|
Adolescent idiopathic scoliosis
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
The coexistence of copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) at a locus can result in distorted calculations of the significance in associating SNPs to disease.
|
30019117 |
2018 |
|
Breast Carcinoma
|
0.020 |
AlteredExpression
|
disease |
BEFREE |
They therefore suggest that dysregulation of APC activity, possibly through downregulation of APC7, may be associated with tumorigenesis in breast cancer.
|
15743504 |
2005 |
|
Breast Carcinoma
|
0.020 |
AlteredExpression
|
disease |
BEFREE |
SCARA3 messenger RNA (mRNA) expression was analyzed in 127 effusions (103 ovarian/peritoneal/fallopian tube carcinomas, 9 breast carcinomas, 15 malignant mesotheliomas [MM]), and 30 solid primary OCs.
|
21855113 |
2012 |
|
Carcinogenesis
|
0.010 |
AlteredExpression
|
phenotype |
BEFREE |
They therefore suggest that dysregulation of APC activity, possibly through downregulation of APC7, may be associated with tumorigenesis in breast cancer.
|
15743504 |
2005 |
|
Carcinoma
|
0.010 |
AlteredExpression
|
group |
BEFREE |
SCARA3 levels in effusions and primary carcinomas were unrelated to patient age, tumor grade, FIGO stage, residual tumor volume after surgery, response to chemotherapy, or survival (P > .05 for all).
|
21855113 |
2012 |
|
Carcinoma of lung
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Within the CSR gene set, a group of 42 v-Src inducible genes was associated with reduced disease- and metastasis-free survival in several independent patient cohorts with breast or lung cancer.
|
20152043 |
2010 |
|
Cardiomyopathy, Familial Idiopathic
|
0.010 |
Biomarker
|
disease |
BEFREE |
We aimed to explore the prevalence of polymorphisms of the HSPB7 gene in the Chinese Han population with CSR-CSA and CHF caused by DCM.
|
27441470 |
2016 |
|
Cheyne-Stokes Respiration
|
0.010 |
GeneticVariation
|
phenotype |
BEFREE |
Background The contribution of the lung or the plant gain ( PG ; ie, change in blood gases per unit change in ventilation) to Cheyne-Stokes respiration ( CSR ) in heart failure has only been hypothesized by mathematical models, but never been directly evaluated.
|
31237174 |
2019 |
|
Congestive heart failure
|
0.030 |
Biomarker
|
disease |
BEFREE |
This study investigated the association of microstructural cerebral lesions with central sleep apnea with Cheyne-Stokes-respiration (CSA-CSR) in heart failure (HF) patients and the effect of positive airway pressure therapy (PAP) of CSA-CSR on these lesions.
|
29102807 |
2018 |
|
Congestive heart failure
|
0.030 |
Biomarker
|
disease |
BEFREE |
Conclusions PG is a powerful contributor of CSR and should be evaluated together with the CG and circulation time to individualize treatments aimed at stabilizing breathing in heart failure.
|
31237174 |
2019 |
|
Congestive heart failure
|
0.030 |
Biomarker
|
disease |
BEFREE |
Our findings suggest the novel concept that the negative pattern of CSR-CSA may constitute a form of auto-resuscitation that acts as a compensatory mechanism to maintain SV in patients with severe HF.
|
30946471 |
2019 |
|
Craniosynostosis
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Here, we describe a patient whose features we would suggest represent a new FGFR2-related syndrome, craniosynostosis with XY male-to-female sex reversal or CSR.
|
26362256 |
2015 |
|
Ductal Carcinoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
The expression of APC7 was immunohistochemically investigated in 108 invasive ductal carcinomas of the breast and its relationship with clinicopathologic parameters was examined.
|
15743504 |
2005 |
|
Hand, Foot and Mouth Disease
|
0.010 |
Biomarker
|
disease |
BEFREE |
The mean relative expression levels in severe HFMD and control HFMD patients were 10.1-fold and 5.0-fold, respectively, P value <.001.We found that SCARA3 is associated with severity of HFMD, and it may be a potential prognostic marker to predict the HFMD progression in EV71 infected patients.
|
31577778 |
2019 |
|
Heart failure
|
0.030 |
Biomarker
|
disease |
BEFREE |
Conclusions PG is a powerful contributor of CSR and should be evaluated together with the CG and circulation time to individualize treatments aimed at stabilizing breathing in heart failure.
|
31237174 |
2019 |
|
Heart failure
|
0.030 |
Biomarker
|
disease |
BEFREE |
Our findings suggest the novel concept that the negative pattern of CSR-CSA may constitute a form of auto-resuscitation that acts as a compensatory mechanism to maintain SV in patients with severe HF.
|
30946471 |
2019 |
|
Heart failure
|
0.030 |
Biomarker
|
disease |
BEFREE |
This study investigated the association of microstructural cerebral lesions with central sleep apnea with Cheyne-Stokes-respiration (CSA-CSR) in heart failure (HF) patients and the effect of positive airway pressure therapy (PAP) of CSA-CSR on these lesions.
|
29102807 |
2018 |
|
Liver carcinoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
The mRNA and protein levels of CSR1 were down-regulated in human HCC cell lines and clinic HCC tissues.
|
28975986 |
2017 |
|
Malignant Childhood Neoplasm
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
In 22 childhood cancer survivors (median age: 14.8, range 6.4-21.6 years), mean GLS (- 13.83 ± 0.74% to - 15.94 ± 0.74%, p = 0.002), GCS (- 18.79 ± 1.21% to - 20.74 ± 0.84%, p = 0.027), LSR (- 0.78 ± 0.04 to - 0.88 ± 0.04 s<sup>-1</sup>, p = 0.022), and CSR (- 1.08 ± 0.07 to - 1.21 ± 0.06 s<sup>-1</sup>, p = 0.027) improved on therapy.
|
29789916 |
2018 |
|
Malignant neoplasm of breast
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
They therefore suggest that dysregulation of APC activity, possibly through downregulation of APC7, may be associated with tumorigenesis in breast cancer.
|
15743504 |
2005 |
|
Malignant neoplasm of lung
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Within the CSR gene set, a group of 42 v-Src inducible genes was associated with reduced disease- and metastasis-free survival in several independent patient cohorts with breast or lung cancer.
|
20152043 |
2010 |
|
Malignant neoplasm of prostate
|
0.040 |
AlteredExpression
|
disease |
BEFREE |
Forced expression of CSR1 in prostate cancer cell lines DU145 and PC3 resulted in a two- to threefold decrease in colony formation and a 10-fold reduction in anchorage-independent growth.
|
16436673 |
2006 |
|
Malignant neoplasm of prostate
|
0.040 |
Biomarker
|
disease |
BEFREE |
Cellular Stress Response 1 (CSR1) is a tumor suppressor gene and frequently deleted in prostate cancers.
|
29705808 |
2018 |
|
Malignant neoplasm of prostate
|
0.040 |
AlteredExpression
|
disease |
BEFREE |
Cellular stress response 1 (CSR1) is a tumor suppressor gene that was frequently down-regulated in prostate cancer.
|
28975986 |
2017 |
|
Malignant neoplasm of prostate
|
0.040 |
AlteredExpression
|
disease |
BEFREE |
Cellular stress response 1 (CSR1) is a tumor suppressor gene whose expression was frequently down-regulated in prostate cancer.
|
25956032 |
2015 |