|
rs4401971
|
|
|
0.800 |
GeneticVariation |
GWASCAT |
Genome-wide association study in obsessive-compulsive disorder: results from the OCGAS.
|
24821223 |
2015 |
|
rs4401971
|
|
A |
0.800 |
GeneticVariation |
GWASDB |
Genome-wide association study in obsessive-compulsive disorder: results from the OCGAS.
|
24821223 |
2015 |
|
rs12504244
|
|
|
0.700 |
GeneticVariation |
GWASCAT |
Examination of the shared genetic basis of anorexia nervosa and obsessive-compulsive disorder.
|
30087453 |
2018 |
|
rs12536521
|
|
|
0.700 |
GeneticVariation |
GWASCAT |
Sex differences in the genetic architecture of obsessive-compulsive disorder.
|
30456828 |
2019 |
|
rs12635725
|
|
|
0.700 |
GeneticVariation |
GWASCAT |
Sex differences in the genetic architecture of obsessive-compulsive disorder.
|
30456828 |
2019 |
|
rs28696717
|
|
|
0.700 |
GeneticVariation |
GWASCAT |
Sex differences in the genetic architecture of obsessive-compulsive disorder.
|
30456828 |
2019 |
|
rs4785741
|
|
T |
0.700 |
GeneticVariation |
GWASCAT |
Polygenic risk score and heritability estimates reveals a genetic relationship between ASD and OCD.
|
28641744 |
2017 |
|
rs6109227
|
|
|
0.700 |
GeneticVariation |
GWASDB |
Genome-wide association study of obsessive-compulsive disorder.
|
22889921 |
2013 |
|
rs6131293
|
|
|
0.700 |
GeneticVariation |
GWASDB |
Genome-wide association study of obsessive-compulsive disorder.
|
22889921 |
2013 |
|
rs6131295
|
|
|
0.700 |
GeneticVariation |
GWASDB |
Genome-wide association study of obsessive-compulsive disorder.
|
22889921 |
2013 |
|
rs10491734
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The present study provided suggestive evidence that the rs10491734 was significantly associated with early-onset OCD in the Han Chinese population.
|
23564280 |
2013 |
|
rs10491734
|
|
|
0.020 |
GeneticVariation |
BEFREE |
This case-control study enrolled 578 obsessive-compulsive disorder (OCD) patients and 649 controls and genotyped rs10491734, rs2228622, rs301430 and rs301443 to replicate association of the SLC1A1 gene with OCD in ethnic Han Chinese.
|
23411042 |
2013 |
|
rs1000592
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The case-control analyses revealed a nominal significant association of the HTR3D variant rs1000592 (p.H52R) with OCD (p=0.029) which was also evident after combination of the case-control and the trio-results (p=0.024).
|
23928294 |
2014 |
|
rs10042486
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We concluded that among the HTR1A polymorphisms, only the association of rs10042486 CT genotype and OCD was statistically significant.
|
30232922 |
2019 |
|
rs10070190
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Five SNPs achieved 0.004 (the nominal p-value expected by chance), 3 with empirical significant p-values (rs10070190 (CDH9) p = 1 × 10(-3), rs4825476 (GRIA3) p = 4 × 10(-4), and rs1074815 (TPH2) p = 8 × 10(-4)) and 2 additional polymorphisms showing nominal significance (rs2834070 (OLIG2) p = 2 × 10(-3) and rs11783752 (SCL18A1) p = 3 × 10(-3)), were found to be related to both AN and OCD.
|
23337130 |
2013 |
|
rs11783752
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Five SNPs achieved 0.004 (the nominal p-value expected by chance), 3 with empirical significant p-values (rs10070190 (CDH9) p = 1 × 10(-3), rs4825476 (GRIA3) p = 4 × 10(-4), and rs1074815 (TPH2) p = 8 × 10(-4)) and 2 additional polymorphisms showing nominal significance (rs2834070 (OLIG2) p = 2 × 10(-3) and rs11783752 (SCL18A1) p = 3 × 10(-3)), were found to be related to both AN and OCD.
|
23337130 |
2013 |
|
rs17162912
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We attempt to replicate the GWAS finding by investigating the association of the DISP1 rs17162912 polymorphism with SRI response in our sample of 112 European Caucasian OCD patients.
|
29953682 |
2018 |
|
rs2097063
|
|
|
0.010 |
GeneticVariation |
BEFREE |
When the OCD group and controls were compared, no significant difference was found between COMT -287A/G (rs2097063), 5-HTTLPR I/D polymorphisms, and OCD.
|
25751280 |
2015 |
|
rs2834070
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Five SNPs achieved 0.004 (the nominal p-value expected by chance), 3 with empirical significant p-values (rs10070190 (CDH9) p = 1 × 10(-3), rs4825476 (GRIA3) p = 4 × 10(-4), and rs1074815 (TPH2) p = 8 × 10(-4)) and 2 additional polymorphisms showing nominal significance (rs2834070 (OLIG2) p = 2 × 10(-3) and rs11783752 (SCL18A1) p = 3 × 10(-3)), were found to be related to both AN and OCD.
|
23337130 |
2013 |
|
rs3933331
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In addition, another SNP correlating with SLC1A1 gene expression, rs3933331, was associated with an OCD-hoarding subphenotype as assessed by 2 independent, validated scales.
|
19349310 |
2009 |
|
rs4387163
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Three SNPs are most strongly associated with OCD: rs11854486 (P = 0.00005 [0.046 after adjustment for multiple tests]; genetic relative risk (GRR) = 11.1 homozygous and 1.6 heterozygous) and rs4625687 [P = 0.00007 (after adjustment = 0.06); GRR = 2.4] on 15q; and rs4387163 (P = 0.0002 (after adjustment = 0.08); GRR = 1.97) on 1q.
|
22095678 |
2012 |
|
rs4740788
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We also found that SNP rs4740788, located about 8.8 kb upstream of the gene, was associated with OCD in all families (P = 0.003) and in families with male affecteds (P = 0.002).
|
21445956 |
2011 |
|
rs2364841
|
|
|
0.700 |
GeneticVariation |
GWASCAT |
Sex differences in the genetic architecture of obsessive-compulsive disorder.
|
30456828 |
2019 |
|
rs165599
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A haplotype composed of three SNPs [rs2097603; rs4680 (158Val/Met); rs165599] representing the major linkage disequilibrium blocks in COMT and previously implicated in functional variation, was found to be associated with ADHD and OCD in 22q11.2DS individuals.
|
17949513 |
2008 |
|
rs2071592
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Given the importance of NFKBIL1 in the immunological response, the present study investigated the -62A/T polymorphism (rs2071592), located in the promoter region of its gene (NFKBIL1), as a genetic risk factor for the development of obsessive-compulsive disorder.
|
19578685 |
2009 |