Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2476601
rs2476601
PTPN22 ; AP4B1-AS1
0.850 GeneticVariation BEFREE The C1858T polymorphism of the PTNP22 gene reduces the expression of its encoded LYP, which increases the risk of GD and HT. 28133421

2017
dbSNP: rs2476601
rs2476601
PTPN22 ; AP4B1-AS1
0.850 GeneticVariation BEFREE (3) regarding the subtypes of AITDs, patients with Graves' disease (GD) had a significant higher degree of C1858T polymorphism (TT vs. CC, OR=2.35, 95%CI=1.36˜4.05; TC vs. CC, OR=1.46, 95%CI=1.12˜1.89; TT/TC vs. CC, OR=1.54, 95%CI=1.33˜1.80; TT vs. TC/CC, OR=2.16, 95%CI=1.25˜3.72), while no association was observed in patients with Hashimoto's thyroiditis (HT).No publication bias was observed. 22374238

2012
dbSNP: rs2476601
rs2476601
PTPN22 ; AP4B1-AS1
A 0.850 GeneticVariation GWASCAT Seven newly identified loci for autoimmune thyroid disease. 22922229

2012
dbSNP: rs2476601
rs2476601
PTPN22 ; AP4B1-AS1
0.850 GeneticVariation GWASDB Seven newly identified loci for autoimmune thyroid disease. 22922229

2012
dbSNP: rs2476601
rs2476601
PTPN22 ; AP4B1-AS1
0.850 GeneticVariation BEFREE To evaluate the prevalence of PTPN22 C1858T polymorphism in young type 1 diabetes patients with or without autoimmune thyroiditis. 20438787

2010
dbSNP: rs2476601
rs2476601
PTPN22 ; AP4B1-AS1
0.850 GeneticVariation BEFREE Stratifying patients affected with AITDs according to their phenotype (Graves' disease and Hashimoto's thyroiditis) and RA patients according to the presence of rheumatoid factor (RF) and antibodies against cyclic citrullinated peptides (ACPA) did not show any significant association with PTPN22 R620W allele (p>0.05). 19343596

2009
dbSNP: rs2476601
rs2476601
PTPN22 ; AP4B1-AS1
0.850 GeneticVariation BEFREE The minor allele of the R620W missense single-nucleotide polymorphism (SNP; rs2476601) in the PTPN22 (protein tyrosine phosphatase non-receptor 22) gene has been reported to be associated with multiple autoimmune diseases, including type 1 diabetes, systemic lupus erythematosus, rheumatoid arthritis, juvenile idiopathic arthritis, autoimmune thyroiditis and vitiligo. 16464986

2006
dbSNP: rs7537605
rs7537605
VAV3
0.710 GeneticVariation BEFREE A genome-wide direct comparison between HT and GD revealed an SNP at the VAV3 locus with genome-wide significant association signals (rs7537605: P(combined) = 3.90 × 10(-8); odds ratio(combined) = 1.77; 95% confidence interval = 1.44-2.17). 25429627

2015
dbSNP: rs7537605
rs7537605
VAV3
0.710 GeneticVariation GWASCAT A genome-wide direct comparison between HT and GD revealed an SNP at the VAV3 locus with genome-wide significant association signals (rs7537605: P(combined) = 3.90 × 10(-8); odds ratio(combined) = 1.77; 95% confidence interval = 1.44-2.17). 25429627

2015
dbSNP: rs12507813
rs12507813 		G 0.700 GeneticVariation GWASCAT Genome-wide association analysis suggests novel loci underlying thyroid antibodies in Hashimoto's thyroiditis. 30926877

2019
dbSNP: rs12551356
rs12551356 		G 0.700 GeneticVariation GWASCAT Genome-wide association analysis suggests novel loci underlying thyroid antibodies in Hashimoto's thyroiditis. 30926877

2019
dbSNP: rs2056252
rs2056252
TRIM60
G 0.700 GeneticVariation GWASCAT Genome-wide association analysis suggests novel loci underlying thyroid antibodies in Hashimoto's thyroiditis. 30926877

2019
dbSNP: rs6972286
rs6972286 		A 0.700 GeneticVariation GWASCAT Genome-wide association analysis suggests novel loci underlying thyroid antibodies in Hashimoto's thyroiditis. 30926877

2019
dbSNP: rs7085433
rs7085433
TIMM23
G 0.700 GeneticVariation GWASCAT Genome-wide association analysis suggests novel loci underlying thyroid antibodies in Hashimoto's thyroiditis. 30926877

2019
dbSNP: rs756763
rs756763
CA10
A 0.700 GeneticVariation GWASCAT Genome-wide association analysis suggests novel loci underlying thyroid antibodies in Hashimoto's thyroiditis. 30926877

2019
dbSNP: rs977706
rs977706 		A 0.700 GeneticVariation GWASCAT Genome-wide association analysis suggests novel loci underlying thyroid antibodies in Hashimoto's thyroiditis. 30926877

2019
dbSNP: rs2270450
rs2270450
SLC25A27 ; LOC101926934
T 0.700 GeneticVariation GWASCAT Identification of a Hashimoto thyroiditis susceptibility locus via a genome-wide comparison with Graves' disease. 25429627

2015
dbSNP: rs11571297
rs11571297 		G 0.700 GeneticVariation GWASCAT Seven newly identified loci for autoimmune thyroid disease. 22922229

2012
dbSNP: rs13093110
rs13093110
LPP
T 0.700 GeneticVariation GWASCAT Seven newly identified loci for autoimmune thyroid disease. 22922229

2012
dbSNP: rs1534422
rs1534422
MIR3681HG
G 0.700 GeneticVariation GWASCAT Seven newly identified loci for autoimmune thyroid disease. 22922229

2012
dbSNP: rs4409785
rs4409785 		C 0.700 GeneticVariation GWASCAT Seven newly identified loci for autoimmune thyroid disease. 22922229

2012
dbSNP: rs57348955
rs57348955 		G 0.700 GeneticVariation GWASCAT Seven newly identified loci for autoimmune thyroid disease. 22922229

2012
dbSNP: rs706779
rs706779
IL2RA
A 0.700 GeneticVariation GWASCAT Seven newly identified loci for autoimmune thyroid disease. 22922229

2012
dbSNP: rs72928038
rs72928038
BACH2
A 0.700 GeneticVariation GWASCAT Seven newly identified loci for autoimmune thyroid disease. 22922229

2012
dbSNP: rs1085308054
rs1085308054
PTEN
C 0.700 CausalMutation CLINVAR