APP, amyloid beta precursor protein, 351

N. diseases: 485; N. variants: 114
Source: ALL
Disease Type Disease Class Semantic Type N. genes d N. SNPs d Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
CUI: C1332655
Disease: Complement component 3 deficiency
Complement component 3 deficiency 		disease Disease or Syndrome 6 1 0.010 None 1.000 1 2017 2017
CUI: C4703620
Disease: Decreased level of GABA in serum
Decreased level of GABA in serum 		phenotype Finding 6 0.100 None 0
CUI: C0333227
Disease: Microembolus
Microembolus 		disease Cardiovascular Diseases Acquired Abnormality 7 0.010 None 1.000 1 2014 2014
CUI: C0234509
Disease: Finger Agnosia
Finger Agnosia 		phenotype Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms Finding 7 0.100 None 0
CUI: C0338630
Disease: Senile Paranoid Dementia
Senile Paranoid Dementia 		disease Nervous System Diseases; Mental Disorders Mental or Behavioral Dysfunction 8 0.300 None 1.000 1 2012 2012
CUI: C0751156
Disease: FRAXA Syndrome
FRAXA Syndrome 		disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases Disease or Syndrome 8 1 0.300 None 1.000 1 2011 2011
CUI: C1853934
Disease: Deposits immunoreactive to beta-amyloid protein
Deposits immunoreactive to beta-amyloid protein 		phenotype Finding 8 0.100 None 0
CUI: C2931784
Disease: Amyloid angiopathy
Amyloid angiopathy 		disease Nutritional and Metabolic Diseases; Nervous System Diseases; Cardiovascular Diseases Disease or Syndrome 9 3 0.030 None 1.000 3 1 1998 2019
CUI: C0338657
Disease: Age-associated memory impairment
Age-associated memory impairment 		disease Disease or Syndrome 9 0.010 None 1.000 1 1997 1997
CUI: C0349081
Disease: Dementia in Parkinson's disease
Dementia in Parkinson's disease 		disease Disease or Syndrome 9 2 0.010 None 1.000 1 2018 2018
CUI: C1865903
Disease: Long-tract signs
Long-tract signs 		phenotype Finding 9 0.100 None 0
CUI: C0234544
Disease: Todd Paralysis
Todd Paralysis 		phenotype Pathological Conditions, Signs and Symptoms; Nervous System Diseases Sign or Symptom 10 0.300 None 1.000 5 2005 2017
CUI: C0154038
Disease: Benign neoplasm of thyroid gland
Benign neoplasm of thyroid gland 		disease Neoplasms; Endocrine System Diseases Neoplastic Process 10 4 0.010 None 1.000 1 2008 2008
CUI: C0333101
Disease: Microaneurysm
Microaneurysm 		disease Cardiovascular Diseases Disease or Syndrome 10 0.010 None 1.000 1 2015 2015
CUI: C0553692
Disease: Brain hemorrhage
Brain hemorrhage 		phenotype Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases Pathologic Function 10 0.300 strong 1.000 1 2010 2010
CUI: C1281300
Disease: Vascular degeneration
Vascular degeneration 		disease Cardiovascular Diseases Disease or Syndrome 10 1 0.010 None 1.000 1 2005 2005
CUI: C1861735
Disease: Dementia, familial Danish
Dementia, familial Danish 		disease Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases; Mental Disorders; Otorhinolaryngologic Diseases Disease or Syndrome 10 1 0.010 None 1.000 1 2012 2012
CUI: C0262376
Disease: anxiety generalized
anxiety generalized 		disease Behavior and Behavior Mechanisms Mental or Behavioral Dysfunction 11 0.010 None 1.000 1 2013 2013
CUI: C0751157
Disease: FRAXE Syndrome
FRAXE Syndrome 		disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases Disease or Syndrome 11 2 0.300 None 1.000 1 2011 2011
CUI: C0205858
Disease: General Paralysis
General Paralysis 		disease Infections; Nervous System Diseases Disease or Syndrome 12 3 0.010 None 1.000 1 2010 2010
CUI: C0233407
Disease: Disorientation
Disorientation 		phenotype Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms Sign or Symptom 12 0.010 None 1.000 1 2009 2009
CUI: C0393911
Disease: Pure Autonomic Failure
Pure Autonomic Failure 		disease Nervous System Diseases Disease or Syndrome 12 3 0.010 None 1.000 1 1 2008 2008
CUI: C0751230
Disease: Hypothalamic Dysfunction Syndromes
Hypothalamic Dysfunction Syndromes 		disease Nervous System Diseases Disease or Syndrome 12 0.010 None 1.000 1 2014 2014
CUI: C0521175
Disease: Neuropil Threads
Neuropil Threads 		disease Acquired Abnormality 13 0.020 None 1.000 2 2001 2019
CUI: C0029810
Disease: Other specified iron deficiency anemias
Other specified iron deficiency anemias 		disease Nutritional and Metabolic Diseases; Hemic and Lymphatic Diseases Disease or Syndrome 13 0.200 None 1.000 1 2008 2008