Disease: Lupus Erythematosus, Systemic
Source: ALL
Variant Gene DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Num. diseases
rs7848647
TNFSF15
0.732 0.320 9 114806766 upstream gene variant T/C snv 0.74 13
rs878859113
CD24
0.763 0.360 6 106971734 missense variant G/A snv 0.35 11
rs9271366 0.807 0.240 6 32619077 intergenic variant G/A snv 0.86 9
rs1217691063
MTHFR
0.330 0.920 1 11796309 missense variant A/G snv 4.0E-06 7.0E-06 614
rs1801274
FCGR2A
0.597 0.800 1 161509955 missense variant A/C;G snv 4.0E-06; 0.48 46
rs4986790
TLR4
0.438 0.800 9 117713024 missense variant A/G;T snv 6.1E-02; 4.0E-06 223
rs12720356
TYK2
0.752 0.360 19 10359299 missense variant A/C;G snv 6.1E-02; 4.0E-06 12
rs2910164
MIR3142HG ; MIR146A
0.447 0.880 5 160485411 mature miRNA variant C/G snv 0.71; 4.1E-06 0.70 193
rs1188383936
F2
0.524 0.760 11 46725976 missense variant C/T snv 8.0E-06 102
rs352140
TLR9
0.630 0.680 3 52222681 synonymous variant C/A;G;T snv 2.0E-05; 0.49 42
rs121917864
TLR2
0.645 0.520 4 153704936 missense variant C/T snv 8.8E-05 9.8E-05 31
rs5029941
TNFAIP3
1.000 0.080 6 137874923 missense variant C/T snv 1.2E-03 5.6E-03 2
rs35018800
TYK2
0.790 0.160 19 10354167 missense variant G/A snv 4.6E-03 4.9E-03 9
rs5743708
TLR2
0.525 0.800 4 153705165 missense variant G/A snv 1.7E-02 1.8E-02 98
rs34536443
TYK2
0.667 0.400 19 10352442 missense variant G/C snv 2.7E-02 2.8E-02 25
rs2032582
ABCB1
0.538 0.800 7 87531302 missense variant A/C;T snv 0.54; 3.8E-02 97
rs4986791
TLR4
0.456 0.840 9 117713324 missense variant C/T snv 5.7E-02 4.9E-02 182
rs763780
IL17F
0.531 0.720 6 52236941 missense variant T/C snv 6.7E-02 6.6E-02 87
rs1127354
ITPA
0.667 0.400 20 3213196 missense variant C/A;G snv 7.5E-02 26
rs1800629
TNF
0.472 0.920 6 31575254 upstream gene variant G/A snv 0.12 0.14 169
rs3746444
MIR499A ; MIR499B ; MYH7B ; LOC107985393
0.514 0.760 20 34990448 mature miRNA variant A/G snv 0.20 0.19 105
rs1805087
MTR
0.496 0.800 1 236885200 missense variant A/G snv 0.20 0.21 135
rs731236
VDR
0.542 0.760 12 47844974 synonymous variant A/G snv 0.33 0.34 81
rs1051792
MICA
0.851 0.240 6 31411200 missense variant G/A snv 0.34 0.35 5
rs721917
SFTPD
0.752 0.360 10 79946568 missense variant A/G snv 0.47 0.42 14