|
rs1130214
|
|
|
0.010 |
GeneticVariation |
BEFREE |
None of the effects reported in earlier studies were statistically significant, including the association between rs3803300 and BD without any psychotic symptoms, rs3803300 and mood-congruent psychosis, rs3803300 and the combined groups, as well as the association between the haplotypes formed by rs3730358 and rs1130214 and risk for BD.
|
31810747 |
2020 |
|
rs3730358
|
|
|
0.010 |
GeneticVariation |
BEFREE |
None of the effects reported in earlier studies were statistically significant, including the association between rs3803300 and BD without any psychotic symptoms, rs3803300 and mood-congruent psychosis, rs3803300 and the combined groups, as well as the association between the haplotypes formed by rs3730358 and rs1130214 and risk for BD.
|
31810747 |
2020 |
|
rs1137101
|
|
|
0.010 |
GeneticVariation |
BEFREE |
To determine whether genetic polymorphisms related to pharmacodynamics with metabolic adverse effects, namely leptin promoter (<i>LEP</i>) rs7799039, leptin receptor rs1137101, dopamine D2 rs4436578, serotonin 5-HT2A rs6313, and serotonin 5-HT2C rs518147 and rs12836771, are associated with hyperglycemia induced by risperidone or clozapine in adult Thai patients with psychosis.
|
31496784 |
2019 |
|
rs12836771
|
|
|
0.010 |
GeneticVariation |
BEFREE |
To determine whether genetic polymorphisms related to pharmacodynamics with metabolic adverse effects, namely leptin promoter (<i>LEP</i>) rs7799039, leptin receptor rs1137101, dopamine D2 rs4436578, serotonin 5-HT2A rs6313, and serotonin 5-HT2C rs518147 and rs12836771, are associated with hyperglycemia induced by risperidone or clozapine in adult Thai patients with psychosis.
|
31496784 |
2019 |
|
rs165940
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Further analysis using additional cohorts and endophenotypes revealed that rs165940 principally associates within the psychosis (p = 0.025, OR = 1.18, 95% CI: 1.07-1.30) and cognitive domains of major mental illnesses (g-score p = 0.044, β = -0.033).
|
31138891 |
2019 |
|
rs4436578
|
|
|
0.010 |
GeneticVariation |
BEFREE |
To determine whether genetic polymorphisms related to pharmacodynamics with metabolic adverse effects, namely leptin promoter (<i>LEP</i>) rs7799039, leptin receptor rs1137101, dopamine D2 rs4436578, serotonin 5-HT2A rs6313, and serotonin 5-HT2C rs518147 and rs12836771, are associated with hyperglycemia induced by risperidone or clozapine in adult Thai patients with psychosis.
|
31496784 |
2019 |
|
rs518147
|
|
|
0.010 |
GeneticVariation |
BEFREE |
To determine whether genetic polymorphisms related to pharmacodynamics with metabolic adverse effects, namely leptin promoter (<i>LEP</i>) rs7799039, leptin receptor rs1137101, dopamine D2 rs4436578, serotonin 5-HT2A rs6313, and serotonin 5-HT2C rs518147 and rs12836771, are associated with hyperglycemia induced by risperidone or clozapine in adult Thai patients with psychosis.
|
31496784 |
2019 |
|
rs61749465
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The evidence for association between rs61749465A>G and psychosis in both BPD and SCZ warrants further replication.
|
30859703 |
2019 |
|
rs7799039
|
|
|
0.010 |
GeneticVariation |
BEFREE |
To determine whether genetic polymorphisms related to pharmacodynamics with metabolic adverse effects, namely leptin promoter (<i>LEP</i>) rs7799039, leptin receptor rs1137101, dopamine D2 rs4436578, serotonin 5-HT2A rs6313, and serotonin 5-HT2C rs518147 and rs12836771, are associated with hyperglycemia induced by risperidone or clozapine in adult Thai patients with psychosis.
|
31496784 |
2019 |
|
rs2228145
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Asp358Ala was not associated with any of the other risk factors commonly linked with inflammation, depression or psychosis (all P > 0.20).
|
29197507 |
2018 |
|
rs3761554
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We observed no evidence of association with METH dependence and METH-dependent psychosis in the GRIA1 and GRIA2 polymorphisms, nor with single polymorphisms rs3761554 and rs989638 in GRIA3.
|
29338492 |
2018 |
|
rs502434
|
|
|
0.010 |
GeneticVariation |
BEFREE |
An association of GRIA3 rs502434 was identified with both METH dependence and METH-dependent psychosis, although this did not withstand correction for multiple testing.
|
29338492 |
2018 |
|
rs989638
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We observed no evidence of association with METH dependence and METH-dependent psychosis in the GRIA1 and GRIA2 polymorphisms, nor with single polymorphisms rs3761554 and rs989638 in GRIA3.
|
29338492 |
2018 |
|
rs10494561
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our analyses found that rs10494561, located in the intron region within NMNAT2, was associated with the severity of the prodromal symptoms of psychosis implicitly, mediated through the volume of the left hemisphere of the superior frontal region ( P=2.38×10-8).
|
28544218 |
2017 |
|
rs10503929
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In a 3-year prospective study cohort of 185 individuals (age: 13-35 years) at high risk and ultra-high risk (UHR) for psychosis, we assessed <i>DAO</i> (rs3918347, rs4623951), <i>DAOA</i> (rs778293, rs3916971, rs746187), and <i>NRG1</i> (rs10503929) SNPs and their mRNA expression.
|
29326614 |
2017 |
|
rs12807809
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Minor allele C of rs12807809 polymorphism in NRGN contributes to the severity of psychosis in patients with Schizophrenia in South Indian population.
|
28389239 |
2017 |
|
rs1800955
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Baseline clinical, psychosis-risk status, cognitive, neurological-soft-signs measures, and dopamine-related-gene polymorphisms (DRD1-rs4532, COMT-rs165599, and DRD4-rs1800955) were collected in 138 young non-psychotic outpatients.
|
28041918 |
2017 |
|
rs1801133
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Disorganization is associated with early schizophrenia onset and history of psychosis in family, low level of insight and compliance, high risk of committing delicts, distraction errors in WCST, lengthened P300 latency of evoked cognitive auditory potentials, low-functional alleles of genes MTHFR (rs1801133) and DNMT3b (rs2424913), high level of urbanicity and psychotraumatic events at early age.
|
28192769 |
2017 |
|
rs2007044
|
|
|
0.010 |
GeneticVariation |
BEFREE |
This included an association between the rs2007044 (risk allele G) within CACNA1C and poorer working memory performance (increased errors B (95% CI)=0.635-4.535, p=0.012), an effect driven mainly by the psychosis groups.
|
28607492 |
2017 |
|
rs2236418
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The genotype and allele frequencies of rs2236418 (GAD2) were associated with METH dependence and METH with psychosis, in which the G allele was related to increased risk.
|
27967329 |
2017 |
|
rs2424913
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Disorganization is associated with early schizophrenia onset and history of psychosis in family, low level of insight and compliance, high risk of committing delicts, distraction errors in WCST, lengthened P300 latency of evoked cognitive auditory potentials, low-functional alleles of genes MTHFR (rs1801133) and DNMT3b (rs2424913), high level of urbanicity and psychotraumatic events at early age.
|
28192769 |
2017 |
|
rs6465084
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Despite limited literature, studies demonstrated: single nucleotide polymorphisms (SNPs) associated with BD, including a GRM3 SNP associated with greater likelihood of psychosis (rs6465084), mRNA binding protein Fragile X Mental Retardation Protein associated with altered mGluR1/5 activity in BD populations, and lithium decreasing mGluR5 expression and mGluR-mediated intracellular calcium signaling.
|
28800512 |
2017 |
|
rs701428
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Moreover, occipital gray matter volumes were robustly associated with ultra high risk symptoms of psychosis in the presence of the G allele of rs701428.
|
28139055 |
2017 |
|
rs701492
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The presence of the rs769404-rs701492 (GAD1) C-C haplotype was associated with METH psychosis.
|
27967329 |
2017 |
|
rs769404
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The presence of the rs769404-rs701492 (GAD1) C-C haplotype was associated with METH psychosis.
|
27967329 |
2017 |