|
Obesity
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
A co-twin-control study that allows full control of genetic influence showed that only obesity was significantly associated with higher CRP levels: Odds ratios (95% confidence intervals) were 1.23 (1.04,1.46) for 1 kg/m(2) increase in body mass index and 1.12 (1.03,1.22) for 1% increased in total body fat, respectively.
|
23360434 |
2013 |
|
Obesity
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
The association of the CRP SNPs with endometrial cancer risk and their modification on the association between obesity and endometrial cancer risk were evaluated.
|
18383516 |
2008 |
|
Obesity
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Interactions between two previously studied VDR polymorphisms (rs7968585 and rs2239179) and 25OHD concentrations on metabolic and cardiovascular disease-related outcomes such as obesity- (body mass index, waist circumference, waist-hip ratio (WHR)), cardiovascular- (systolic and diastolic blood pressure), lipid- (high- and low-density lipoprotein, triglycerides, total cholesterol), inflammatory- (C-reactive protein, fibrinogen, insulin growth factor-1, tissue plasminogen activator) and diabetes- (glycated haemoglobin) related markers were examined in the 1958 British Birth cohort (n up to 5160).
|
24582179 |
2014 |
|
Obesity
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Obesity and COC use were associated with alterations in lipid and inflammatory cardiometabolic parameters, particularly increased CRP levels and decreased HDL-c, which are considered markers of cardiovascular disease (CVD) risk.
|
29033897 |
2017 |
|
Obesity
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Boys who carry the GG genotype of CRP +2147 A/G and the CC genotype of IL-6R rs2229238 C/T have a greater risk of having abnormal BW, BMI, WC, HC, BF and WHtR and of developing obesity than individuals who do not have these genotypes.
|
20856253 |
2011 |
|
Obesity
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
For 334 normal weight (20 < BMI < or = 25 kg/m2) and 334 obese (BMI > 30 kg/m2) subjects matched by age and sex originating from the population-based EPIC-Potsdam Study, recalled weight change from age 25 to study enrollment was determined, the IL-6 g.-174G>C promoter polymorphism was defined, and plasma concentrations of IL-6 and C-reactive protein were measured.
|
16493118 |
2006 |
|
Obesity
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Effect of FTO rs9930506 on obesity and interaction of the gene variants with dietary protein and vitamin E on C-reactive protein levels in multi-ethnic Malaysian adults.
|
30141234 |
2018 |
|
Obesity
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
The current results suggest that central obesity may play a major role in lung function, and these effects were modified significantly by the polymorphisms for CRP gene.
|
21790705 |
2011 |
|
Obesity
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
We investigated whether a 1-year intensive lifestyle intervention (ILI) for weight loss would avert the unfavorable cardiometabolic effects associated with GCKR Leu446Pro when compared with a diabetes mellitus support and education arm in overweight/obese individuals with type 2 diabetes mellitus with triglyceride (n=3214) and CRP (n=1411) data participating in a randomized lifestyle intervention study for weight loss, Action for Health in Diabetes Mellitus (Look AHEAD).
|
26578543 |
2016 |
|
Obesity
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
In the overweight/obese subjects, rs1800206 was also significant associated with CRP level (P<0.01).
|
24599720 |
2015 |
|
Obesity
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Obese teachers had lower intakes of anti-inflammatory nutrients (vitamin B-6, vitamin A and zinc)/food (onion) compared with non-obese teachers (p<0.05) and obesity was significantly associated with CRP (Odd ratio (OR)=5.5, 95% Confidence interval (CI) 1.2-24.1, p=0.02).
|
29222885 |
2019 |
|
Obesity
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
The aim of this study was to investigate the associations of ICAM-1 and VCAM-1 gene variants with obesity and to investigate the associations between these genetic polymorphisms and CRP, UA, and WBC count.
|
27853845 |
2017 |
|
Obesity
|
0.600 |
Biomarker
|
disease |
BEFREE |
In this cohort, mean (SD) habitual sleep duration based on self-report was 7.6 (1.6) h and mean sleep duration by polysomnography (PSG) on the night prior to blood sampling was 6.2 (1.3) h. After adjusting for obesity and apnea severity, each additional hour of habitual sleep duration was associated with an 8% increase in C-reactive protein (CRP) levels (P=0.004) and 7% increase in interleukin-6 (IL-6) levels (P=0.0003).
|
19238807 |
2009 |
|
Obesity
|
0.600 |
Biomarker
|
disease |
BEFREE |
Hypomagnesemia (relative risk [RR] 2.27), age ≥70 (RR 1.74), proteinuria (RR 1.80), smoking (RR 21.12), C-reactive protein (RR 1.34), abdominal obesity (RR 3.92), and hypertension (RR 2.14) were predictors of ED.
|
28280316 |
2017 |
|
Obesity
|
0.600 |
Biomarker
|
disease |
BEFREE |
The aim of the study was to verify whether IFI30, CD163, CXCL9 and TSLP gene polymorphisms contribute to explain the inter-individual variability of the inflammatory profile of obesity assessed by plasma high-sensitivity CRP concentrations.
|
22178353 |
2012 |
|
Obesity
|
0.600 |
Biomarker
|
disease |
BEFREE |
It is unknown whether the co-presence of obesity and loneliness is associated with additional risk for clinically elevated CRP.
|
30439985 |
2018 |
|
Obesity
|
0.600 |
Biomarker
|
disease |
BEFREE |
C-Reactive Protein (CRP) and Leptin Receptor in Obesity: Binding of Monomeric CRP to Leptin Receptor.
|
29910808 |
2018 |
|
Obesity
|
0.600 |
Biomarker
|
disease |
BEFREE |
The objective of the study was to explore in a population-based sample whether the relation between leptin and CRP is independent of obesity level and whether genetic causes of CRP elevation contribute to leptin levels.
|
17878255 |
2007 |
|
Obesity
|
0.600 |
Biomarker
|
disease |
BEFREE |
The urinary CRP and 8-isoprostane significantly correlated with the obesity measures (body mass index, waist circumference, and waist-to- height ratio) and ET-1, inflammatory, and oxidative markers.
|
31737180 |
2019 |
|
Obesity
|
0.600 |
Biomarker
|
disease |
BEFREE |
Systemic CRP concentrations are affected by periodontitis and obesity in men.
|
31343076 |
2019 |
|
Obesity
|
0.600 |
Biomarker
|
disease |
BEFREE |
Finally, most of the well-known (i.e., blood pressure, heart rate, waist to hip, triglycerides, and HDL-C) and novel CVD risk factors [i.e., inflammation markers (C-reactive protein, leukocytes, and chemoattractant protein-1), fibrinogen, and glucose homeostasis (i.e., insulin resistance, and glycated hemoglobin)] are substantially (<i>p</i> < 0.0001) altered in severe-obese-LH: 0-2 vs overweight-LH: 0-2, pointing to the fact that obesity leads to worsen the CVD/T2D risk factor profile.
|
29951035 |
2018 |
|
Obesity
|
0.600 |
Biomarker
|
disease |
BEFREE |
We studied how CRP, ferritin and albumin change following LSG surgery in relation to obesity, metabolic syndrome (MetS) ATPIII risk components and diabetes mellitus (DM).
|
29051034 |
2018 |
|
Obesity
|
0.600 |
Biomarker
|
disease |
BEFREE |
And CRP and its combination with obesity and hypertension were associated with increased risk of T2DM.
|
30872696 |
2019 |
|
Obesity
|
0.600 |
Biomarker
|
disease |
BEFREE |
PWS presented similar percentage of body fat (%), lower body mass index (BMI) z-scores, insulin resistance, triglycerides, MetS severity, C-reactive protein (CRP), tumor necrosis factor-α (TNF-α) and MVPA and higher high-density lipoprotein (HDL) and adiponectin (ADP) than OB.
|
29975666 |
2018 |
|
Obesity
|
0.600 |
Biomarker
|
disease |
BEFREE |
Flavonoid intake is inversely associated with obesity and C-reactive protein, a marker for inflammation, in US adults.
|
28504712 |
2017 |