Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1514428
Disease: Primary peritoneal carcinoma
Primary peritoneal carcinoma
0.010 AlteredExpression disease BEFREE Scavenger receptor class A, member 3 (SCARA3) was previously found to be overexpressed in ovarian/primary peritoneal carcinoma (OC/PPC) compared with breast carcinoma effusions by global gene expression analysis. 21855113 2012
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.020 AlteredExpression disease BEFREE SCARA3 messenger RNA (mRNA) expression was analyzed in 127 effusions (103 ovarian/peritoneal/fallopian tube carcinomas, 9 breast carcinomas, 15 malignant mesotheliomas [MM]), and 30 solid primary OCs. 21855113 2012
CUI: C0025500
Disease: Mesothelioma
Mesothelioma
0.010 AlteredExpression disease BEFREE SCARA3 messenger RNA (mRNA) expression was analyzed in 127 effusions (103 ovarian/peritoneal/fallopian tube carcinomas, 9 breast carcinomas, 15 malignant mesotheliomas [MM]), and 30 solid primary OCs. 21855113 2012
CUI: C0007097
Disease: Carcinoma
Carcinoma
0.010 AlteredExpression group BEFREE SCARA3 levels in effusions and primary carcinomas were unrelated to patient age, tumor grade, FIGO stage, residual tumor volume after surgery, response to chemotherapy, or survival (P > .05 for all). 21855113 2012
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.080 AlteredExpression group BEFREE SCARA3 levels in effusions and primary carcinomas were unrelated to patient age, tumor grade, FIGO stage, residual tumor volume after surgery, response to chemotherapy, or survival (P > .05 for all). 21855113 2012
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.080 Biomarker group BEFREE CSR1 suppresses tumor growth and metastasis of human hepatocellular carcinoma via inhibition of HPIP. 28975986 2017
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.020 Biomarker phenotype BEFREE CSR1 suppresses tumor growth and metastasis of human hepatocellular carcinoma via inhibition of HPIP. 28975986 2017
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.080 Biomarker group BEFREE A clustering enrichment regime using the CSR genes and two independent breast tumor data-sets was used to identify a 42-gene aggressive tumor gene signature. 20152043 2010
CUI: C0040100
Disease: Thymoma
Thymoma
0.010 AlteredExpression disease BEFREE At quantitative assessment, both the radiodensity and CSR were significantly higher for thymoma compared with nonthymoma groups (<i>P</i> < .001). 31331197 2020
CUI: C0008039
Disease: Cheyne-Stokes Respiration
Cheyne-Stokes Respiration
0.010 GeneticVariation phenotype BEFREE Background The contribution of the lung or the plant gain ( PG ; ie, change in blood gases per unit change in ventilation) to Cheyne-Stokes respiration ( CSR ) in heart failure has only been hypothesized by mathematical models, but never been directly evaluated. 31237174 2019
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.080 AlteredExpression group BEFREE Cellular stress response 1 (CSR1) is a tumor suppressor gene whose expression was frequently down-regulated in prostate cancer. 25956032 2015
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.040 AlteredExpression disease BEFREE Cellular stress response 1 (CSR1) is a tumor suppressor gene whose expression was frequently down-regulated in prostate cancer. 25956032 2015
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.030 AlteredExpression disease BEFREE Cellular stress response 1 (CSR1) is a tumor suppressor gene whose expression was frequently down-regulated in prostate cancer. 25956032 2015
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.080 Biomarker group BEFREE Cellular stress response 1 (CSR1) is a tumor suppressor gene that plays an important role in regulating cell death. 27148859 2017
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.040 AlteredExpression disease BEFREE Cellular stress response 1 (CSR1) is a tumor suppressor gene that was frequently down-regulated in prostate cancer. 28975986 2017
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.030 AlteredExpression disease BEFREE Cellular stress response 1 (CSR1) is a tumor suppressor gene that was frequently down-regulated in prostate cancer. 28975986 2017
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.080 Biomarker group BEFREE Cellular Stress Response 1 (CSR1) is a tumor suppressor gene and frequently deleted in prostate cancers. 29705808 2018
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.040 Biomarker disease BEFREE Cellular Stress Response 1 (CSR1) is a tumor suppressor gene and frequently deleted in prostate cancers. 29705808 2018
CUI: C0018801
Disease: Heart failure
Heart failure
0.030 Biomarker disease BEFREE Conclusions PG is a powerful contributor of CSR and should be evaluated together with the CG and circulation time to individualize treatments aimed at stabilizing breathing in heart failure. 31237174 2019
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure
0.030 Biomarker disease BEFREE Conclusions PG is a powerful contributor of CSR and should be evaluated together with the CG and circulation time to individualize treatments aimed at stabilizing breathing in heart failure. 31237174 2019
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.010 AlteredExpression group LHGDN CSR1 suppresses tumor growth and metastasis of prostate cancer. 16436673 2006
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.020 AlteredExpression phenotype BEFREE Expression of CSR1 in PC3 cell xenografts produced a dramatic reduction (>8-fold) in tumor size, rate of invasion (0 versus 31%), and mortality (13 versus 100%). 16436673 2006
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.020 AlteredExpression phenotype BEFREE For the first time we demonstrated that CSR1 inhibited HCC cell proliferation, migration and invasion through inactivation of HPIP and its downstream PI3K/AKT signaling pathway and suggested CSR1 as a potential therapy target for HCC treatment. 28975986 2017
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.040 AlteredExpression disease BEFREE Forced expression of CSR1 in prostate cancer cell lines DU145 and PC3 resulted in a two- to threefold decrease in colony formation and a 10-fold reduction in anchorage-independent growth. 16436673 2006
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.030 AlteredExpression disease BEFREE Forced expression of CSR1 in prostate cancer cell lines DU145 and PC3 resulted in a two- to threefold decrease in colony formation and a 10-fold reduction in anchorage-independent growth. 16436673 2006