DSG3, desmoglein 3, 1830

N. diseases: 78; N. variants: 0
Disease: Pemphigus ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0030807
Disease: Pemphigus
Pemphigus 		0.100 Biomarker disease BEFREE Among these, two pathogenic T cell clones induced anti-Dsg3 IgG production and the development of a pemphigus phenotype when adoptively transferred with unprimed B cells from Dsg3(-/-) mice. 19155523 2009
CUI: C0030807
Disease: Pemphigus
Pemphigus 		0.100 Biomarker disease BEFREE Alternatively, immunization with a combination of dsg3 protein along with other proteins might be necessary to induce pemphigus disease in adult mice. 12653831 2003
CUI: C0030807
Disease: Pemphigus
Pemphigus 		0.100 Biomarker disease BEFREE Dsg3 was the commonest positive substrate in pemphigus group (86%) with 100% sensitivity. 31211701 2019
CUI: C0030807
Disease: Pemphigus
Pemphigus 		0.100 Biomarker disease BEFREE Pemphigus is an autoimmune blistering disease targeting the desmosomal proteins desmoglein (Dsg) 1 and Dsg3. 31057535 2019
CUI: C0030807
Disease: Pemphigus
Pemphigus 		0.100 Biomarker disease BEFREE Pemphigus is a life-threatening blistering disorder of the skin and mucous membranes caused by pathogenic autoantibodies to desmosomal adhesion proteins desmoglein 3 (Dsg3) and Dsg1. 15841178 2005