Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs11057864
rs11057864
0.700 GeneticVariation GWASCAT Response to Intravenous Cyclophosphamide Treatment for Lupus Nephritis Associated with Polymorphisms in the FCGR2B-FCRLA Locus. 26980576

2016

dbSNP: rs1108131
rs1108131
0.700 GeneticVariation GWASCAT Response to Intravenous Cyclophosphamide Treatment for Lupus Nephritis Associated with Polymorphisms in the FCGR2B-FCRLA Locus. 26980576

2016

dbSNP: rs2647012
rs2647012
0.700 GeneticVariation GWASCAT Lupus nephritis susceptibility loci in women with systemic lupus erythematosus. 24925725

2014

dbSNP: rs6697139
rs6697139
0.700 GeneticVariation GWASCAT Response to Intravenous Cyclophosphamide Treatment for Lupus Nephritis Associated with Polymorphisms in the FCGR2B-FCRLA Locus. 26980576

2016

dbSNP: rs7692514
rs7692514
0.700 GeneticVariation GWASCAT Response to Intravenous Cyclophosphamide Treatment for Lupus Nephritis Associated with Polymorphisms in the FCGR2B-FCRLA Locus. 26980576

2016

dbSNP: rs7773456
rs7773456
0.700 GeneticVariation GWASCAT Lupus nephritis susceptibility loci in women with systemic lupus erythematosus. 24925725

2014

dbSNP: rs958476
rs958476
0.700 GeneticVariation GWASCAT Response to Intravenous Cyclophosphamide Treatment for Lupus Nephritis Associated with Polymorphisms in the FCGR2B-FCRLA Locus. 26980576

2016

dbSNP: rs1143679
rs1143679
0.020 GeneticVariation BEFREE Conclusion CD11b rs1143679 appears to be associated with risk for SLE in the Han Chinese population, and may play an important role in the development of lupus nephritis. 29207897

2018

dbSNP: rs1143679
rs1143679
0.020 GeneticVariation BEFREE Our meta-analyses confirm that the ITGAM rs1143679 polymorphism is associated with SLE susceptibility in different ethnic groups and demonstrate that the polymorphism is associated with LN in European. 25315704

2015

dbSNP: rs2910164
rs2910164
0.020 GeneticVariation BEFREE This is the first report documenting that the <i>miR-146a</i> rs2910164G/C and <i>miR-499</i> rs3746444 polymorphisms are associated with SLE susceptibility but not with LN. 29190882

2017

dbSNP: rs2910164
rs2910164
0.020 GeneticVariation BEFREE The objective of this study was to identify the association between genotypes of miR-146a rs2910164 and expression of TRAF6 as well as the risk of lupus nephritis (LN). 29754557

2017

dbSNP: rs352140
rs352140
0.020 GeneticVariation BEFREE Both rs352139 (p=0.040, OR: 0.713, 95%CI: 0.516-0.985) and rs352140 (p=0.048, OR: 0.723, 95%CI: 0.525-0.997) were associated with LN in dominant model. 20497632

2010

dbSNP: rs352140
rs352140
0.020 GeneticVariation BEFREE A significant genotypic and allelic association was revealed between TLR-9-rs352140 and both SLE and LN (P < 0·05). 28763101

2017

dbSNP: rs7708392
rs7708392
0.020 GeneticVariation BEFREE Our results suggested that TNIP1 SNP (rs7708392) might be associated with the LN</span> in Egyptian SLE patients. 29589214

2018

dbSNP: rs7708392
rs7708392
0.020 GeneticVariation BEFREE Comparing cases of systemic lupus erythematosus with nephritis and cases of systemic lupus erythematosus without nephritis revealed strong associations with lupus nephritis at rs7708392 in European Americans and rs4958881 in African Americans. 23970121

2013

dbSNP: rs10127939
rs10127939
0.010 GeneticVariation BEFREE The low-binding haplotypes formed by 66L/R/H and 176F confer enhanced risk of lupus nephritis in African Americans. 24782186

2014

dbSNP: rs1061170
rs1061170
CFH
0.010 GeneticVariation BEFREE There was a significantly higher ratio of CC/CT genotypes of rs1061170 in lupus nephritis patients with class III than in the other two classes (class III vs. class IV vs. class V: 21.0% vs. 9.7% vs. 9.4%; P = .044). 28403670

2017

dbSNP: rs11203368
rs11203368
0.010 GeneticVariation BEFREE Carriage of minor alleles of five other SNPs (rs11203366, rs11203367, rs874881, rs2240340, and rs11203368) was associated with increased occurrence of LN and hypertension. 30269634

2019

dbSNP: rs114580964
rs114580964
0.010 GeneticVariation BEFREE We discovered five independent risk variants for LN within the MHC region, including <i>HLA-DRβ1</i> amino acid 11 (<i>P</i><sub>omnibus</sub><0.001), <i>HLA-DQβ1</i> amino acid 45 (<i>P</i><0.001; odds ratio, 0.58; 95% confidence interval, 0.52 to 0.65), <i>HLA-A</i> amino acid 156 (<i>P</i><sub>omnibus</sub><0.001), <i>HLA-DPβ1</i> amino acid 76 (<i>P</i><sub>omnibus</sub><0.001), and a missense variant in <i>PRRC2A</i> (rs114580964; <i>P</i><0.001; odds ratio, 0.38; 95% confidence interval, 0.30 to 0.49) at genome-wide significance. 28754791

2017

dbSNP: rs117026326
rs117026326
0.010 GeneticVariation BEFREE Patients carrying genotype TT of rs117026326 had lower 24-hour urinary total protein (24 hours UTP, g/24 hours), 24-hour urinary protein level (g/L·24 hours), lower frequency of the proteinuria and lupus nephritis (LN). 31374066

2019

dbSNP: rs11889341
rs11889341
0.010 GeneticVariation BEFREE In the case-control analysis of cohort I, four highly linked SNPs in STAT4 were associated with lupus nephritis with genome wide significance with p = 3.7 × 10(-9), OR 2.20 for the best SNP rs11889341. 24386384

2013

dbSNP: rs11893826
rs11893826
0.010 GeneticVariation BEFREE A total of 111 patients with SLE (50 with SLE without nephritis, 55 with LN and 6 with simple urinary sediment abnormalities) and 62 healthy controls (HC) were genotyped for NCX1 rs11893826 (NCX1a) and rs434082 (NCX1b) and ADD2 rs4984 SNPs. 26045217

2015

dbSNP: rs11981433
rs11981433
0.010 GeneticVariation BEFREE We found no association of PON2 SNPs with SLE risk but modest associations were observed with lupus nephritis (rs11981433, rs17876205, rs17876183) and immunologic disorder (rs11981433) in SLE patients (P = 0.013 to 0.042). 21223581

2011

dbSNP: rs1267969615
rs1267969615
ACE
0.010 GeneticVariation BEFREE There was no association between genetic polymorphism of ACE, AGT M235T and AGTR1 A1166C and susceptibility to lupus nephritis, nor histological activity and chronicity indices in renal biopsy among the patients studied. 16047641

2005

dbSNP: rs1391441
rs1391441
0.010 GeneticVariation BEFREE Four trans-eSNPs were observed to be associated with susceptibility to LN (P < 0.05), including ANKRD50 rs17008504, AGA rs2271100, PAK7 rs6056923, and TET2 rs1391441, while seven other trans-eSNPs showed marginal significant associations (0.05 < P < 0.1). 26509176

2015