|
rs1267969615
|
|
|
0.010 |
GeneticVariation |
BEFREE |
There was no association between genetic polymorphism of ACE, AGT M235T and AGTR1 A1166C and susceptibility to lupus nephritis, nor histological activity and chronicity indices in renal biopsy among the patients studied.
|
16047641 |
2005 |
|
rs699
|
|
|
0.010 |
GeneticVariation |
BEFREE |
There was no association between genetic polymorphism of ACE, AGT M235T and AGTR1 A1166C and susceptibility to lupus nephritis, nor histological activity and chronicity indices in renal biopsy among the patients studied.
|
16047641 |
2005 |
|
rs352140
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Both rs352139 (p=0.040, OR: 0.713, 95%CI: 0.516-0.985) and rs352140 (p=0.048, OR: 0.723, 95%CI: 0.525-0.997) were associated with LN in dominant model.
|
20497632 |
2010 |
|
rs352139
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Both rs352139 (p=0.040, OR: 0.713, 95%CI: 0.516-0.985) and rs352140 (p=0.048, OR: 0.723, 95%CI: 0.525-0.997) were associated with LN in dominant model.
|
20497632 |
2010 |
|
rs2004640
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The results suggested that the rs2004640 T allele was associated with susceptibility to lupus nephritis and that the IRF5 polymorphism analyzed did not seem to be implicated in the pathology and clinical manifestation of lupus nephritis in the Chinese population.
|
21040166 |
2010 |
|
rs2246614
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Additionally, rs4963128 and rs2246614 were correlated with a variety of clinical subphenotypes, such as lupus nephritis, arthritis, and the production of anti-SSA/B autoantibodies, despite a lack of significant association between these two SNPs and SLE disease susceptibility in general.
|
21167895 |
2011 |
|
rs11981433
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We found no association of PON2 SNPs with SLE risk but modest associations were observed with lupus nephritis (rs11981433, rs17876205, rs17876183) and immunologic disorder (rs11981433) in SLE patients (P = 0.013 to 0.042).
|
21223581 |
2011 |
|
rs2157257
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Multiple peaks of association exceeding a Bonferroni corrected P-value of P < 2.03 × 10(-3) were observed between LN and MYH9 in EAs (N = 4620), with the most pronounced association at rs2157257 (P = 4.7 × 10(-4), odds ratio (OR) = 1.205).
|
22189356 |
2012 |
|
rs2298804
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Although we did not find any significant correlation between the rs2298804 and the incidence of lupus nephritis, rs2298804 seemed to protect against proteinunia, fever and hypocomplementaemia in patients with SLE, but appeared to be a risk factor for photosensitivity and vasculitis.
|
23621092 |
2013 |
|
rs7708392
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Comparing cases of systemic lupus erythematosus with nephritis and cases of systemic lupus erythematosus without nephritis revealed strong associations with lupus nephritis at rs7708392 in European Americans and rs4958881 in African Americans.
|
23970121 |
2013 |
|
rs4958881
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Comparing cases of systemic lupus erythematosus with nephritis and cases of systemic lupus erythematosus without nephritis revealed strong associations with lupus nephritis at rs7708392 in European Americans and rs4958881 in African Americans.
|
23970121 |
2013 |
|
rs396991
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We genotyped FcγRIIIa-158V/F (rs396991) using a pyro-sequencing assay (PSQ 96MA) in a total of 732 individuals with SLE (390 lupus nephritis and 342 non-lupus nephritis) and 886 controls.
|
24131500 |
2013 |
|
rs6897932
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Moreover, association studies were also performed contraposing the relationship between the SNP rs6897932 C/T and lupus nephritis as well as 10 clinical features of SLE; however, no significant association signal was found regarding the distribution of allele and genotype frequencies between SLE patients positive and negative for the presence of 11 sub-phenotypes.
|
24242875 |
2014 |
|
rs11889341
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In the case-control analysis of cohort I, four highly linked SNPs in STAT4 were associated with lupus nephritis with genome wide significance with p = 3.7 × 10(-9), OR 2.20 for the best SNP rs11889341.
|
24386384 |
2013 |
|
rs10127939
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The low-binding haplotypes formed by 66L/R/H and 176F confer enhanced risk of lupus nephritis in African Americans.
|
24782186 |
2014 |
|
rs1364989
|
|
T |
0.700 |
GeneticVariation |
GWASCAT |
Lupus nephritis susceptibility loci in women with systemic lupus erythematosus.
|
24925725 |
2014 |
|
rs2647012
|
|
|
0.700 |
GeneticVariation |
GWASCAT |
Lupus nephritis susceptibility loci in women with systemic lupus erythematosus.
|
24925725 |
2014 |
|
rs274068
|
|
C |
0.700 |
GeneticVariation |
GWASCAT |
Lupus nephritis susceptibility loci in women with systemic lupus erythematosus.
|
24925725 |
2014 |
|
rs601162
|
|
A |
0.700 |
GeneticVariation |
GWASCAT |
Lupus nephritis susceptibility loci in women with systemic lupus erythematosus.
|
24925725 |
2014 |
|
rs7773456
|
|
|
0.700 |
GeneticVariation |
GWASCAT |
Lupus nephritis susceptibility loci in women with systemic lupus erythematosus.
|
24925725 |
2014 |
|
rs7834765
|
|
T |
0.700 |
GeneticVariation |
GWASCAT |
Lupus nephritis susceptibility loci in women with systemic lupus erythematosus.
|
24925725 |
2014 |
|
rs8012283
|
|
G |
0.700 |
GeneticVariation |
GWASCAT |
Lupus nephritis susceptibility loci in women with systemic lupus erythematosus.
|
24925725 |
2014 |
|
rs1143679
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Our meta-analyses confirm that the ITGAM rs1143679 polymorphism is associated with SLE susceptibility in different ethnic groups and demonstrate that the polymorphism is associated with LN in European.
|
25315704 |
2015 |
|
rs172378
|
|
|
0.010 |
GeneticVariation |
BEFREE |
These results support the implication of the G allele in rs172378 as a risk factor for lupus nephritis in a homozygous status, at least for a Bulgarian population.
|
25326229 |
2015 |
|
rs28940579
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The prevalence of four MEFV gene mutations (M694V, M680I, V726A and E148Q) was investigated in 114 SLE patients and effect on disease severity was analyzed in patients with biopsy-proven SLE nephritis.
|
25413357 |
2015 |