rs1003346
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Subsequently subgroup analysis indicated that both rs2200733 and rs10033464 conferred increased risk for cardioembolic stroke (CE stroke) (for rs2200733, OR 1.38, 95 % CI 1.26-1.51; for rs10033464, OR 1.14, 95 % CI 1.02-1.26), while rs2200733 was marginal associated with non-CE stroke (OR 1.09, 95 % CI 1.02-1.16). our results demonstrated that two SNPs (rs2200733 and rs1003346) on chromosome 4q25 were limited to the stroke of cardioembolic etiology.
|
24065534 |
2013 |
rs10033464
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Subsequently subgroup analysis indicated that both rs2200733 and rs1</span>0033464 conferred increased risk for cardioembolic stroke (CE stroke) (for rs2200733, OR 1.38, 95 % CI 1.26-1.51; for rs10033464, OR 1.14, 95 % CI 1.02-1.26), while rs2200733 was marginal associated with non-CE stroke (OR 1.09, 95 % CI 1.02-1.16). our results demonstrated that two SNPs (rs2200733 and rs1003346) on chromosome 4q25 were limited to the stroke of cardioembolic etiology.
|
24065534 |
2013 |
rs10089084
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Therefore, this study aimed to investigate the association between the occurrence of <i>TPH1, TPH2, KAT1, KAT2</i> and <i>IDO1</i> polymorphisms and the risk of stroke development.The following 10 polymorphisms of the genes encoding enzymes of the TRYCATs pathway were selected: c.804-7C > A (rs10488682), c.-1668T > A (rs623580), c.803+221C > A (rs1800532), c.-173A > T (rs1799913) - <i>TPH1</i>, c.-1449C > A (rs7963803), and c.-844G > T (rs4570625) - <i>TPH2</i>. c.*456G > A of <i>KAT1</i> (rs10988134), c.975-7T > C of <i>KAT2</i> (rs1480544), c.-1849C > A (rs3824259) and c. -1493G > C (rs10089084) of <i>IDO1</i>.
|
31817010 |
2019 |
rs1010
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The odds ratios for noncardioembolic stroke were 1.31 (90% CI 1.07-1.60) for rs3900940 in MYH15, 1.24 (90% CI 1.01-1.5) for rs20455 in KIF6, 1.21 (90% CI 0.99-1.49) for rs1010 in VAMP8, and 1.20 (90% CI 0.95-1.50) for rs10757274 on chromosome 9p21.
|
19752551 |
2009 |
rs10118757
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The G allele of rs10118757 was associated with an increased risk of stroke, with a per-allele OR of 1.31(95% CI, 1.04-1.65, p=0.025).
|
19427650 |
2009 |
rs10123021
|
|
|
0.700 |
GeneticVariation |
GWASDB |
Genetic mapping and exome sequencing identify 2 mutations associated with stroke protection in pediatric patients with sickle cell anemia.
|
23422753 |
2013 |
rs1035543
|
|
|
0.700 |
GeneticVariation |
GWASDB |
Genetic mapping and exome sequencing identify 2 mutations associated with stroke protection in pediatric patients with sickle cell anemia.
|
23422753 |
2013 |
rs10401969
|
|
|
0.700 |
GeneticVariation |
GWASCAT |
Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.
|
27790247 |
2016 |
rs10414398
|
|
|
0.700 |
GeneticVariation |
GWASDB |
Genetic mapping and exome sequencing identify 2 mutations associated with stroke protection in pediatric patients with sickle cell anemia.
|
23422753 |
2013 |
rs1041740
|
|
|
0.010 |
GeneticVariation |
BEFREE |
However, three variants were associated with increased risk of death from cardiovascular causes (sudden death, fatal myocardial infarction or stroke) during the follow-up: rs9974610 (HR 0.64, 95% CI 0.46-0.88, p=0.005), rs10432782 (HR 1.71, 95% CI 1.16-2.48, p=0.007) and rs1041740 (HR 1.78, 95% CI 1.10-2.78, p=0.02).
|
22608880 |
2012 |
rs10423928
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Moreover, the common variant rs10423928 in the GIPR gene is associated with increased risk of stroke in patients with type 2 diabetes.
|
26395740 |
2016 |
rs1042522
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Moreover, we have previously described that the human Tp53 Arg72Pro single nucleotide polymorphism (SNP) controls susceptibility to ischemia-induced neuronal apoptosis and governs the functional outcome of patients after stroke.
|
29687302 |
2019 |
rs1042522
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Interestingly, the Arg72Pro SNP in TP53, the gene encoding tumor suppressor p53, was recently revealed a biomarker of poor prognosis in stroke due to its ability to modulate neuronal apoptotic death.
|
22695677 |
2013 |
rs1042522
|
|
|
0.030 |
GeneticVariation |
BEFREE |
The human Tp53 Arg72Pro polymorphism explains different functional prognosis in stroke.
|
21357744 |
2011 |
rs1042579
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Thrombomodulin Ala455Val Polymorphism and the risk of cerebral infarction in a biracial population: the Stroke Prevention in Young Women Study.
|
15574195 |
2004 |
rs1042713
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A recessive model demonstrated a significant association between Arg16/Gly and: absolute supine and upright HR; HUT-induced change in cardiac index (CI), stroke index (SI) and systemic vascular resistance (SVR); and supine and upright norepinephrine values.
|
21807569 |
2011 |
rs1042714
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Carriers of the Glu allele of the Gln27Glu polymorphism showed an elevated systolic and diastolic BP, mean arterial pressure, total peripheral resistance index, and a lower stroke volume in EA.
|
12441217 |
2002 |
rs1042714
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The aim of this replication study was to confirm our previous findings of associations between the TNF(-308) G/A, IL4R 503 S/P, and ADRB2 27 Q/E polymorphisms and large vessel stroke risk.
|
17600229 |
2007 |
rs10432782
|
|
|
0.010 |
GeneticVariation |
BEFREE |
However, three variants were associated with increased risk of death from cardiovascular causes (sudden death, fatal myocardial infarction or stroke) during the follow-up: rs9974610 (HR 0.64, 95% CI 0.46-0.88, p=0.005), rs10432782 (HR 1.71, 95% CI 1.16-2.48, p=0.007) and rs1041740 (HR 1.78, 95% CI 1.10-2.78, p=0.02).
|
22608880 |
2012 |
rs10435816
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Subgroup analysis indicated that rs10435816 (additive model: OR=0.61, 95%CI, 0.41-0.89; recessive model: OR=0.56, 95%CI, 0.40-0.80), rs7025417 (additive model: OR=0.57, 95%CI, 0.39-0.83), rs11792633 (additive model: OR=0.66, 95%CI, 0.46-0.95; recessive model: OR=0.67, 95%CI, 0.49-0.93), and rs7044343 (additive model: OR=0.69, 95%CI, 0.48-0.97; recessive model: OR=0.67, 95%CI, 0.49-0.91) were associated with a decreased risk of large-artery atherosclerosis stroke after adjustment of confounding factors.
|
31660817 |
2019 |
rs1043994
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Altogether, 134 Finnish CADASIL patients with p.Arg133Cys mutation were analysed for possible associations between the apolipoprotein E (APOE) genotype, angiotensinogen (AGT) p.Met268Thr polymorphism or neutral p.Ala202Ala NOTCH3 polymorphism and earlier first-ever stroke or migraine.
|
25819272 |
2015 |
rs1044498
|
|
|
0.010 |
GeneticVariation |
BEFREE |
One mutation in GOLGB1 (Y1212C) and another mutation in ENPP1 (K173Q) were confirmed as having significant associations with a decreased risk for stroke.
|
23422753 |
2013 |
rs10455872
|
|
|
0.700 |
GeneticVariation |
GWASCAT |
Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants.
|
24262325 |
2014 |
rs1045642
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Therefore the present study was taken up to investigate the role of C3435T polymorphism (rs 1045642) of multiple drug resistance-1 (MDR-1) gene with aspirin resistance in stroke patients.
|
22177087 |
2012 |
rs1045642
|
|
|
0.030 |
GeneticVariation |
BEFREE |
In patients treated with clopidogrel, ABCB1 3435C→T genotype was significantly associated with the risk of cardiovascular death, myocardial infarction, or stroke (p=0·0064).
|
20801494 |
2010 |