IFNG, interferon gamma, 3458

N. diseases: 167; N. variants: 1
Source: CURATED ×
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0015967
Disease: Fever
Fever
0.400 Biomarker phenotype CTD_human Protective effects of interferon-gamma against methamphetamine-induced neurotoxicity. 18282668 2008
CUI: C0015967
Disease: Fever
Fever
0.400 Therapeutic phenotype CTD_human Protective effects of interferon-gamma against methamphetamine-induced neurotoxicity. 18282668 2008
CUI: C0023281
Disease: Leishmaniasis
Leishmaniasis
0.400 Biomarker disease CTD_human Circulating nitric oxide and C-reactive protein levels in Indian kala azar patients: correlation with clinical outcome. 17218153 2007
CUI: C0023281
Disease: Leishmaniasis
Leishmaniasis
0.400 Biomarker disease CTD_human Elevated levels of interferon-gamma, interleukin-10, and interleukin-6 during active disease in Indian kala azar. 16540374 2006
Fibrous skin tumor of tuberous sclerosis
0.400 Therapeutic disease CTD_human Combination of a rapamycin analog (CCI-779) and interferon-gamma is more effective than single agents in treating a mouse model of tuberous sclerosis complex. 16845661 2006
CUI: C0019163
Disease: Hepatitis B
Hepatitis B
0.400 Therapeutic disease CTD_human Interferon prevents formation of replication-competent hepatitis B virus RNA-containing nucleocapsids. 15994231 2005
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.400 Therapeutic disease CTD_human Regrowth of 5-fluorouracil-treated human colon cancer cells is prevented by the combination of interferon gamma, indomethacin, and phenylbutyrate. 10866311 2000
CUI: C0019693
Disease: HIV Infections
HIV Infections
0.400 Biomarker group CTD_human Persistent alterations in T-cell repertoire, cytokine and chemokine receptor gene expression after 1 year of highly active antiretroviral therapy. 10202824 1999
CUI: C0004364
Disease: Autoimmune Diseases
Autoimmune Diseases
0.400 Biomarker group CTD_human To further define their roles in systemic autoimmunity, IL-4 and IFN-gamma gene knockout mice were studied for susceptibility to the prototypic Th2-mediated mercury-induced autoimmunity. 9647229 1998
CUI: C0025202
Disease: melanoma
melanoma
0.400 Therapeutic disease CTD_human Clinical applications of TNF-alpha in cancer. 9794839 1998
CUI: C0036690
Disease: Septicemia
Septicemia
0.400 Biomarker disease CTD_human Ketamine inhibits the proinflammatory cytokine-induced reduction of cardiac intracellular cAMP accumulation. 9806674 1998
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis
0.400 Biomarker disease CTD_human IFN-gamma potentiates atherosclerosis in ApoE knock-out mice. 9169506 1997
CUI: C0023283
Disease: Leishmaniasis, Cutaneous
Leishmaniasis, Cutaneous
0.400 Therapeutic disease CTD_human Successful therapy of chronic, nonhealing murine cutaneous leishmaniasis with sodium stibogluconate and gamma interferon depends on continued interleukin-12 production. 9234779 1997
CUI: C0023283
Disease: Leishmaniasis, Cutaneous
Leishmaniasis, Cutaneous
0.400 Biomarker disease CTD_human Successful therapy of chronic, nonhealing murine cutaneous leishmaniasis with sodium stibogluconate and gamma interferon depends on continued interleukin-12 production. 9234779 1997
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung
0.400 Therapeutic disease CTD_human Interferon-gamma and interleukin-2 suppress the experimental metastasis of mouse renal adenocarcinoma. 7614408 1995
CUI: C0023283
Disease: Leishmaniasis, Cutaneous
Leishmaniasis, Cutaneous
0.400 Therapeutic disease CTD_human Clinical healing of antimony-resistant cutaneous or mucocutaneous leishmaniasis following the combined administration of interferon-gamma and pentavalent antimonial compounds. 8154019 1994
CUI: C0023283
Disease: Leishmaniasis, Cutaneous
Leishmaniasis, Cutaneous
0.400 Biomarker disease CTD_human Clinical healing of antimony-resistant cutaneous or mucocutaneous leishmaniasis following the combined administration of interferon-gamma and pentavalent antimonial compounds. 8154019 1994
CUI: C0023290
Disease: Leishmaniasis, Visceral
Leishmaniasis, Visceral
0.400 Therapeutic disease CTD_human [Interferon gamma as an immunological strategy for the treatment of human leishmaniasis]. 7854095 1994
CUI: C0023290
Disease: Leishmaniasis, Visceral
Leishmaniasis, Visceral
0.400 Therapeutic disease CTD_human Tumor necrosis factor (cachectin) in human visceral leishmaniasis. 1901333 1991
CUI: C0015967
Disease: Fever
Fever
0.400 Therapeutic phenotype CTD_human Hyponatremia and other toxic effects during a phase I trial of recombinant human gamma interferon and vinblastine. 3091246 1986
CUI: C0015967
Disease: Fever
Fever
0.400 Biomarker phenotype CTD_human Hyponatremia and other toxic effects during a phase I trial of recombinant human gamma interferon and vinblastine. 3091246 1986
CUI: C0019158
Disease: Hepatitis
Hepatitis
0.400 Biomarker group CTD_human Hyponatremia and other toxic effects during a phase I trial of recombinant human gamma interferon and vinblastine. 3091246 1986
CUI: C0019196
Disease: Hepatitis C
Hepatitis C
0.400 Biomarker disease CTD_human
CUI: C3714636
Disease: Pneumonitis
Pneumonitis
0.370 Biomarker disease CTD_human Expansion of CD4(+) CD25(+) and CD25(-) T-Bet, GATA-3, Foxp3 and RORγt cells in allergic inflammation, local lung distribution and chemokine gene expression. 21625544 2011
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.370 Biomarker group CTD_human Defective gammadelta T-cell function and granzyme B gene polymorphism in a cohort of newly diagnosed breast cancer patients. 19446661 2009