|
Anxiety
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways.
|
29942085 |
2018 |
|
Intelligence
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.
|
29844566 |
2018 |
|
Waist-Hip Ratio
|
0.100 |
GeneticVariation
|
phenotype |
GWASDB |
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution.
|
20935629 |
2010 |
|
Waist-Hip Ratio
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution.
|
20935629 |
2010 |
|
Waist-Hip Ratio
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry.
|
30239722 |
2019 |
|
Blood Protein Measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Co-regulatory networks of human serum proteins link genetics to disease.
|
30072576 |
2018 |
|
Diverticular Diseases
|
0.100 |
GeneticVariation
|
group |
GWASCAT |
Genome-wide association analyses identify 39 new susceptibility loci for diverticular disease.
|
30177863 |
2018 |
|
Obesity
|
0.060 |
GeneticVariation
|
disease |
BEFREE |
Genetic analysis of adiponectin and obesity in Hispanic families: the IRAS Family Study.
|
15843989 |
2005 |
|
Obesity
|
0.060 |
GeneticVariation
|
disease |
BEFREE |
Genetic mapping of a 17q chromosomal region linked to obesity phenotypes in the IRAS family study.
|
16520807 |
2006 |
|
Obesity
|
0.060 |
GeneticVariation
|
disease |
BEFREE |
Analysis of FTO gene variants with measures of obesity and glucose homeostasis in the IRAS Family Study.
|
19322589 |
2009 |
|
Obesity
|
0.060 |
GeneticVariation
|
disease |
BEFREE |
Association of proopiomelanocortin gene polymorphisms with obesity in the IRAS family study.
|
16222047 |
2005 |
|
Arteriosclerosis
|
0.030 |
GeneticVariation
|
disease |
BEFREE |
We evaluated data from the Insulin Resistance Atherosclerosis Study (IRAS Exam I, 1992-1994).
|
14594783 |
2003 |
|
Atherosclerosis
|
0.030 |
GeneticVariation
|
disease |
BEFREE |
We evaluated data from the Insulin Resistance Atherosclerosis Study (IRAS Exam I, 1992-1994).
|
14594783 |
2003 |
|
Malignant neoplasm of lung
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Interestingly, in light smokers, NISCH methylation was present in 69% of patients with lung cancer and absent in those without disease.
|
23503203 |
2013 |
|
Alzheimer Disease, Late Onset
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
In the application to the real datasets, DCL identified rs6784615, located on the NISCH gene, and rs10824310, located on the PRKG1 gene, as direct causes of late onset Alzheimer's disease (LOAD) development.
|
28363452 |
2017 |
|
Carcinoma of lung
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Interestingly, in light smokers, NISCH methylation was present in 69% of patients with lung cancer and absent in those without disease.
|
23503203 |
2013 |
|
Primary malignant neoplasm of lung
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Interestingly, in light smokers, NISCH methylation was present in 69% of patients with lung cancer and absent in those without disease.
|
23503203 |
2013 |
|
Malignant neoplasm of breast
|
0.400 |
Biomarker
|
disease |
BEFREE |
The significant differences in the expression of Nischarin between: i) Cancer tissue and noncancerous tissue and ii) patients with and without lymph node metastasis, suggested that Nischarin may have a significant role in tumor occurrence and metastasis of breast cancer.
|
25695373 |
2015 |
|
Malignant neoplasm of breast
|
0.400 |
Biomarker
|
disease |
BEFREE |
Our study aimed to analyze the association between Nischarin expression and clinical features of breast cancer patients, and further investigate the role of Nischarin in breast cancer cells apoptosis, migration and invasion.
|
28131840 |
2017 |
|
Malignant neoplasm of breast
|
0.400 |
Biomarker
|
disease |
BEFREE |
We subsequently described a role for Nischarin in breast cancer, in which it is frequently underexpressed.
|
31525254 |
2020 |
|
Malignant neoplasm of breast
|
0.400 |
Biomarker
|
disease |
BEFREE |
Exosomes from Nischarin-Expressing Cells Reduce Breast Cancer Cell Motility and Tumor Growth.
|
30635277 |
2019 |
|
Malignant neoplasm of breast
|
0.400 |
Biomarker
|
disease |
BEFREE |
Furthermore, we discuss data illustrating a novel role of Nischarin as a tumor suppressor in breast cancer.
|
26392073 |
2015 |
|
Malignant neoplasm of breast
|
0.400 |
Biomarker
|
disease |
BEFREE |
Nischarin (NISCH) is a cytoplasmic protein known to serve an inhibitory role in breast cancer cell apoptosis, migration and invasion.
|
30651848 |
2019 |
|
Malignant neoplasm of breast
|
0.400 |
Biomarker
|
disease |
CTD_human |
In summary, this project provides further clarity concerning the function of Malat1, specifically in breast cancer, while also indicating that the Nischarin expression context is an important factor in the determining how Malat1 activity is governed in breast cancer.
|
29912916 |
2018 |
|
Malignant neoplasm of breast
|
0.400 |
Biomarker
|
disease |
BEFREE |
These experiments demonstrate an important role of Nischarin in regulating cell attachment, which adds to our understanding of the early events of the metastatic process in breast cancer.
|
29415725 |
2018 |