|
rs1003897973
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We failed to confirm earlier reports of increased cervical cancer susceptibility in women who harbor the p53 P72R allele.
|
12142377 |
2002 |
|
rs1007541
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Stratification according to FIGO staging revealed that the minor allele of rs1007541 was more frequent among advanced tumor stage patients, with 11-fold increased risk of CC [P < 0.0001; OR (95 % CI) = 11.32 (7.46-17.18)].
|
27844329 |
2017 |
|
rs1030389
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Analysis of the SNPs after stratification based on CC clinical stage and subtype revealed that rs1048512, rs6659346, rs217727, rs9931702, and rs9302648 were associated with CC risk in clinical stages I-II; rs2862833, rs2732044, rs1030389, and rs1045935 were associated with CC risk in clinical stages III-IV; and rs217727, rs9931702, and rs9302648 were associated with CC risk in squamous carcinomas.
|
27765929 |
2016 |
|
rs1041981
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A significant association of CxCa with various polymorphisms was observed: rs1800797 in the IL-6 gene (odds ratio [OR] = 0.88, 95% confidence intervals [CI]: 0.79-0.99); rs1041981 in the LTA gene (OR = 0.87, 95% CI: 0.78-0.98), and rs9344 in the CCND1 gene (OR = 1.14, 95% CI: 1.02-1.27), for those individuals carrying the rare allele.
|
19585495 |
2009 |
|
rs1042522
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Driven by findings that human papillomavirus (HPV)-induced degradation of p53 differs by a TP53 polymorphism at codon 72 (Pro72Arg), past studies of TP53 genetic variants and cervical cancer have focused on this nonsynonymous polymorphism, with mixed results.
|
19423538 |
2009 |
|
rs1042522
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The results indicated that the polymorphism in TP53 (rs1042522) might be associated with risk of cervical cancer development in HPV16 infected women.
|
23534750 |
2013 |
|
rs1042522
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The Arg variant of p53 Arg72Pro is associated with progression of SIL to cervical cancer only in the presence of HPV positivity.
|
23065429 |
2012 |
|
rs1042522
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Women carrying the p53 Arg72Pro or p53 Pro72Pro increased the risk of cervical carcinoma (ORs and 95% CIs being 3.74 (2.65-5.30), 2.23 (1.49-3.34)).
|
19576684 |
2010 |
|
rs1042522
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We failed to confirm earlier reports of increased cervical cancer susceptibility in women who harbor the p53 P72R allele.
|
12142377 |
2002 |
|
rs1042522
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The present hospital-based retrospective cohort study aimed to evaluate the influence of <i>TP53</i> Arg72Pro (rs1042522) polymorphism in the clinical outcome of 260 Caucasian patients diagnosed with cervical cancer and treated with concomitant radiotherapy and chemotherapy.
|
29731921 |
2018 |
|
rs1042522
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The aim of the present study was to analyze the association of p53 codon72 (arginine/proline) polymorphism (rs1042522) and Murine Double Minute 2 (MDM2) SNP309 T/G (rs2279744) with the advancement of cervical cancer by using polymerase chain reaction-restriction fragment length polymorphism method followed by direct sequencing.
|
23210739 |
2013 |
|
rs1042522
|
|
|
0.100 |
GeneticVariation |
BEFREE |
To better understand the role of this polymorphism in cervical cancer etiology, we investigated the association between p53 R72P and cervical cancer risk in Chinese women from southern Han.
|
20193851 |
2010 |
|
rs1042522
|
|
|
0.100 |
GeneticVariation |
BEFREE |
A hundred HIV-infected women were examined for HPV detection and its genotypes, as well as the frequencies of the SNPs Arg72Pro and SNP309 and their associations with CC risk factors.
|
25181402 |
2015 |
|
rs1042522
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Combined analysis revealed that the genotypes of rs4938723 CT/CC and TP53 Arg72Pro CG/CC had an increased cervical cancer risk (OR = 2.21, 95 % CI = 1.38-3.53).
|
26619844 |
2016 |
|
rs1042522
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The p53 R72P polymorphism does not influence cervical cancer development in a Portuguese population: a study in exfoliated cervical cells.
|
18205229 |
2008 |
|
rs1042522
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Genetic polymorphisms of p73 G4C14-to-A4T14 at exon 2 and p53 Arg72Pro and the risk of cervical cancer in Japanese.
|
15036661 |
2004 |
|
rs1042522
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The aim of this Human Genome Epidemiology (HuGE) review and meta-analysis was to derive a more precise estimation of the association between p53 codon 72 polymorphism (Arg72Pro, rs1042522 G>C) and cervical cancer risk among Asians.
|
23244080 |
2012 |
|
rs1042522
|
|
|
0.100 |
GeneticVariation |
BEFREE |
These results suggest that a heterozygous TP53 Arg72Pro genotype may contribute to cervical cancer susceptibility.
|
21665181 |
2011 |
|
rs10426502
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The stratified analysis showed that <i>TNFAIP8L1</i>-rs10426502, -rs1060555, and <i>FLT1</i>-rs9513111 were associated with a decreased risk of cervical cancer amongst people older than 43 years.
|
31289124 |
2019 |
|
rs1042725
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The minor allele "C" of rs1042725 in HMGA2 was associated with an increased risk of CC in the allele, dominant and log-additive models.
|
27677077 |
2016 |
|
rs1045935
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Analysis of the SNPs after stratification based on CC clinical stage and subtype revealed that rs1048512, rs6659346, rs217727, rs9931702, and rs9302648 were associated with CC risk in clinical stages I-II; rs2862833, rs2732044, rs1030389, and rs1045935 were associated with CC risk in clinical stages III-IV; and rs217727, rs9931702, and rs9302648 were associated with CC risk in squamous carcinomas.
|
27765929 |
2016 |
|
rs1047840
|
|
|
0.010 |
GeneticVariation |
BEFREE |
These findings indicate that the SNPs of EXO1 K589E may contribute to cervical cancer carcinogenesis in Chinese populations.
|
22146767 |
2012 |
|
rs1048512
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Analysis of the SNPs after stratification based on CC clinical stage and subtype revealed that rs1048512, rs6659346, rs217727, rs9931702, and rs9302648 were associated with CC risk in clinical stages I-II; rs2862833, rs2732044, rs1030389, and rs1045935 were associated with CC risk in clinical stages III-IV; and rs217727, rs9931702, and rs9302648 were associated with CC risk in squamous carcinomas.
|
27765929 |
2016 |
|
rs1048638
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In conclusion, the finding that the <i>CA9</i> </span>SNP rs1</span>048638 exerts its action through duplexes of the miR-34a and <i>CA9</i> 3'-UTRs and plays a vital role in cervical cancer in Taiwanese women may be applicable to translational medicine.
|
29100431 |
2017 |
|
rs104886003
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The PIK3CA E542K and E545K mutations promote glycolysis and proliferation via induction of the β-catenin/SIRT3 signaling pathway in cervical cancer.
|
30547809 |
2018 |