|
Breast Carcinoma
|
0.600 |
GenomicAlterations
|
disease |
CGI |
|
|
|
|
Malignant neoplasm of breast
|
0.560 |
GenomicAlterations
|
disease |
CGI |
|
|
|
|
Neoplasm of uncertain or unknown behavior of breast
|
0.300 |
GenomicAlterations
|
disease |
CGI |
|
|
|
|
Breast adenocarcinoma
|
0.300 |
GenomicAlterations
|
disease |
CGI |
|
|
|
|
Liver carcinoma
|
0.340 |
GeneticVariation
|
disease |
BEFREE |
Through hybridization with known oncogene probes, the transforming gene in one hepatoma was found to be the human hst gene.
|
2824415 |
1987 |
|
Malignant neoplasm of stomach
|
0.040 |
Biomarker
|
disease |
BEFREE |
The hst gene was originally identified as a transforming gene in DNAs from human stomach cancers and from a noncancerous portion of stomach mucosa by DNA-mediated transfection assay using NIH3T3 cells. cDNA clones of hst were isolated from the cDNA library constructed from poly(A)+ RNA of a secondary transformant induced by the DNA from a stomach cancer.
|
2953031 |
1987 |
|
Malignant neoplasm of stomach
|
0.040 |
AlteredExpression
|
disease |
BEFREE |
The hst gene was also responsible for acquisition of the transforming activity in DNA samples from 2 other stomach cancers and one colon cancer.
|
3108211 |
1987 |
|
Stomach Carcinoma
|
0.030 |
Biomarker
|
disease |
BEFREE |
The hst gene was originally identified as a transforming gene in DNAs from human stomach cancers and from a noncancerous portion of stomach mucosa by DNA-mediated transfection assay using NIH3T3 cells. cDNA clones of hst were isolated from the cDNA library constructed from poly(A)+ RNA of a secondary transformant induced by the DNA from a stomach cancer.
|
2953031 |
1987 |
|
Malignant tumor of colon
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
The hst gene was also responsible for acquisition of the transforming activity in DNA samples from 2 other stomach cancers and one colon cancer.
|
3108211 |
1987 |
|
Liver neoplasms
|
0.010 |
GeneticVariation
|
group |
BEFREE |
Through hybridization with known oncogene probes, the transforming gene in one hepatoma was found to be the human hst gene.
|
2824415 |
1987 |
|
Acute leukemia
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Five clones, containing the genomic hst gene, were isolated from a human cosmid library constructed from leukocyte DNA from a patient with acute leukemia.
|
3030292 |
1987 |
|
Colon Carcinoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
The hst gene was also responsible for acquisition of the transforming activity in DNA samples from 2 other stomach cancers and one colon cancer.
|
3108211 |
1987 |
|
Liver carcinoma
|
0.340 |
GeneticVariation
|
disease |
BEFREE |
Co-amplification of integrated hepatitis B virus DNA and transforming gene hst-1 in a hepatocellular carcinoma.
|
2856253 |
1988 |
|
Malignant Neoplasms
|
0.080 |
GeneticVariation
|
group |
BEFREE |
Human HST1 (HSTF1) gene maps to chromosome band 11q13 and coamplifies with the INT2 gene in human cancer.
|
3290903 |
1988 |
|
Neoplasm Metastasis
|
0.070 |
Biomarker
|
phenotype |
BEFREE |
The hst-1 gene was amplified in eight (42.1%) of the nineteen esophageal squamous cell carcinomas and in all four metastatic tumors of lymph nodes.
|
3136110 |
1988 |
|
Carcinoma
|
0.060 |
AlteredExpression
|
group |
BEFREE |
Amplification of the hst-1 gene in human esophageal carcinomas.
|
3136110 |
1988 |
|
Primary malignant neoplasm
|
0.060 |
GeneticVariation
|
group |
BEFREE |
Human HST1 (HSTF1) gene maps to chromosome band 11q13 and coamplifies with the INT2 gene in human cancer.
|
3290903 |
1988 |
|
Squamous cell carcinoma
|
0.040 |
Biomarker
|
disease |
BEFREE |
The hst-1 gene was amplified in eight (42.1%) of the nineteen esophageal squamous cell carcinomas and in all four metastatic tumors of lymph nodes.
|
3136110 |
1988 |
|
Malignant neoplasm of stomach
|
0.040 |
Biomarker
|
disease |
BEFREE |
The human HST1 gene, previously designated the hst gene, and now assigned the name HSTF1 for heparin-binding secretory transforming factor in human gene nomenclature, was originally identified as a transforming gene in DNAs from human stomach cancers by transfection assay with mouse NIH 3T3 cells.
|
3290903 |
1988 |
|
Malignant neoplasm of stomach
|
0.040 |
Biomarker
|
disease |
BEFREE |
Here, cosmid clones containing the hst gene were isolated directly from normal human leukocyte DNA and from T361-2nd-1 cells, a secondary transformant of NIH3T3 cells induced by transfection of DNA from a stomach cancer.
|
2895649 |
1988 |
|
Esophageal carcinoma
|
0.040 |
Biomarker
|
disease |
BEFREE |
Coamplification of the hst-1 and c-erbB-1 gene was found in one case of esophageal carcinoma.
|
3136110 |
1988 |
|
Colorectal Carcinoma
|
0.030 |
GeneticVariation
|
disease |
BEFREE |
However, no amplification of the hst-1 gene was detected in gastric and colorectal carcinomas.
|
3136110 |
1988 |
|
Stomach Carcinoma
|
0.030 |
Biomarker
|
disease |
BEFREE |
Here, cosmid clones containing the hst gene were isolated directly from normal human leukocyte DNA and from T361-2nd-1 cells, a secondary transformant of NIH3T3 cells induced by transfection of DNA from a stomach cancer.
|
2895649 |
1988 |
|
leukemia
|
0.020 |
GeneticVariation
|
disease |
BEFREE |
Restriction map of the hst gene from normal leukocyte DNA was identical with that from leukocyte DNA of a leukemia patient, while the hst gene from T361-2nd-1 cells was rearranged at the 168th nucleotide upstream of the TATA box.
|
2895649 |
1988 |
|
Childhood Leukemia
|
0.020 |
GeneticVariation
|
disease |
BEFREE |
Restriction map of the hst gene from normal leukocyte DNA was identical with that from leukocyte DNA of a leukemia patient, while the hst gene from T361-2nd-1 cells was rearranged at the 168th nucleotide upstream of the TATA box.
|
2895649 |
1988 |