|
Adolescent idiopathic scoliosis
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
The coexistence of copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) at a locus can result in distorted calculations of the significance in associating SNPs to disease.
|
30019117 |
2018 |
|
SCOLIOSIS, ISOLATED, SUSCEPTIBILITY TO, 3
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
The coexistence of copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) at a locus can result in distorted calculations of the significance in associating SNPs to disease.
|
30019117 |
2018 |
|
Neoplasms
|
0.080 |
Biomarker
|
group |
BEFREE |
Cellular Stress Response 1 (CSR1) is a tumor suppressor gene and frequently deleted in prostate cancers.
|
29705808 |
2018 |
|
Neoplasms
|
0.080 |
Biomarker
|
group |
BEFREE |
Cellular stress response 1 (CSR1) is a tumor suppressor gene that plays an important role in regulating cell death.
|
27148859 |
2017 |
|
Neoplasms
|
0.080 |
Biomarker
|
group |
BEFREE |
CSR1 suppresses tumor growth and metastasis of human hepatocellular carcinoma via inhibition of HPIP.
|
28975986 |
2017 |
|
Neoplasms
|
0.080 |
AlteredExpression
|
group |
BEFREE |
Cellular stress response 1 (CSR1) is a tumor suppressor gene whose expression was frequently down-regulated in prostate cancer.
|
25956032 |
2015 |
|
Neoplasms
|
0.080 |
AlteredExpression
|
group |
BEFREE |
SCARA3 levels in effusions and primary carcinomas were unrelated to patient age, tumor grade, FIGO stage, residual tumor volume after surgery, response to chemotherapy, or survival (P > .05 for all).
|
21855113 |
2012 |
|
Neoplasms
|
0.080 |
Biomarker
|
group |
BEFREE |
A clustering enrichment regime using the CSR genes and two independent breast tumor data-sets was used to identify a 42-gene aggressive tumor gene signature.
|
20152043 |
2010 |
|
Neoplasms
|
0.080 |
Biomarker
|
group |
BEFREE |
Transgenic mouse models of T(12;15)/t(8;14), including newly developed "iMyc" gene-insertion mice, will be useful in elucidating the role of these CSR factors in the progression of Myc-induced B cell tumors.
|
16815105 |
2006 |
|
Neoplasms
|
0.080 |
Biomarker
|
group |
BEFREE |
The present findings suggest that CSR1 is a potent tumor sup-pressor gene.
|
16436673 |
2006 |
|
Malignant neoplasm of prostate
|
0.040 |
Biomarker
|
disease |
BEFREE |
Cellular Stress Response 1 (CSR1) is a tumor suppressor gene and frequently deleted in prostate cancers.
|
29705808 |
2018 |
|
Malignant neoplasm of prostate
|
0.040 |
AlteredExpression
|
disease |
BEFREE |
Cellular stress response 1 (CSR1) is a tumor suppressor gene that was frequently down-regulated in prostate cancer.
|
28975986 |
2017 |
|
Malignant neoplasm of prostate
|
0.040 |
AlteredExpression
|
disease |
BEFREE |
Cellular stress response 1 (CSR1) is a tumor suppressor gene whose expression was frequently down-regulated in prostate cancer.
|
25956032 |
2015 |
|
Malignant neoplasm of prostate
|
0.040 |
AlteredExpression
|
disease |
BEFREE |
Forced expression of CSR1 in prostate cancer cell lines DU145 and PC3 resulted in a two- to threefold decrease in colony formation and a 10-fold reduction in anchorage-independent growth.
|
16436673 |
2006 |
|
Heart failure
|
0.030 |
Biomarker
|
disease |
BEFREE |
Conclusions PG is a powerful contributor of CSR and should be evaluated together with the CG and circulation time to individualize treatments aimed at stabilizing breathing in heart failure.
|
31237174 |
2019 |
|
Heart failure
|
0.030 |
Biomarker
|
disease |
BEFREE |
Our findings suggest the novel concept that the negative pattern of CSR-CSA may constitute a form of auto-resuscitation that acts as a compensatory mechanism to maintain SV in patients with severe HF.
|
30946471 |
2019 |
|
Congestive heart failure
|
0.030 |
Biomarker
|
disease |
BEFREE |
Conclusions PG is a powerful contributor of CSR and should be evaluated together with the CG and circulation time to individualize treatments aimed at stabilizing breathing in heart failure.
|
31237174 |
2019 |
|
Congestive heart failure
|
0.030 |
Biomarker
|
disease |
BEFREE |
Our findings suggest the novel concept that the negative pattern of CSR-CSA may constitute a form of auto-resuscitation that acts as a compensatory mechanism to maintain SV in patients with severe HF.
|
30946471 |
2019 |
|
Heart failure
|
0.030 |
Biomarker
|
disease |
BEFREE |
This study investigated the association of microstructural cerebral lesions with central sleep apnea with Cheyne-Stokes-respiration (CSA-CSR) in heart failure (HF) patients and the effect of positive airway pressure therapy (PAP) of CSA-CSR on these lesions.
|
29102807 |
2018 |
|
Congestive heart failure
|
0.030 |
Biomarker
|
disease |
BEFREE |
This study investigated the association of microstructural cerebral lesions with central sleep apnea with Cheyne-Stokes-respiration (CSA-CSR) in heart failure (HF) patients and the effect of positive airway pressure therapy (PAP) of CSA-CSR on these lesions.
|
29102807 |
2018 |
|
Prostate carcinoma
|
0.030 |
AlteredExpression
|
disease |
BEFREE |
Cellular stress response 1 (CSR1) is a tumor suppressor gene that was frequently down-regulated in prostate cancer.
|
28975986 |
2017 |
|
Prostate carcinoma
|
0.030 |
AlteredExpression
|
disease |
BEFREE |
Cellular stress response 1 (CSR1) is a tumor suppressor gene whose expression was frequently down-regulated in prostate cancer.
|
25956032 |
2015 |
|
Prostate carcinoma
|
0.030 |
AlteredExpression
|
disease |
BEFREE |
Forced expression of CSR1 in prostate cancer cell lines DU145 and PC3 resulted in a two- to threefold decrease in colony formation and a 10-fold reduction in anchorage-independent growth.
|
16436673 |
2006 |
|
Neoplasm Metastasis
|
0.020 |
Biomarker
|
phenotype |
BEFREE |
CSR1 suppresses tumor growth and metastasis of human hepatocellular carcinoma via inhibition of HPIP.
|
28975986 |
2017 |
|
Tumor Cell Invasion
|
0.020 |
AlteredExpression
|
phenotype |
BEFREE |
For the first time we demonstrated that CSR1 inhibited HCC cell proliferation, migration and invasion through inactivation of HPIP and its downstream PI3K/AKT signaling pathway and suggested CSR1 as a potential therapy target for HCC treatment.
|
28975986 |
2017 |