|
Myocardial Infarction
|
0.490 |
GeneticVariation
|
disease |
BEFREE |
Independent association genetic studies have implicated OLR1 gene variants in myocardial infarction (MI) susceptibility.
|
15976314 |
2005 |
|
Myocardial Infarction
|
0.490 |
Biomarker
|
disease |
CTD_human |
Association of single nucleotide polymorphisms in the oxidised LDL receptor 1 (OLR1) gene in patients with acute myocardial infarction.
|
14684693 |
2003 |
|
Myocardial Infarction
|
0.490 |
Biomarker
|
disease |
BEFREE |
The lectin-like oxidized LDL receptor LOX-1 (encoded by OLR1) is believed to play a key role in atherogenesis and some reports suggest an association of OLR1 polymorphisms with myocardial infarction (MI).
|
18384690 |
2008 |
|
Myocardial Infarction
|
0.490 |
Biomarker
|
disease |
CTD_human |
These findings suggest that OLR1 or a neighboring gene linked with G501C SNP is important for the incidence of MI.
|
12646194 |
2003 |
|
Myocardial Infarction
|
0.490 |
Biomarker
|
disease |
BEFREE |
LOX-1 is increasingly viewed as a vascular disease biomarker and a potential therapeutic target in heart attack and stroke prevention.
|
18092947 |
2008 |
|
Myocardial Infarction
|
0.490 |
Biomarker
|
disease |
BEFREE |
The cardiac lectin-like oxidized low-density-lipoprotein receptor-1 is activated by oxidative stress in ischaemia-reperfusion injury, inducing apoptosis in cardiomyocytes through the deleterious NF-kB pathway, while the administration of anti-lectin-like oxidized low-density-lipoprotein receptor-1 antibody suppresses apoptosis and reduces the extent of myocardial infarction.
|
31782085 |
2020 |
|
Myocardial Infarction
|
0.490 |
SusceptibilityMutation
|
disease |
CLINVAR |
|
|
|
|
Myocardial Infarction
|
0.490 |
Biomarker
|
disease |
LHGDN |
Association of single nucleotide polymorphisms in the oxidised LDL receptor 1 (OLR1) gene in patients with acute myocardial infarction.
|
14684693 |
2003 |
|
Myocardial Infarction
|
0.490 |
GeneticVariation
|
disease |
BEFREE |
Recently, a 3'-UTR (188 C>T) SNP in the OLR1 gene has been reported to be associated with coronary artery stenosis and myocardial infarction.
|
16829343 |
2006 |
|
Myocardial Infarction
|
0.490 |
GeneticVariation
|
disease |
BEFREE |
Recently, LOX-1 gene polymorphism (G501C) was reported to be associated with myocardial infarction (MI).
|
15562935 |
2004 |
|
Myocardial Infarction
|
0.490 |
GeneticVariation
|
disease |
BEFREE |
In humans, LOX-1 gene polymorphisms were associated with increased susceptibility to myocardial infarction.
|
23935243 |
2013 |
|
Myocardial Infarction
|
0.490 |
GeneticVariation
|
disease |
BEFREE |
These findings suggest that OLR1 or a neighboring gene linked with G501C SNP is important for the incidence of MI.
|
12646194 |
2003 |
|
Heart failure
|
0.320 |
GeneticVariation
|
disease |
BEFREE |
Deletion of LOX-1 Protects against Heart Failure Induced by Doxorubicin.
|
27195769 |
2016 |
|
Heart failure
|
0.320 |
Biomarker
|
disease |
CTD_human |
Vascular and thrombogenic effects of pulmonary exposure to Libby amphibole.
|
22352330 |
2012 |
|
Heart failure
|
0.320 |
Biomarker
|
disease |
BEFREE |
In conclusion, α1-antitrypsin and lectin-like oxidized low-density-lipoprotein receptor-1 seem to represent two good markers in HF and therapeutic targets, whereas galectin-3 does not.
|
31782085 |
2020 |
|
Congestive heart failure
|
0.320 |
GeneticVariation
|
disease |
BEFREE |
Deletion of LOX-1 Protects against Heart Failure Induced by Doxorubicin.
|
27195769 |
2016 |
|
Congestive heart failure
|
0.320 |
Biomarker
|
disease |
BEFREE |
In conclusion, α1-antitrypsin and lectin-like oxidized low-density-lipoprotein receptor-1 seem to represent two good markers in HF and therapeutic targets, whereas galectin-3 does not.
|
31782085 |
2020 |
|
Congestive heart failure
|
0.320 |
Biomarker
|
disease |
CTD_human |
Vascular and thrombogenic effects of pulmonary exposure to Libby amphibole.
|
22352330 |
2012 |
|
Left-Sided Heart Failure
|
0.300 |
Biomarker
|
disease |
CTD_human |
Vascular and thrombogenic effects of pulmonary exposure to Libby amphibole.
|
22352330 |
2012 |
|
Juvenile-Onset Still Disease
|
0.300 |
Biomarker
|
disease |
CTD_human |
Gene expression signatures in polyarticular juvenile idiopathic arthritis demonstrate disease heterogeneity and offer a molecular classification of disease subsets.
|
19565504 |
2009 |
|
Heart Failure, Right-Sided
|
0.300 |
Biomarker
|
disease |
CTD_human |
Vascular and thrombogenic effects of pulmonary exposure to Libby amphibole.
|
22352330 |
2012 |
|
Myocardial Failure
|
0.300 |
Biomarker
|
disease |
CTD_human |
Vascular and thrombogenic effects of pulmonary exposure to Libby amphibole.
|
22352330 |
2012 |
|
Juvenile arthritis
|
0.300 |
Biomarker
|
disease |
CTD_human |
Gene expression signatures in polyarticular juvenile idiopathic arthritis demonstrate disease heterogeneity and offer a molecular classification of disease subsets.
|
19565504 |
2009 |
|
Juvenile psoriatic arthritis
|
0.300 |
Biomarker
|
disease |
CTD_human |
Gene expression signatures in polyarticular juvenile idiopathic arthritis demonstrate disease heterogeneity and offer a molecular classification of disease subsets.
|
19565504 |
2009 |
|
Polyarthritis, Juvenile, Rheumatoid Factor Negative
|
0.300 |
Biomarker
|
disease |
CTD_human |
Gene expression signatures in polyarticular juvenile idiopathic arthritis demonstrate disease heterogeneity and offer a molecular classification of disease subsets.
|
19565504 |
2009 |