|
rs1799983
|
|
|
0.050 |
GeneticVariation |
BEFREE |
The 894TT genotype of 894G>T (Glu298Asp, rs1799983), a polymorphic variant of eNOS, has been associated with several vascular diseases.
|
23512673 |
2013 |
|
rs1799983
|
|
|
0.050 |
GeneticVariation |
BEFREE |
Endothelial nitric oxide synthase (eNOS) G894T polymorphism has been previously associated with vascular diseases including stroke, but often with conflicting results.
|
22004707 |
2011 |
|
rs1799983
|
|
|
0.050 |
GeneticVariation |
BEFREE |
The eNOS gene polymorphism at position 894 (G>T, Glu298Asp) resulting in T allele has been studied in the context of vascular diseases, but its role in sepsis has not yet been explored.
|
18827745 |
2009 |
|
rs1799983
|
|
|
0.050 |
GeneticVariation |
BEFREE |
The Glu298Asp (G894T) polymorphic variant of eNOS has been associated with vascular disease, but functional data are lacking.
|
11298374 |
2001 |
|
rs397507444
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Mutations or polymorphisms in the gene of the enzyme methylenetetrahydrofolate reductase (MTHFR), as C677T, A1298C and G1793A, are associated with hyperhomocysteinemia and possibly with elevated risk for vascular diseases.
|
17966140 |
2007 |
|
rs397507444
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Two common polymorphisms (677C>T and 1298A>C) in the gene coding for MTHFR have been shown to reduce MTHFR enzyme activity and were associated with the susceptibility to different disorders, including vascular disease, neural tube defects and lymphoid malignancies.
|
15921520 |
2005 |
|
rs397507444
|
|
|
0.040 |
GeneticVariation |
BEFREE |
The prevalences of the C677T and A1298C genotypes did not differ significantly in 772 individuals with documented coronary artery disease (CAD), 137 individuals with deep-vein thrombosis (DVT), and 329 individuals without documented vascular disease.
|
11274015 |
2001 |
|
rs397507444
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Further studies are needed to establish whether the C677T and the A1298C mutations have an impact on vascular disease in the Ashkenazi Jewish population.
|
10494095 |
1999 |
|
rs2303790
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Similarly, rs2303790 was not associated with any vascular diseases or plaque.
|
29141072 |
2018 |
|
rs2303790
|
|
|
0.030 |
GeneticVariation |
BEFREE |
To detect cholesteryl ester transfer protein (CETP) levels, frequencies of CETP D442G and I 14A mutations and characteristics of abnormal lipids in patients with cardio-cerebro vascular diseases.
|
11940367 |
2002 |
|
rs2303790
|
|
|
0.030 |
GeneticVariation |
BEFREE |
We compared the genotype distribution of the D442G polymorphism and postprandial serum lipid levels between patients with and without VD in 414 hemodialysis patients.
|
10412772 |
1999 |
|
rs112735431
|
|
|
0.020 |
GeneticVariation |
BEFREE |
We were able to determine genetic predisposition to angiopathy by identifying the RNF213 c.14576G>A (rs112735431, p.R4859K) mutation.
|
31818681 |
2020 |
|
rs11591147
|
|
|
0.020 |
GeneticVariation |
BEFREE |
R46L polymorphism in the PCSK9 gene: Relationship to lipid levels, subclinical vascular disease, and erectile dysfunction.
|
29773421 |
2019 |
|
rs112735431
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Accumulating studies have reported that there is an association between the Ring finger protein 213 (RNF213) p.R4810K (rs112735431, c.14576G>A) single nucleotide polymorphism and the predisposition of moyamoya disease (MMD), intracranial major artery stenosis/occlusion (ICASO), quasi-moyamoya disease (quasi-MMD), and other vascular diseases.
|
29752070 |
2018 |
|
rs11591147
|
|
|
0.020 |
GeneticVariation |
BEFREE |
In this population 3.5% were carriers of the T allele at R46L, and these subjects had significantly (p<0.001) lower levels of LDL C (mean, -10%), no difference in LDL C lowering response to pravastatin, and a non-significant 19% unadjusted and 9% adjusted decreased risk of vascular disease at baseline, with no on trial effect.
|
18262190 |
2008 |
|
rs1805087
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Thus, the methionine synthase D919G mutation was found to be common in the Japanese general population, and it appears unlikely that this polymorphism has a major effect on homocysteine metabolism and/or the onset of vascular diseases.
|
9974410 |
1999 |
|
rs1805087
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The D919G mutation does not seem to be a risk factor for NTD or vascular disease.
|
9327029 |
1997 |
|
rs1042579
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The <i>TM</i> C1418T (rs1042579) polymorphism is associated with a high risk of cardiac-cerebral vascular diseases.
|
30008974 |
2018 |
|
rs1967309
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A nested case-control study examining the rs1967309 SNP in 1427 cases and 1532 matched controls selected from the 12 092-patient Assessment of Clinical Effects of Cholesteryl Ester Transfer Protein Inhibition with Evacetrapib in Patients at a High Risk for Vascular Outcomes (ACCELERATE) trial, a randomized, double-blind, placebo-controlled phase 3 trial conducted in patients with high-risk vascular disease randomized from October 2012 through December 2013.
|
29525816 |
2018 |
|
rs759985000
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The manganese-dependent superoxide dismutase (MnSOD) Ala16Val single nucleotide polymorphism (SNP) has shown to be associated to risk factors of vascular diseases.
|
30150066 |
2018 |
|
rs763000109
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The manganese-dependent superoxide dismutase (MnSOD) Ala16Val single nucleotide polymorphism (SNP) has shown to be associated to risk factors of vascular diseases.
|
30150066 |
2018 |
|
rs4880
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The ALA16VAL-MnSOD gene single nucleotide polymorphism (SNP) has shown to modulate risk factors of several metabolic and vascular diseases, such as blood glucose (GLU) and lipid levels.
|
28552711 |
2017 |
|
rs9939609
|
|
|
0.010 |
GeneticVariation |
BEFREE |
To investigate whether the FTO rs9939609 single nucleotide polymorphism (SNP), which is a risk factor for obesity and vascular diseases, is also associated with pregnancy complications including pre-eclampsia, gestational hypertension, small for gestational age pregnancy (SGA), and spontaneous preterm birth (sPTB).
|
27768255 |
2016 |
|
rs387906853
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A previously described missense mutation, p.E239K, in the SMAD3 gene was identified in a 60-year-old man who presented with diffuse vasculopathy.
|
25555948 |
2015 |
|
rs764821003
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A previously described missense mutation, p.E239K, in the SMAD3 gene was identified in a 60-year-old man who presented with diffuse vasculopathy.
|
25555948 |
2015 |