|
rs9939609
|
|
|
0.060 |
GeneticVariation |
BEFREE |
Distribution of FTO single nutleotide polymorphisms (SNPs) rs1421085T>C, rs9939609T>A, rs8057044G>A and copy number variation (CNV) was evaluated in association with childhood obesity or overweight status in children with Mayan ethnicity.
|
30537186 |
2019 |
|
rs9939609
|
|
|
0.060 |
GeneticVariation |
BEFREE |
This meta-analysis shows that the FTO rs9939609 polymorphism in the gene is a risk factor for obesity in children and adolescents with the presence of the A allele, both homozygous genotype AA situation, as heterozygous AT.
|
30104138 |
2019 |
|
rs9939609
|
|
|
0.060 |
GeneticVariation |
BEFREE |
We found no association of FTO rs9939609 with obesity in children and adolescents (p = 0.67).
|
29238857 |
2019 |
|
rs9939609
|
|
|
0.060 |
GeneticVariation |
BEFREE |
We showed that MC4R rs17782313 and FTO rs9939609 were positively associated with zBMI, with weak and very weak effects, respectively, suggesting a very scarce contribution to childhood obesity.
|
29679223 |
2018 |
|
rs9939609
|
|
|
0.060 |
GeneticVariation |
BEFREE |
The fat mass and obesity-associated gene (FTO) variant rs9939609 has been associated with increased risk of developing obesity in children and adults.
|
26222659 |
2015 |
|
rs9939609
|
|
|
0.060 |
GeneticVariation |
BEFREE |
The rs9939609 polymorphism of the fat mass and obesity-associated (FTO) gene has been widely associated with childhood obesity in several European cohorts.
|
21798115 |
2012 |
|
rs17782313
|
|
|
0.040 |
GeneticVariation |
BEFREE |
We showed that MC4R rs17782313 and FTO rs9939609 were positively associated with zBMI, with weak and very weak effects, respectively, suggesting a very scarce contribution to childhood obesity.
|
29679223 |
2018 |
|
rs17782313
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Our results strongly confirmed that rs17782313 was associated with increased risk of childhood obesity.
|
27926527 |
2017 |
|
rs17782313
|
|
|
0.040 |
GeneticVariation |
BEFREE |
MC4R polymorphism rs17782313 may contribute to childhood obesity, affecting enjoyment of food, satiety responsiveness, and possibly eating in the absence of hunger.
|
24139164 |
2014 |
|
rs17782313
|
|
|
0.040 |
GeneticVariation |
BEFREE |
To screen for mutations in the coding region of the melanocortin-4 receptor (MC4R) gene and to assess the association between the rs17782313 variant near MC4R with childhood obesity and eating behavior.
|
20406574 |
2010 |
|
rs1801282
|
|
|
0.030 |
GeneticVariation |
BEFREE |
LEPR rs1137101 and PPARG-2 rs1801282 had weak and medium negative effects on zBMI, respectively, and may slightly protect against childhood obesity.
|
29679223 |
2018 |
|
rs1801282
|
|
|
0.030 |
GeneticVariation |
BEFREE |
We observed that the calculated newborn's risk percentage for child obesity was greater for the variant allele of the TGF-β1 869 T > C polymorphism and also for the wild-type C allele of the PPARγ2 34 C > G gene polymorphism.
|
27442659 |
2016 |
|
rs1801282
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Peroxisome proliferator-activated receptor-gamma (PPARgamma) Pro12Ala polymorphism and risk for pediatric obesity.
|
19634985 |
2009 |
|
rs1137101
|
|
|
0.020 |
GeneticVariation |
BEFREE |
LEPR rs1137101 and PPARG-2 rs1801282 had weak and medium negative effects on zBMI, respectively, and may slightly protect against childhood obesity.
|
29679223 |
2018 |
|
rs1137101
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The GG genotype of leptin receptors rs1137101 and higher serum leptin levels can be used as risk factors for childhood obesity.
|
29412799 |
2018 |
|
rs6232
|
|
|
0.020 |
GeneticVariation |
BEFREE |
In addition to confirming rs6232 and rs6234 in <i>PCSK1</i> as polygenic risk variants for childhood obesity, we describe an association of rs725522 with insulin metabolism.
|
28271036 |
2017 |
|
rs1805192
|
|
|
0.020 |
GeneticVariation |
BEFREE |
We observed that the calculated newborn's risk percentage for child obesity was greater for the variant allele of the TGF-β1 869 T > C polymorphism and also for the wild-type C allele of the PPARγ2 34 C > G gene polymorphism.
|
27442659 |
2016 |
|
rs7895833
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The Gender Association of the SIRT1 rs7895833 Polymorphism with Pediatric Obesity: A 3-Year Panel Study.
|
28118644 |
2016 |
|
rs4994
|
|
|
0.020 |
GeneticVariation |
BEFREE |
In this study, we aimed to investigate the association of W64R polymorphism of the β3-adrenergic receptor gene (β-3AR) with childhood obesity and related pathologies.
|
25800470 |
2015 |
|
rs7895833
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The aim of this study was to investigate the association between childhood obesity and SIRT1 gene polymorphisms regarding rs7895833 A > G in the promoter region, rs7069102 C > G in intron 4, and rs2273773 C > T in exon 5 using PCR-CTPP method in 120 obese and 120 normal weight children.
|
25233986 |
2015 |
|
rs6232
|
|
|
0.020 |
GeneticVariation |
BEFREE |
This meta-analysis confirmed the association of PCSK1 SNPs with obesity and provides the first evidence that the association between PCSK1 rs6232 and obesity is stronger for childhood obesity than for adult obesity.
|
25355447 |
2014 |
|
rs149106723
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Compared with NMU-25, NMS had a significantly reduced maximum response in saphenous vein, and the Arg165Trp variant of NMU-25, associated with childhood-onset obesity, was without effect.
|
18987052 |
2009 |
|
rs1805192
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Peroxisome proliferator-activated receptor-gamma (PPARgamma) Pro12Ala polymorphism and risk for pediatric obesity.
|
19634985 |
2009 |
|
rs1232898090
|
|
|
0.020 |
GeneticVariation |
BEFREE |
PPAR-gamma2 Pro12Ala variant, insulin resistance and plasma long-chain polyunsaturated fatty acids in childhood obesity.
|
16940242 |
2006 |
|
rs149106723
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The rare NMU Arg165Trp variant cosegregated with childhood obesity in a Czech family.
|
16984985 |
2006 |