|
rs1805087
|
|
|
0.050 |
GeneticVariation |
BEFREE |
We also examined the relationship of a newly identified polymorphism (asp919gly) of the methionine synthase gene (MS) with the risk of colorectal adenomas in the same population.
|
9886567 |
1998 |
|
rs1217691063
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The methylenetetrahydrofolate reductase 677C-->T polymorphism and distal colorectal adenoma risk.
|
10919734 |
2000 |
|
rs1801166
|
|
|
0.050 |
GeneticVariation |
BEFREE |
E1317Q is significantly associated with multiple colorectal adenomas (OR = 11.
|
11001924 |
2000 |
|
rs34612342
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Here, we report the identification of seven further unrelated patients with >100 colorectal adenomas (six with colorectal cancer) and biallelic germline mutations in MYH: four were homozygous for truncating mutations, two were homozygous for Y165C and one was a Y165C/G382D compound heterozygote.
|
12393807 |
2002 |
|
rs770649674
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Here, we report the identification of seven further unrelated patients with >100 colorectal adenomas (six with colorectal cancer) and biallelic germline mutations in MYH: four were homozygous for truncating mutations, two were homozygous for Y165C and one was a Y165C/G382D compound heterozygote.
|
12393807 |
2002 |
|
rs1801166
|
|
|
0.050 |
GeneticVariation |
BEFREE |
In conclusion, our results confirm that only a very small fraction of colorectal adenomas</span> may be associated with the presence of E1317Q.
|
12537656 |
2002 |
|
rs1217691063
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Relation of plasma folate and methylenetetrahydrofolate reductase C677T polymorphism to colorectal adenomas.
|
12690011 |
2003 |
|
rs397507444
|
|
|
0.040 |
GeneticVariation |
BEFREE |
We examined folate and alcohol intake and genetic polymorphisms in methylenetetrahydrofolate reductase [MTHFR 667-->T (ala-->val) and MTHFR 1298A-->C (gln-->ala)] (associated with reduced MTHFR activity) and in alcohol dehydrogenase 3 [ADH3 (2-2) associated with decreased alcohol catabolism] in relation to risk of colorectal adenoma in the Health Professionals Follow-Up Study.
|
14578131 |
2003 |
|
rs1042028
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A genetic polymorphism leads to an Arg213His substitution, thereby decreasing enzyme activity and stability and might thus modify the association between smoking and colorectal adenomas.
|
14618622 |
2004 |
|
rs370302501
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A genetic polymorphism leads to an Arg213His substitution, thereby decreasing enzyme activity and stability and might thus modify the association between smoking and colorectal adenomas.
|
14618622 |
2004 |
|
rs9282861
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A genetic polymorphism leads to an Arg213His substitution, thereby decreasing enzyme activity and stability and might thus modify the association between smoking and colorectal adenomas.
|
14618622 |
2004 |
|
rs1805087
|
|
|
0.050 |
GeneticVariation |
BEFREE |
Methionine synthase D919G polymorphism, folate metabolism, and colorectal adenoma risk.
|
14744749 |
2004 |
|
rs1801166
|
|
|
0.050 |
GeneticVariation |
BEFREE |
The APC I1307K and E1317Q variants predispose to colorectal adenomas and carcinomas in Caucasians, but data are lacking in Asians.
|
15266213 |
2005 |
|
rs1463038513
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The APC I1307K and E1317Q variants predispose to colorectal adenomas and carcinomas in Caucasians, but data are lacking in Asians.
|
15266213 |
2005 |
|
rs1801155
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The APC I1307K and E1317Q variants predispose to colorectal adenomas and carcinomas in Caucasians, but data are lacking in Asians.
|
15266213 |
2005 |
|
rs1217691063
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Folate intake, MTHFR C677T polymorphism, alcohol consumption, and risk for sporadic colorectal adenoma (United States).
|
15286469 |
2004 |
|
rs1801282
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Smoking was a very strong risk factor (OR 2.34, 95%CI 1.37-4.02) for colorectal adenoma</span> among those with the wild-type (Pro12Ala) genotype, but not those with the Ala12 variant (OR 0.86, 95%CI 0.35-2.09).
|
15564289 |
2005 |
|
rs1805192
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Smoking was a very strong risk factor (OR 2.34, 95%CI 1.37-4.02) for colorectal adenoma</span> among those with the wild-type (Pro12Ala) genotype, but not those with the Ala12 variant (OR 0.86, 95%CI 0.35-2.09).
|
15564289 |
2005 |
|
rs861539
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Using a large sigmoidoscopy-based case-control study (753 cases and 799 controls) in Los Angeles County, we investigated possible associations between single-nucleotide polymorphisms in the XRCC1 (codons 194 Arg/Trp and codon 399 Arg/Gln) and XRCC3 (codon 241 Thr/Met) genes and colorectal adenoma risk and their possible role as modifiers of the effect of monounsaturated fatty acid, the ratio of omega-6/omega-3 polyunsaturated fatty acids, and antioxidant intake.
|
15767338 |
2005 |
|
rs1799782
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Using a large sigmoidoscopy-based case-control study (753 cases and 799 controls) in Los Angeles County, we investigated possible associations between single-nucleotide polymorphisms in the XRCC1 (codons 194 Arg/Trp and codon 399 Arg/Gln) and XRCC3 (codon 241 Thr/Met) genes and colorectal adenoma risk and their possible role as modifiers of the effect of monounsaturated fatty acid, the ratio of omega-6/omega-3 polyunsaturated fatty acids, and antioxidant intake.
|
15767338 |
2005 |
|
rs25487
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Using a large sigmoidoscopy-based case-control study (753 cases and 799 controls) in Los Angeles County, we investigated possible associations between single-nucleotide polymorphisms in the XRCC1 (codons 194 Arg/Trp and codon 399 Arg/Gln) and XRCC3 (codon 241 Thr/Met) genes and colorectal adenoma risk and their possible role as modifiers of the effect of monounsaturated fatty acid, the ratio of omega-6/omega-3 polyunsaturated fatty acids, and antioxidant intake.
|
15767338 |
2005 |
|
rs1217691063
|
|
|
0.100 |
GeneticVariation |
BEFREE |
No association was observed between MTHFR C677T genotype and colorectal adenomas.
|
15941973 |
2005 |
|
rs1052133
|
|
|
0.010 |
GeneticVariation |
BEFREE |
GPX Pro198Leu and OGG1 Ser326Cys polymorphisms and risk of development of colorectal adenomas and colorectal cancer.
|
15946795 |
2005 |
|
rs1245554802
|
|
|
0.010 |
GeneticVariation |
BEFREE |
No associations were found between the polymorphism GPX Pro198Leu and risk of colorectal adenomas or carcinomas.
|
15946795 |
2005 |
|
rs771306418
|
|
|
0.010 |
GeneticVariation |
BEFREE |
No associations were found between the polymorphism GPX Pro198Leu and risk of colorectal adenomas or carcinomas.
|
15946795 |
2005 |