IL1B, interleukin 1 beta, 3553

N. diseases: 1801; N. variants: 22
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.600 Biomarker disease RGD Evaluation of the anti-myocardial ischemia effect of individual and combined extracts of Panax notoginseng and Carthamus tinctorius in rats. 23237935 2013
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.600 Biomarker disease RGD Delayed anesthetic preconditioning protects against myocardial infarction via activation of nuclear factor-κB and upregulation of autophagy. 23143013 2013
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.600 GeneticVariation disease BEFREE In contrast, CC genotype of IL-1β and GG genotype of TNF-α have protective effect against myocardial infarction. 21380730 2011
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.600 GeneticVariation disease BEFREE In addition, IL-1 and IL-6 gene polymorphisms did not affect MI at younger age (MI<40) or older age (MI>40). 21199393 2011
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.600 Biomarker disease BEFREE Fifteen haplotype-tagging single nucleotide polymorphisms (SNPs) in the IL-1α (IL1A), IL-1β (IL1B), and IL-1 receptor antagonist (IL-1RN) genes were determined in the Health 2000 survey (n = 6771) and European myocardial infarction (MI) survivors (n = 972). 20178882 2010
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.600 Biomarker disease BEFREE An association was observed between CAD and a common three-locus haplotype in the interleukin one (IL-1) cluster with P = 0.006 in all CAD cases, P = 0.01 in myocardial infarction (MI) cases and P = 0.0002 in young onset CAD cases (<50 years). 20070880 2010
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.600 Biomarker disease CTD_human Effects of carvedilol on cardiac cytokines expression and remodeling in rat with acute myocardial infarction. 16310260 2006
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.600 GeneticVariation disease LHGDN -511C/T IL-1beta gene polymorphism affects the risk of MI and ischemic stroke at young age and the response of mononuclear cells to inflammatory stimulation. 15539626 2005
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.600 Biomarker disease CTD_human Simvastatin regulates myocardial cytokine expression and improves ventricular remodeling in rats after acute myocardial infarction. 15883752 2005
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.600 GeneticVariation disease BEFREE -511C/T IL-1beta gene polymorphism affects the risk of MI and ischemic stroke at young age and the response of mononuclear cells to inflammatory stimulation. 15539626 2005
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.600 GeneticVariation disease BEFREE The IL-6C and APOE epsilon4 alleles were independently associated with a mild or moderate increased risk of MI, whilst the allele C of the IL-1beta was not independently linked to MI risk. 15336915 2004
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.600 Biomarker disease CTD_human Long-term effects of carvedilol on left ventricular function, remodeling, and expression of cardiac cytokines after large myocardial infarction in the rat. 11743230 2002
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.600 GeneticVariation disease BEFREE The IL-1 gene polymorphisms were found to play a role in the development of CAD, especially MI, in patients with CP infection. 11527622 2001