|
rs3218536
|
|
|
0.060 |
GeneticVariation |
BEFREE |
Overall, a significant association was found between the Arg188His polymorphism and ovarian cancer risk when all studies were pooled into the meta-analysis (Arg/Arg vs His/His: OR = 1.85, 95%CI = 1.15-3.00; Arg/Arg vs Arg/His: OR = 1.17, 95%CI = 1.03-1.32; dominant model: OR = 0.84, 95%CI = 0.74-0.95; recessive model: OR = 1.69, 95%CI = 1.05-2.70).
|
26400309 |
2015 |
|
rs3218536
|
|
|
0.060 |
GeneticVariation |
BEFREE |
In conclusion, this meta-analysis indicates that XRCC2 rs3218536 and ERCC2 rs13181 polymorphisms may not be associated with the risk of OC.
|
27863412 |
2016 |
|
rs3218536
|
|
|
0.060 |
GeneticVariation |
BEFREE |
The current meta-analysis indicated that the Arg188His polymorphism in the XRCC2 gene might be a risk factor for ovarian cancer.
|
24414483 |
2014 |
|
rs3218536
|
|
|
0.060 |
GeneticVariation |
BEFREE |
The aim of the present study was to evaluate the role of SNPs in three genes, XRCC2 (R188H), ERCC2 (K751Q) and CDKN1B (V109G) which are with moderate risk for ovarian cancer susceptibility in Egyptian women.
|
23277402 |
2013 |
|
rs3218536
|
|
|
0.060 |
GeneticVariation |
BEFREE |
The obtained results indicate that XRCC2 Arg188His and XRCC3 Thr241Met polymorphisms may be positively associated with the incidence of ovarian carcinoma in the population of Polish women.
|
26801223 |
2016 |
|
rs3218536
|
|
|
0.060 |
GeneticVariation |
BEFREE |
Interestingly, XRCC2 G>A (rs3218536) polymorphism might reduce the risk of ovarian cancer.
|
24599673 |
2014 |
|
rs587780128
|
|
|
0.010 |
GeneticVariation |
BEFREE |
These mutations and variants were detected in families with both breast and ovarian cancers, except for the RAD51B c.475C > T/p.Arg159Cys variant that occurred in a family with 3 breast cancer cases.
|
24139550 |
2013 |
|
rs25487
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Impact of RAD51 G135C and XRCC1 Arg399Gln polymorphisms on ovarian carcinoma risk in Serbian women.
|
26406958 |
2015 |
|
rs25487
|
|
|
0.030 |
GeneticVariation |
BEFREE |
This study indicated that XRCC1 Arg194Trp, Arg280His, and Arg399Gln did not affect OS after platinum-based chemotherapy in OC patients.
|
30407287 |
2018 |
|
rs25487
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Our study found a significant association between XRCC1 Arg399Gln and XRCC1 Arg194Trp polymorphism and the clinical outcome of ovarian cancer.
|
22983827 |
2013 |
|
rs1799782
|
|
|
0.020 |
GeneticVariation |
BEFREE |
In conclusion, hOGG1 Ser326Cys and XRCC1 Arg194Trp polymorphisms may be regarded as risk factors of ovarian cancer.
|
26124010 |
2015 |
|
rs1799782
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Our study found a significant association between XRCC1 Arg399Gln and XRCC1 Arg194Trp polymorphism and the clinical outcome of ovarian cancer.
|
22983827 |
2013 |
|
rs1222213359
|
|
|
0.010 |
GeneticVariation |
BEFREE |
None of the five genetic models suggested a significant association between -1154G/A and ovarian cancer risk in the entire study population, or between +936C/T and risk in Asian or Chinese participants.
|
29069849 |
2017 |
|
rs2146323
|
|
|
0.010 |
GeneticVariation |
BEFREE |
VEGF tagSNPs rs3025033 and rs2146323 were not associated with ovarian cancer survival in the Australian sample.
|
20832104 |
2010 |
|
rs3025033
|
|
|
0.010 |
GeneticVariation |
BEFREE |
VEGF tagSNPs rs3025033 and rs2146323 were not associated with ovarian cancer survival in the Australian sample.
|
20832104 |
2010 |
|
rs2228570
|
|
|
0.050 |
GeneticVariation |
BEFREE |
The VDR polymorphism FokI (rs2228570) seems to increase the risk of ovarian cancer.
|
29113037 |
2017 |
|
rs2228570
|
|
|
0.050 |
GeneticVariation |
BEFREE |
This pooled analysis provides further evidence that the VDR rs2228570 polymorphism might influence ovarian cancer susceptibility.
|
20473893 |
2011 |
|
rs2228570
|
|
|
0.050 |
GeneticVariation |
BEFREE |
The homozygote model with the rs2228570 (FokI) polymorphism model appeared to detect the risk of OC in all cases, whereas the heterozygote model with the rs1544410 (BsmI) polymorphism seemed to detect the risk of OC in Caucasian patients.
|
30059751 |
2018 |
|
rs2228570
|
|
|
0.050 |
GeneticVariation |
BEFREE |
More studies are warranted to assess the association between the VDR rs2228570 polymorphism and ovarian cancer in Asians and Africans.
|
24136742 |
2014 |
|
rs2228570
|
|
|
0.050 |
GeneticVariation |
BEFREE |
The rs2228570 polymorphism increased the risk of ovarian cancer in Caucasian populations in a dominant genetic model.
|
29239065 |
2018 |
|
rs1544410
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Moreover, for detecting clinical risk of OC, heterozygote models with the rs1544410 (BsmI) polymorphism is likely the best genetic model for detecting the risk of OC in Caucasian patients.
|
30059751 |
2018 |
|
rs3737787
|
|
|
0.010 |
GeneticVariation |
BEFREE |
This study was supposed to investigate the correlation between the functional single nucleotide polymorphisms (SNPs) (rs2516839 and rs3737787) in USF1 gene and the efficacy and safety of paclitaxel-based chemotherapy and prognosis in the treatment of ovarian cancer (OC).
|
29322800 |
2019 |
|
rs2516839
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Taken together, our results suggest that the rs2516839 polymorphism in USF1 gene may associate with the efficacy and safety of paclitaxel-based chemotherapy and prognosis in the treatment of OC.
|
29322800 |
2019 |
|
rs4648551
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We genotyped the p63 (rs873330 [Genbank, refSNP ID] T > C [T: original base, C: mutant base]) and p73 (rs4648551 G > A and rs6695978 G > A) SNPs in ovarian cancers and healthy controls and analyzed the distributions of genotype frequencies to evaluate the association of the genotypes with the risk of ovarian cancer and the clinicopathological characteristics.
|
23095717 |
2012 |
|
rs6695978
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The p73 rs6695978 G > A polymorphism will serve as a modifier of ovarian cancer susceptibility and prognosis.
|
23095717 |
2012 |