|
Obesity
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Common variants of IL6, LEPR, and PBEF1 are associated with obesity in Indian children.
|
22228719 |
2012 |
|
Obesity
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
The IL-6 G174C polymorphism was also associated obesity when using allelic comparisons, the recessive genetic model and the dominant genetic model with OR (95% CI) of 1.95 (1.37-2.77), 1.44 (1.15-1.80), and 1.36 (1.16-1.59), respectively.
|
21660081 |
2012 |
|
Obesity
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
We found that IL-1B rs1864169 and IL-6 rs1800796 polymorphisms may interact with diabetes, hypertension and obesity.
|
24782217 |
2014 |
|
Obesity
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Association between -174G>C polymorphism in the IL-6 promoter region and the risk of obesity: A meta-analysis.
|
30113463 |
2018 |
|
Obesity
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
In G/G population, the IL-6 plasma level of NWO and OB was significantly higher with respect to NW.
|
18991689 |
2008 |
|
Obesity
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
The polymorphism found in point 174 (G174C) of a promoter region of IL-6 gene affects the level of interleukin-6 expression and, consequently, may lead to obesity and correlated conditions.
|
21147639 |
2010 |
|
Obesity
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
The Objective is to investigate the relationship between IL-6 (rs1554606) polymorphism and the risk of obesity in young Saudi population.
|
24395296 |
2014 |
|
Obesity
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Indeed, subjects carrying both PPARG and IL-6 gene variants, had a clearly more favourable profile of obesity related risk factors than subjects with one variant, having Ala+/C+ carriers lower BMI (22.8 +/- 2.3 vs 24.14 +/- 1.9; f = 5.31; p < 0.005), insulin resistance (1.49 +/- 0.70 vs 2.13 +/- 0.92; f = 4.342; p = 0.038) and triglyceride levels (79.15 +/- 32.9 vs 98 +/- 6.73 mg/dl; f = 3.120; p < 0.005).
|
16029943 |
2005 |
|
Obesity
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Multivariate linear regression analysis revealed that obesity is the dominant force, thus explaining 18% and 24% of the IL-6 or CRP levels, respectively, in PCOS women.
|
15080783 |
2004 |
|
Obesity
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Composite genotype or haplotype analyses of all 3 IL6 promoter variants showed associations with type 2 diabetes (p<0.002), obesity (p<0.02), and the metabolic syndrome (p<0.01).
|
15645209 |
2005 |
|
Obesity
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
From the results of the present study, we concluded that individuals homozygous for G allele on the IL-6 gene have higher values in some parameters associated with obesity.
|
15292466 |
2004 |
|
Obesity
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Minor allele of IL-6 rs1800797polymorphism decreased the risk of obesity/overweight in allelic 0.74 (0.59-0.92), dominant 0.65 (0.49-0.85), and over-dominant 0.66 (0.51-0.87) models.
|
31472475 |
2019 |
|
Obesity
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
All PPAR SNPs were not associated with obesity and Met-S in the suburban population of Kampar, Malaysia, where only PPARα V162 and PPARγ2 T161 alleles were associated with plasma IL-6 and HOMA-IR, respectively.
|
26673968 |
2015 |
|
Obesity
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
We found a relation between G174C polymorphism in IL-6 gene and G308A in TNF-alpha gene with the occurrence of obesity.
|
20156727 |
2009 |
|
Obesity
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Interleukin-6 polymorphisms are associated with obesity and hyperglycemia in Mexican adolescents.
|
23142265 |
2013 |
|
Obesity
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
The -174 IL-6 promoter polymorphism modifies the association of obesity with IR and diabetes risk in men.
|
16988089 |
2006 |
|
Obesity
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
A polymorphism in the promoter region of the IL6 gene (-174G/C), has been previously reported to be involved in obesity and metabolic syndrome development.
|
20358354 |
2009 |
|
Obesity
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
This study investigated interactions between dietary fat intake and IL-6 polymorphisms on obesity and serum lipids in black and white South African (SA) women.
|
24962479 |
2014 |
|
Obesity
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
A promoter polymorphism in the IL6 gene is associated with obesity, altered levels of insulin sensitivity, and T2DM.
|
14680981 |
2003 |
|
Obesity
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
SNPs IL6 -174G/C and TNFalpha -308G/A are not major contributors to T2D or obesity risk in our Tunisian population.
|
20132806 |
2010 |
|
Obesity
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Obesity is most frequently associated in children with IL-6 174 C allele carriers and with IL-6 190 C allele carriers.
|
24740880 |
2014 |
|
Obesity
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Our results suggest that genetic variation in or near the IL6 locus may be involved in the etiology of obesity and osteoporosis.
|
12898289 |
2003 |
|
Obesity
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Our data show that the G allele of the -174G/C IL-6 polymorphism and obesity can be considered as risk factors for the prognosis and management of psoriasis.
|
22158445 |
2012 |
|
Obesity
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Our results suggested that the C allele of rs1800796 and the C allele of rs2069849 of IL-6 gene interaction between rs1800796 and abdominal obesity were all associated with increased OST risk.
|
31301734 |
2019 |
|
Obesity
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
The present study examined the potential association of IL-6-174 G/C polymorphism, together with obesity and smoking, with the presence of CVD in RA patients.
|
18848327 |
2009 |