|
rs1805087
|
|
|
0.050 |
GeneticVariation |
BEFREE |
We also examined the relationship of a newly identified polymorphism (asp919gly) of the methionine synthase gene (MS) with the risk of colorectal adenomas in the same population.
|
9886567 |
1998 |
|
rs1217691063
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The methylenetetrahydrofolate reductase 677C-->T polymorphism and distal colorectal adenoma risk.
|
10919734 |
2000 |
|
rs1801166
|
|
|
0.050 |
GeneticVariation |
BEFREE |
E1317Q is significantly associated with multiple colorectal adenomas (OR = 11.
|
11001924 |
2000 |
|
rs1801166
|
|
|
0.050 |
GeneticVariation |
BEFREE |
In conclusion, our results confirm that only a very small fraction of colorectal adenomas</span> may be associated with the presence of E1317Q.
|
12537656 |
2002 |
|
rs34612342
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Here, we report the identification of seven further unrelated patients with >100 colorectal adenomas (six with colorectal cancer) and biallelic germline mutations in MYH: four were homozygous for truncating mutations, two were homozygous for Y165C and one was a Y165C/G382D compound heterozygote.
|
12393807 |
2002 |
|
rs770649674
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Here, we report the identification of seven further unrelated patients with >100 colorectal adenomas (six with colorectal cancer) and biallelic germline mutations in MYH: four were homozygous for truncating mutations, two were homozygous for Y165C and one was a Y165C/G382D compound heterozygote.
|
12393807 |
2002 |
|
rs1217691063
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Relation of plasma folate and methylenetetrahydrofolate reductase C677T polymorphism to colorectal adenomas.
|
12690011 |
2003 |
|
rs397507444
|
|
|
0.040 |
GeneticVariation |
BEFREE |
We examined folate and alcohol intake and genetic polymorphisms in methylenetetrahydrofolate reductase [MTHFR 667-->T (ala-->val) and MTHFR 1298A-->C (gln-->ala)] (associated with reduced MTHFR activity) and in alcohol dehydrogenase 3 [ADH3 (2-2) associated with decreased alcohol catabolism] in relation to risk of colorectal adenoma in the Health Professionals Follow-Up Study.
|
14578131 |
2003 |
|
rs1217691063
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Folate intake, MTHFR C677T polymorphism, alcohol consumption, and risk for sporadic colorectal adenoma (United States).
|
15286469 |
2004 |
|
rs1805087
|
|
|
0.050 |
GeneticVariation |
BEFREE |
Methionine synthase D919G polymorphism, folate metabolism, and colorectal adenoma risk.
|
14744749 |
2004 |
|
rs1042028
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A genetic polymorphism leads to an Arg213His substitution, thereby decreasing enzyme activity and stability and might thus modify the association between smoking and colorectal adenomas.
|
14618622 |
2004 |
|
rs370302501
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A genetic polymorphism leads to an Arg213His substitution, thereby decreasing enzyme activity and stability and might thus modify the association between smoking and colorectal adenomas.
|
14618622 |
2004 |
|
rs9282861
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A genetic polymorphism leads to an Arg213His substitution, thereby decreasing enzyme activity and stability and might thus modify the association between smoking and colorectal adenomas.
|
14618622 |
2004 |
|
rs1217691063
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Neither MTHFR C677T nor ALDH2 showed a measurable association with colorectal adenoma.
|
16108833 |
2005 |
|
rs1217691063
|
|
|
0.100 |
GeneticVariation |
BEFREE |
No association was observed between MTHFR C677T genotype and colorectal adenomas.
|
15941973 |
2005 |
|
rs1217691063
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Almost all of seven studies of colorectal adenoma have found no association between C677T polymorphism and adenoma, but the 677TT genotype seems to be related to increased risk when folate status is poor.
|
16128738 |
2005 |
|
rs1801166
|
|
|
0.050 |
GeneticVariation |
BEFREE |
The APC I1307K and E1317Q variants predispose to colorectal adenomas and carcinomas in Caucasians, but data are lacking in Asians.
|
15266213 |
2005 |
|
rs1463038513
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The APC I1307K and E1317Q variants predispose to colorectal adenomas and carcinomas in Caucasians, but data are lacking in Asians.
|
15266213 |
2005 |
|
rs1463038513
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Together with former evidence of I1307K being a risk factor for colorectal cancer, these data suggest that colonoscopic surveillance for colorectal adenomas and cancer may be warranted in I1307K carriers, even in the absence of other identifiable risk factors.
|
16228836 |
2005 |
|
rs1695
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The GSTM1 and GSTT1 deletion polymorphisms, and the single nucleotide polymorphisms in GSTP1 (A313G) and in GSTA1 (C-69T) were assessed among 746 cases who developed colorectal adenomas and 698 endoscopy-based controls without any type of colorectal polyps.
|
16365014 |
2005 |
|
rs1801155
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Together with former evidence of I1307K being a risk factor for colorectal cancer, these data suggest that colonoscopic surveillance for colorectal adenomas and cancer may be warranted in I1307K carriers, even in the absence of other identifiable risk factors.
|
16228836 |
2005 |
|
rs1801155
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The APC I1307K and E1317Q variants predispose to colorectal adenomas and carcinomas in Caucasians, but data are lacking in Asians.
|
15266213 |
2005 |
|
rs861539
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Using a large sigmoidoscopy-based case-control study (753 cases and 799 controls) in Los Angeles County, we investigated possible associations between single-nucleotide polymorphisms in the XRCC1 (codons 194 Arg/Trp and codon 399 Arg/Gln) and XRCC3 (codon 241 Thr/Met) genes and colorectal adenoma risk and their possible role as modifiers of the effect of monounsaturated fatty acid, the ratio of omega-6/omega-3 polyunsaturated fatty acids, and antioxidant intake.
|
15767338 |
2005 |
|
rs1052133
|
|
|
0.010 |
GeneticVariation |
BEFREE |
GPX Pro198Leu and OGG1 Ser326Cys polymorphisms and risk of development of colorectal adenomas and colorectal cancer.
|
15946795 |
2005 |
|
rs1198119472
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The GSTM1 and GSTT1 deletion polymorphisms, and the single nucleotide polymorphisms in GSTP1 (A313G) and in GSTA1 (C-69T) were assessed among 746 cases who developed colorectal adenomas and 698 endoscopy-based controls without any type of colorectal polyps.
|
16365014 |
2005 |