rs1447295
|
|
|
0.800 |
GeneticVariation |
BEFREE |
Overall, there was a positive association between carriers of the allele A of rs1447295 and prostate cancer risk [odds ratio (OR), 1.60; 95% confidence interval (95% CI), 1.01-2.52] but no significant association with carriers of alleles A of rs16901979 and allele G of rs6983267.
|
18768513 |
2008 |
rs1447295
|
|
|
0.800 |
GeneticVariation |
GWASDB |
Multiple newly identified loci associated with prostate cancer susceptibility.
|
18264097 |
2008 |
rs1447295
|
|
|
0.800 |
GeneticVariation |
GWASDB |
Multiple loci identified in a genome-wide association study of prostate cancer.
|
18264096 |
2008 |
rs1447295
|
|
|
0.800 |
GeneticVariation |
BEFREE |
The rs1447295 A allele was associated with susceptibility to PC (PC vs. non-PC: P = 0.041; OR, 1.28; 95%CI = 1.01-1.61), and was more significantly associated with disease in aggressive PC (aggressive PC vs. normal controls, P = 0.013; OR, 1.43; 95%CI = 1.08-1.90).
|
18726982 |
2008 |
rs1447295
|
|
|
0.800 |
GeneticVariation |
BEFREE |
We conclude that the A allele of rs1447295 is associated with a higher risk of prostate cancer regardless of tumor aggressiveness, suggesting that such a variant, or a variant in linkage disequilibrium with it, plays a role early in prostate carcinogenesis.
|
17372260 |
2007 |
rs1447295
|
|
|
0.800 |
GeneticVariation |
BEFREE |
These results further confirm the importance of these two polymorphic variants (rs1447295 and DG8S737) as risk factors for PC.
|
17409399 |
2007 |
rs1447295
|
|
|
0.800 |
GeneticVariation |
BEFREE |
We identified multiple SNPs in a 50-kb region (referred to as locus 1) that are in linkage disequilibrium with a previously reported risk-associated SNP at 8q24, rs1447295, but were more strongly associated with prostate cancer risk in our study population.
|
17925536 |
2007 |
rs1447295
|
|
A |
0.800 |
GeneticVariation |
GWASDB |
Genome-wide association study of prostate cancer identifies a second risk locus at 8q24.
|
17401363 |
2007 |
rs1447295
|
|
|
0.800 |
GeneticVariation |
BEFREE |
Overall, there was a significant positive association between the A allele of the SNP rs1447295 and prostate cancer risk [odds ratio, 1.4; 95% confidence interval (95% CI), 1.1-2.0] but no significant association with the microsatellite DG8S737.
|
17416775 |
2007 |
rs1447295
|
|
|
0.800 |
GeneticVariation |
BEFREE |
The rs1447295 marker was strongly associated with prostate cancer among Caucasians (P = 1.23 x 10(-13)).
|
17409400 |
2007 |
rs1447295
|
|
A |
0.800 |
GeneticVariation |
GWASDB |
Genome-wide association study identifies a second prostate cancer susceptibility variant at 8q24.
|
17401366 |
2007 |