|
rs146795390
|
|
|
0.030 |
GeneticVariation |
BEFREE |
V843I, a lung cancer predisposing EGFR mutation, is responsible for resistance to EGFR tyrosine kinase inhibitors.
|
25057940 |
2014 |
|
rs833061
|
|
|
0.030 |
GeneticVariation |
BEFREE |
rs833061 and rs699947 on promoter gene of vascular endothelial growth factor (VEGF) and associated lung cancer susceptibility and survival: a meta-analysis.
|
25468805 |
2014 |
|
rs12901682
|
|
|
0.010 |
GeneticVariation |
BEFREE |
rs12901682 is associated with lung cancer risks (OR = 1.45, 95 % CI, 1.04-2.02; P = 0.029).
|
25744645 |
2015 |
|
rs121913465
|
|
|
0.010 |
GeneticVariation |
BEFREE |
S768I Mutation in EGFR in Patients with Lung Cancer.
|
27211795 |
2016 |
|
rs397517108
|
|
|
0.010 |
GeneticVariation |
BEFREE |
S768I Mutation in EGFR in Patients with Lung Cancer.
|
27211795 |
2016 |
|
rs121434569
|
|
|
0.100 |
GeneticVariation |
BEFREE |
T790M mutant copy number quantified via ddPCR predicts outcome after osimertinib treatment in lung cancer.
|
29963252 |
2018 |
|
rs121434569
|
|
|
0.100 |
GeneticVariation |
BEFREE |
A 79-year-old woman had disease progression during third-line treatment with osimertinib for an EGFR L858R/T790M-mutant lung cancer.
|
31254668 |
2019 |
|
rs3743078
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A case-control study of 529 cases and 567 controls was performed to study the association of three SNPs (rs3743076, rs3743078, and rs3743073) in CHRNA3 with lung cancer risk in Chinese Han population using logistic regression models.
|
20234319 |
2010 |
|
rs1130409
|
|
|
0.100 |
GeneticVariation |
BEFREE |
A common APE1 polymorphism, a T-->G transversion (Asp 148 Glu), was previously shown to be associated with risk of lung cancer, an association that was modified by cigarette smoking.
|
16425270 |
2006 |
|
rs1051740
|
|
|
0.080 |
GeneticVariation |
BEFREE |
A comprehensive systematic review and meta-analysis was performed of available studies on these two polymorphisms and cancer risk published up to November 2010, consisting of 84 studies (31144 cases and 42439 controls) for Tyr113His and 77 studies (28496 cases and 38506 controls) for His139Arg primarily focused on lung cancer, upper aerodigestive tract (UADT) cancers (including oral, pharynx, larynx and esophagus cancers), colorectal cancer or adenoma, bladder cancer and breast cancer.
|
21445251 |
2011 |
|
rs2234922
|
|
|
0.050 |
GeneticVariation |
BEFREE |
A comprehensive systematic review and meta-analysis was performed of available studies on these two polymorphisms and cancer risk published up to November 2010, consisting of 84 studies (31144 cases and 42439 controls) for Tyr113His and 77 studies (28496 cases and 38506 controls) for His139Arg primarily focused on lung cancer, upper aerodigestive tract (UADT) cancers (including oral, pharynx, larynx and esophagus cancers), colorectal cancer or adenoma, bladder cancer and breast cancer.
|
21445251 |
2011 |
|
rs146795390
|
|
|
0.030 |
GeneticVariation |
BEFREE |
A dramatic lung cancer course in a patient with a rare EGFR germline mutation exon 21 V843I: Is EGFR TKI resistance predictable?
|
23380224 |
2013 |
|
rs11637635
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A four-SNP haplotype spanning CHRNA5 (rs11637635 C, rs17408276 T, rs16969968 G) and CHRNA3 (rs578776 G) was associated with increased lung cancer risk (P = 0.002).
|
20587604 |
2010 |
|
rs17408276
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A four-SNP haplotype spanning CHRNA5 (rs11637635 C, rs17408276 T, rs16969968 G) and CHRNA3 (rs578776 G) was associated with increased lung cancer risk (P = 0.002).
|
20587604 |
2010 |
|
rs16969968
|
|
|
0.100 |
GeneticVariation |
BEFREE |
A four-SNP haplotype spanning CHRNA5 (rs11637635 C, rs17408276 T, rs16969968 G) and CHRNA3 (rs578776 G) was associated with increased lung cancer risk (P = 0.002).
|
20587604 |
2010 |
|
rs578776
|
|
|
0.040 |
GeneticVariation |
BEFREE |
A four-SNP haplotype spanning CHRNA5 (rs11637635 C, rs17408276 T, rs16969968 G) and CHRNA3 (rs578776 G) was associated with increased lung cancer risk (P = 0.002).
|
20587604 |
2010 |
|
rs9282861
|
|
|
0.050 |
GeneticVariation |
BEFREE |
A functional polymorphism in the SULT1A1 gene (G638A) is associated with risk of lung cancer in relation to tobacco smoking.
|
14688021 |
2004 |
|
rs1042028
|
|
|
0.040 |
GeneticVariation |
BEFREE |
A functional polymorphism in the SULT1A1 gene (G638A) is associated with risk of lung cancer in relation to tobacco smoking.
|
14688021 |
2004 |
|
rs967591
|
|
|
0.060 |
GeneticVariation |
BEFREE |
A functional variant at 19q13.3, rs967591G>A, is associated with shorter survival of early-stage lung cancer.
|
23775331 |
2013 |
|
rs577876
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A further comprehensive validation of 114 informative single nucleotide polymorphism (SNP) variants of PARK2, in 2,484 cases and controls with well-defined lung cancer and COPD phenotypes, found rs577876, rs6455728 and rs9346917 (p<0.01) to be significantly associated with lung cancer development in people with COPD.
|
27329585 |
2016 |
|
rs6455728
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A further comprehensive validation of 114 informative single nucleotide polymorphism (SNP) variants of PARK2, in 2,484 cases and controls with well-defined lung cancer and COPD phenotypes, found rs577876, rs6455728 and rs9346917 (p<0.01) to be significantly associated with lung cancer development in people with COPD.
|
27329585 |
2016 |
|
rs9346917
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A further comprehensive validation of 114 informative single nucleotide polymorphism (SNP) variants of PARK2, in 2,484 cases and controls with well-defined lung cancer and COPD phenotypes, found rs577876, rs6455728 and rs9346917 (p<0.01) to be significantly associated with lung cancer development in people with COPD.
|
27329585 |
2016 |
|
rs1799793
|
|
|
0.100 |
GeneticVariation |
BEFREE |
A haplotype encompassing the variant allele of DNA repair gene polymorphism ERCC2/XPD Lys751Gln but not the variant allele of Asp312Asn is associated with risk of lung cancer in a northeastern Chinese population.
|
17498557 |
2007 |
|
rs8034191
|
|
|
0.100 |
GeneticVariation |
BEFREE |
A meta-analysis provided increased support that variation at 15q25.1 (rs8034191; P = 3.24 x 10(-26)), 5p15.33 (rs4975616; P = 2.99 x 10(-9)), and 6p21.33 (rs3117582; P = 4.46 x 10(-10)) influences lung cancer risk.
|
19654303 |
2009 |
|
rs4975616
|
|
|
0.020 |
GeneticVariation |
BEFREE |
A meta-analysis provided increased support that variation at 15q25.1 (rs8034191; P = 3.24 x 10(-26)), 5p15.33 (rs4975616; P = 2.99 x 10(-9)), and 6p21.33 (rs3117582; P = 4.46 x 10(-10)) influences lung cancer risk.
|
19654303 |
2009 |