IFNG, interferon gamma, 3458

N. diseases: 167; N. variants: 1
Source: CURATED ×
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0001175
Disease: Acquired Immunodeficiency Syndrome
Acquired Immunodeficiency Syndrome 		0.320 Biomarker group CTD_human Effect of zidovudine therapy in patients with HIV infection on endogenous interferon plasma levels and the hepatic cytochrome P450 enzyme system. 9612607 1998
CUI: C0702169
Disease: Acrania
Acrania 		0.300 Therapeutic disease CTD_human Valproic acid-induced fetal malformations are reduced by maternal immune stimulation with granulocyte-macrophage colony-stimulating factor or interferon-gamma. 17075842 2006
CUI: C0023487
Disease: Acute Promyelocytic Leukemia
Acute Promyelocytic Leukemia 		0.330 Biomarker disease CTD_human Inorganic arsenic represses interleukin-17A expression in human activated Th17 lymphocytes. 22617429 2012
CUI: C0857501
Disease: Acute schizophrenia
Acute schizophrenia 		0.310 Biomarker disease PSYGENET Roles of interferon-gamma and its target genes in schizophrenia: Proteomics-based reverse genetics from mouse to human. 22623148 2012
CUI: C0162309
Disease: Adrenoleukodystrophy
Adrenoleukodystrophy 		0.320 Biomarker disease CTD_human Adreno-leukodystrophy: oxidative stress of mice and men. 16319717 2005
CUI: C1527231
Disease: Adrenomyeloneuropathy
Adrenomyeloneuropathy 		0.300 Biomarker disease CTD_human Adreno-leukodystrophy: oxidative stress of mice and men. 16319717 2005
CUI: C0023493
Disease: Adult T-Cell Lymphoma/Leukemia
Adult T-Cell Lymphoma/Leukemia 		0.320 Biomarker disease CTD_human "The combination of arsenic, interferon-alpha, and zidovudine restores an ""immunocompetent-like"" cytokine expression profile in patients with adult T-cell leukemia lymphoma." 23962110 2013
CUI: C1527304
Disease: Allergic Reaction
Allergic Reaction 		0.300 Biomarker phenotype CTD_human Exogenous type-1 cytokines modulate mercury-induced hyper-IgE in the rat. 10886234 2000
CUI: C1527304
Disease: Allergic Reaction
Allergic Reaction 		0.300 Therapeutic phenotype CTD_human Exogenous type-1 cytokines modulate mercury-induced hyper-IgE in the rat. 10886234 2000
CUI: C1527304
Disease: Allergic Reaction
Allergic Reaction 		0.300 Biomarker phenotype CTD_human Expansion of CD4(+) CD25(+) and CD25(-) T-Bet, GATA-3, Foxp3 and RORγt cells in allergic inflammation, local lung distribution and chemokine gene expression. 21625544 2011
CUI: C1527304
Disease: Allergic Reaction
Allergic Reaction 		0.300 Therapeutic phenotype CTD_human Expansion of CD4(+) CD25(+) and CD25(-) T-Bet, GATA-3, Foxp3 and RORγt cells in allergic inflammation, local lung distribution and chemokine gene expression. 21625544 2011
CUI: C0002152
Disease: Alloxan Diabetes
Alloxan Diabetes 		0.300 Biomarker disease CTD_human Prevention and treatment of diabetes with resveratrol in a non-obese mouse model of type 1 diabetes. 21340626 2011
CUI: C0002874
Disease: Aplastic Anemia
Aplastic Anemia 		0.900 Biomarker disease GENOMICS_ENGLAND Homozygosis for (12) CA repeats in the first intron of the human IFN-gamma gene is significantly associated with the risk of aplastic anaemia in Caucasian population. 15327519 2004
CUI: C0002874
Disease: Aplastic Anemia
Aplastic Anemia 		0.900 Biomarker disease CTD_human
CUI: C0348890
Disease: Aplastic anemia, idiopathic
Aplastic anemia, idiopathic 		0.310 SusceptibilityMutation disease ORPHANET Homozygosis for (12) CA repeats in the first intron of the human IFN-gamma gene is significantly associated with the risk of aplastic anaemia in Caucasian population. 15327519 2004
CUI: C0003615
Disease: Appendicitis
Appendicitis 		0.300 Biomarker disease CTD_human Different cytokine profiles in patients with a history of gangrenous or phlegmonous appendicitis. 16367942 2006
CUI: C0003865
Disease: Arthritis, Adjuvant-Induced
Arthritis, Adjuvant-Induced 		0.300 Biomarker disease CTD_human Modulation of the oxidative stress and inflammatory cytokine response by thymoquinone in the collagen induced arthritis in Wistar rats. 22450443 2012
CUI: C0003865
Disease: Arthritis, Adjuvant-Induced
Arthritis, Adjuvant-Induced 		0.300 Biomarker disease CTD_human Heavy metal exposure reverses genetic resistance to Chlamydia-induced arthritis. 19203382 2009
CUI: C1692886
Disease: Arthritis, Bacterial
Arthritis, Bacterial 		0.300 Biomarker group CTD_human Heavy metal exposure reverses genetic resistance to Chlamydia-induced arthritis. 19203382 2009
CUI: C0971858
Disease: Arthritis, Collagen-Induced
Arthritis, Collagen-Induced 		0.300 Biomarker disease CTD_human Modulation of the oxidative stress and inflammatory cytokine response by thymoquinone in the collagen induced arthritis in Wistar rats. 22450443 2012
CUI: C0971858
Disease: Arthritis, Collagen-Induced
Arthritis, Collagen-Induced 		0.300 Biomarker disease CTD_human Heavy metal exposure reverses genetic resistance to Chlamydia-induced arthritis. 19203382 2009
CUI: C0993582
Disease: Arthritis, Experimental
Arthritis, Experimental 		0.300 Biomarker disease CTD_human Heavy metal exposure reverses genetic resistance to Chlamydia-induced arthritis. 19203382 2009
CUI: C0993582
Disease: Arthritis, Experimental
Arthritis, Experimental 		0.300 Biomarker disease CTD_human Modulation of the oxidative stress and inflammatory cytokine response by thymoquinone in the collagen induced arthritis in Wistar rats. 22450443 2012
CUI: C0003869
Disease: Arthritis, Infectious
Arthritis, Infectious 		0.300 Biomarker group CTD_human Heavy metal exposure reverses genetic resistance to Chlamydia-induced arthritis. 19203382 2009
CUI: C3891815
Disease: Arthritis, Suppurative
Arthritis, Suppurative 		0.300 Biomarker disease CTD_human Heavy metal exposure reverses genetic resistance to Chlamydia-induced arthritis. 19203382 2009