IFNG, interferon gamma, 3458

N. diseases: 167; N. variants: 1
Source: CURATED ×
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0003875
Disease: Arthritis, Viral
Arthritis, Viral 		0.300 Biomarker disease CTD_human Heavy metal exposure reverses genetic resistance to Chlamydia-induced arthritis. 19203382 2009
CUI: C1563937
Disease: Atherogenesis
Atherogenesis 		0.300 Biomarker phenotype CTD_human IFN-gamma potentiates atherosclerosis in ApoE knock-out mice. 9169506 1997
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis 		0.400 Biomarker disease CTD_human IFN-gamma potentiates atherosclerosis in ApoE knock-out mice. 9169506 1997
CUI: C0004352
Disease: Autistic Disorder
Autistic Disorder 		0.420 Biomarker disease CTD_human Elevated cytokine levels in children with autism spectrum disorder. 16360218 2006
CUI: C0241910
Disease: Autoimmune Chronic Hepatitis
Autoimmune Chronic Hepatitis 		0.360 Biomarker disease CTD_human Involvement of T helper 17 cells in D-penicillamine-induced autoimmune disease in Brown Norway rats. 21227906 2011
CUI: C0004364
Disease: Autoimmune Diseases
Autoimmune Diseases 		0.400 Biomarker group CTD_human Gold- and silver-induced murine autoimmunity--requirement for cytokines and CD28 in murine heavy metal-induced autoimmunity. 19077085 2009
CUI: C0004364
Disease: Autoimmune Diseases
Autoimmune Diseases 		0.400 Biomarker group CTD_human To further define their roles in systemic autoimmunity, IL-4 and IFN-gamma gene knockout mice were studied for susceptibility to the prototypic Th2-mediated mercury-induced autoimmunity. 9647229 1998
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder 		0.310 Biomarker disease PSYGENET Several studies have reported that changes in interferon-gamma (IFN-γ) may play an important role in the development of BD. 21728784 2012
CUI: C0006111
Disease: Brain Diseases
Brain Diseases 		0.310 Therapeutic group CTD_human Protective effects of interferon-gamma against methamphetamine-induced neurotoxicity. 18282668 2008
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.400 Biomarker disease CTD_human Defective gammadelta T-cell function and granzyme B gene polymorphism in a cohort of newly diagnosed breast cancer patients. 19446661 2009
CUI: C1704377
Disease: Bright Disease
Bright Disease 		0.300 Biomarker disease CTD_human Interferon gamma-mediated renal MHC expression in mercuric chloride-induced glomerulonephritis. 1825860 1991
CUI: C0342302
Disease: Brittle diabetes
Brittle diabetes 		0.300 Biomarker disease CTD_human Prevention and treatment of diabetes with resveratrol in a non-obese mouse model of type 1 diabetes. 21340626 2011
CUI: C0006272
Disease: Bronchiolitis Obliterans
Bronchiolitis Obliterans 		0.330 Therapeutic disease CTD_human Effect of gamma interferon on lung function of mustard gas exposed patients, after 15 years. 16137903 2006
CUI: C2350876
Disease: Bronchiolitis, Exudative
Bronchiolitis, Exudative 		0.300 Therapeutic disease CTD_human Effect of gamma interferon on lung function of mustard gas exposed patients, after 15 years. 16137903 2006
CUI: C2350988
Disease: Bronchiolitis, Proliferative
Bronchiolitis, Proliferative 		0.300 Therapeutic disease CTD_human Effect of gamma interferon on lung function of mustard gas exposed patients, after 15 years. 16137903 2006
CUI: C0018790
Disease: Cardiac Arrest
Cardiac Arrest 		0.300 Biomarker disease CTD_human Ketamine inhibits the proinflammatory cytokine-induced reduction of cardiac intracellular cAMP accumulation. 9806674 1998
CUI: C0600228
Disease: Cardiopulmonary Arrest
Cardiopulmonary Arrest 		0.300 Biomarker phenotype CTD_human Ketamine inhibits the proinflammatory cytokine-induced reduction of cardiac intracellular cAMP accumulation. 9806674 1998
CUI: C0007570
Disease: Celiac Disease
Celiac Disease 		0.400 Biomarker disease CTD_human Selected biomarkers were able to classify subjects with clear CD/non-CD status, and a subset of the biomarkers (CXCL10, GBP5, IFI27, IFNG, and UBD) showed differential expression in biopsies from subjects with no or low-grade intestinal injury that received a CD diagnosis based on biopsies taken at a later time point. 30097691 2018
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		0.300 Biomarker disease CTD_human Natural killer cells mediate severe liver injury in a murine model of halothane hepatitis. 21245496 2011
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		0.300 Biomarker disease CTD_human A pivotal involvement of IFN-gamma in the pathogenesis of acetaminophen-induced acute liver injury. 12153990 2002
CUI: C4279912
Disease: Chemically-Induced Liver Toxicity
Chemically-Induced Liver Toxicity 		0.300 Biomarker disease CTD_human Natural killer cells mediate severe liver injury in a murine model of halothane hepatitis. 21245496 2011
CUI: C4279912
Disease: Chemically-Induced Liver Toxicity
Chemically-Induced Liver Toxicity 		0.300 Biomarker disease CTD_human A pivotal involvement of IFN-gamma in the pathogenesis of acetaminophen-induced acute liver injury. 12153990 2002
CUI: C0085593
Disease: Chills
Chills 		0.300 Biomarker phenotype CTD_human Hyponatremia and other toxic effects during a phase I trial of recombinant human gamma interferon and vinblastine. 3091246 1986
CUI: C0008149
Disease: Chlamydia Infections
Chlamydia Infections 		0.360 Biomarker group CTD_human Heavy metal exposure reverses genetic resistance to Chlamydia-induced arthritis. 19203382 2009
CUI: C0009319
Disease: Colitis
Colitis 		0.400 Biomarker disease CTD_human Involvement of TACE in colon inflammation: a novel mechanism of regulation via SIRT-1 activation. 24548422 2014