|
rs12425791
|
|
|
0.890 |
GeneticVariation |
BEFREE |
This is a precedent study that found genetic variants of rs12425791 and rs11833579 on chromosome 12p13 are independent predictors of stroke-related mortality or stroke recurrence in patients with incident ischemic stroke in Taiwan.
|
22212150 |
2012 |
|
rs12425791
|
|
|
0.890 |
GeneticVariation |
BEFREE |
Our data suggest that rs12425791 on chromosome 12p13 is a genetic marker for atherothrombotic stroke in multiethnic population.
|
20448654 |
2010 |
|
rs12425791
|
|
|
0.890 |
GeneticVariation |
BEFREE |
Recent genome-wide association studies (GWAS) have identified two key SNPs (rs11833579 and rs12425791) on chromosome 12p13 that were significantly associated with stroke in Caucasians.
|
22938733 |
2012 |
|
rs12425791
|
|
|
0.890 |
GeneticVariation |
BEFREE |
Recent genome-wide association (GWA) studies have identified two intergenic single nucleotide polymorphisms (SNPs) (rs11833579 and rs12425791) on chromosome 12p13 and within 11 kb of the NINJ2 gene that were significantly associated with stroke in Caucasians.
|
21376321 |
2011 |
|
rs12425791
|
|
|
0.890 |
GeneticVariation |
BEFREE |
rs12425791 and rs11833579 were not associated with age of stroke onset (P = 0.786 and 0.340, respectively).
|
24995625 |
2014 |
|
rs12425791
|
|
|
0.890 |
GeneticVariation |
BEFREE |
These findings indicate that rs12425791 G>A polymorphism may be a low-penetrance susceptibility marker of stroke in Asian populations and further studies are warranted to verify this association.
|
26312640 |
2016 |
|
rs12425791
|
|
|
0.890 |
GeneticVariation |
BEFREE |
These results suggested that the rs12425791 and rs11833579 polymorphisms on Chromosome 12p13 may be associated with the risk of LAA stroke and might be used as candidate biomarkers for LAA stroke susceptibility.
|
26145198 |
2015 |
|
rs12425791
|
|
|
0.890 |
GeneticVariation |
BEFREE |
In 2009, a GWAS has confirmed that rs11833579 and rs12425791 near the NINJ2 gene could increase the stroke and ischemic stroke (IS) risk.
|
22795341 |
2012 |
|
rs12425791
|
|
|
0.890 |
GeneticVariation |
BEFREE |
A recent genome-wide association study (GWAS) identified two common polymorphisms (rs12425791 and rs11833579) on chromosome 12p13 that confer risk to stroke, particularly for large artery atherosclerotic (LAA) stroke.
|
26687183 |
2016 |
|
rs2107595
|
|
|
0.850 |
GeneticVariation |
BEFREE |
We further performed detailed plaque phenotyping and genotyping of rs2107595, the lead single-nucleotide polymorphism for large-vessel stroke, in carotid endarterectomy samples of 1858 subjects from the Athero-Express study.
|
25388417 |
2015 |
|
rs2107595
|
|
|
0.850 |
GeneticVariation |
BEFREE |
In HDAC9 SNP rs2107595 risk allele-positive LVAS patients, there were 155 genes differentially expressed compared to risk allele-negative patients (fold change > ;1.2;, p < 0.05).
|
29651704 |
2019 |
|
rs2107595
|
|
|
0.850 |
GeneticVariation |
BEFREE |
Results- Targeted resequencing of the <i>HDAC9</i> locus in patients with atherosclerotic stroke and controls supported candidacy of rs2107595 as the causative single nucleotide polymorphism.
|
31500558 |
2019 |
|
rs2107595
|
|
|
0.850 |
GeneticVariation |
BEFREE |
Apolipoprotein L1 (APOL1) rs73885319 (OR = 1.52; CI: 1.09-2.13, P-value = .013), rs2383207 in CDKN2A/CDKN2B (OR = 3.08; CI: 1.15-8.26, P -value = .026) and rs2107595 (OR = 1.70; CI: 1.12-2.60, P-value = .014) and rs28688791 (OR = 1.52; CI: 1.03-2.26, P-value = .036) in HDAC9 gene were associated with SVD stroke at 0.05 significance level.
|
28975602 |
2018 |
|
rs2107595
|
|
|
0.850 |
GeneticVariation |
GWASCAT |
Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes.
|
29531354 |
2018 |
|
rs2107595
|
|
|
0.850 |
GeneticVariation |
BEFREE |
Our results revealed statistically significant associations of the rs2107595 (T/C) polymorphism with an increased risk of stroke in the allele, codominant and dominant models.
|
28145521 |
2017 |
|
rs11984041
|
|
|
0.830 |
GeneticVariation |
BEFREE |
The variant rs556621 but not rs11984041 may increase susceptibility of LAA stroke in the Xinjiang Uyghur population.
|
25307434 |
2015 |
|
rs11984041
|
|
|
0.830 |
GeneticVariation |
BEFREE |
A recent Genome-Wide Association study (GWAS) identified rs11984041 on HDAC9 gene to be significantly associated with stroke in a Caucasian population.
|
23828597 |
2013 |
|
rs11984041
|
|
|
0.830 |
GeneticVariation |
BEFREE |
We identified a new association for large vessel stroke within HDAC9 (encoding histone deacetylase 9) on chromosome 7p21.1 (including further replication in an additional 735 affected individuals and 28,583 controls) (rs11984041; combined P = 1.87 × 10(-11); odds ratio (OR) = 1.42, 95% confidence interval (CI) = 1.28-1.57).
|
22306652 |
2012 |
|
rs2200733
|
|
|
0.820 |
GeneticVariation |
BEFREE |
The SNP rs2200733 on chromosome 4q25 is a risk factor for CE stroke related to AF only.
|
21574119 |
2011 |
|
rs2200733
|
|
|
0.820 |
GeneticVariation |
BEFREE |
Subsequently subgroup analysis indicated that both rs2200733 and rs10033464 conferred increased risk for cardioembolic stroke (CE str</span>oke) (for rs2200733, OR 1.38, 95 % CI 1.26-1.51; for rs10033464, OR 1.14, 95 % CI 1.02-1.26), while rs2200733 was marginal associated with non-CE stroke (OR 1.09, 95 % CI 1.02-1.16). our results demonstrated that two SNPs (rs2200733 and rs1003346) on chromosome 4q25 were limited to the stroke of cardioembolic etiology.
|
24065534 |
2013 |
|
rs2200733
|
|
|
0.820 |
GeneticVariation |
GWASDB |
Genome-wide association study identifies a variant in HDAC9 associated with large vessel ischemic stroke.
|
22306652 |
2012 |
|
rs556621
|
|
|
0.820 |
GeneticVariation |
BEFREE |
Smoking status, sex did not significantly influence the relationship between genotypes of rs556621 and risk of LAA st</span>roke (P <sub>interaction</sub> = 0.140, P <sub>interaction</sub> = 0.076).
|
27567922 |
2017 |
|
rs556621
|
|
|
0.820 |
GeneticVariation |
BEFREE |
The variant rs556621 but not rs11984041 may increase susceptibility of LAA stroke in the Xinjiang Uyghur population.
|
25307434 |
2015 |
|
rs1799963
|
|
|
0.810 |
GeneticVariation |
BEFREE |
In multinomial multivariate adjusted analysis, rs1799963 was exclusively associated with undetermined stroke (OR: 3.67; 95% CI: 1.52-8.85; p = 0.004).
|
25897999 |
2015 |
|
rs161802
|
|
|
0.800 |
GeneticVariation |
GWASCAT |
Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants.
|
24262325 |
2014 |