2013
dbSNP: rs121909646
rs121909646
FLT3
A 0.700 CausalMutation CLINVAR The role of kinase inhibitors in the treatment of patients with acute myeloid leukemia. 23714533

2013
dbSNP: rs121909646
rs121909646
FLT3
G 0.700 CausalMutation CLINVAR Mutational landscape of AML with normal cytogenetics: biological and clinical implications. 23261068

2013
dbSNP: rs121909646
rs121909646
FLT3
G 0.700 CausalMutation CLINVAR Prospective evaluation of gene mutations and minimal residual disease in patients with core binding factor acute myeloid leukemia. 23321257

2013
dbSNP: rs121909646
rs121909646
FLT3
A 0.700 CausalMutation CLINVAR Crenolanib is active against models of drug-resistant FLT3-ITD-positive acute myeloid leukemia. 24046014

2013
dbSNP: rs121909646
rs121909646
FLT3
A 0.700 CausalMutation CLINVAR The importance of relative mutant level for evaluating impact on outcome of KIT, FLT3 and CBL mutations in core-binding factor acute myeloid leukemia. 23783394

2013
dbSNP: rs121909646
rs121909646
FLT3
A 0.700 CausalMutation CLINVAR Mutational landscape of AML with normal cytogenetics: biological and clinical implications. 23261068

2013