Hypertensive disease
|
0.130 |
GeneticVariation
|
group |
GWASCAT |
Interethnic analyses of blood pressure loci in populations of East Asian and European descent.
|
30487518 |
2018 |
Hypertensive disease
|
0.130 |
Biomarker
|
group |
BEFREE |
Consistent with human findings, the lack of CST in CgA knockout (Chga-KO) mice eventuates in the development of hypertension and supplementation of CST to Chga-KO mice restores blood pressure, implicating CST as a key player in regulating hypertension.
|
28443506 |
2018 |
Breast Carcinoma
|
0.130 |
Biomarker
|
disease |
BEFREE |
Multiple breast cancer survival related genes were found in this gene set, including FOXR2, FOXD1, MTNR1B and SDC1.
|
30454048 |
2018 |
Hypertensive disease
|
0.130 |
Biomarker
|
group |
BEFREE |
Indeed, additional studies have revealed that the pro-inflammatory PST influences insulin sensitivity and glucose tolerance, whereas CST alleviates adiposity and hypertension.
|
28228748 |
2017 |
Breast Carcinoma
|
0.130 |
Biomarker
|
disease |
BEFREE |
Estrogen receptor percent positive staining is not independently related to breast cancer survival after adjustment for other survival-related factors.
|
28825224 |
2017 |
Breast Carcinoma
|
0.130 |
GeneticVariation
|
disease |
GWASCAT |
Association analysis identifies 65 new breast cancer risk loci.
|
29059683 |
2017 |
Hypertensive disease
|
0.130 |
GeneticVariation
|
group |
BEFREE |
Here, we report case-control studies in 2 geographically/ethnically distinct Indian populations (n≈4000) that showed association of the naturally-occurring human CST-Gly364Ser variant with increased risk for hypertension (age-adjusted odds ratios: 1.483; P=0.009 and 2.951; P=0.005).
|
27324226 |
2016 |
Cardiovascular Diseases
|
0.130 |
GeneticVariation
|
group |
BEFREE |
In conclusion, the CST Ser-364 allele may increase the risk for cardiovascular diseases in Japanese population.
|
26211667 |
2015 |
Hypertensive disease
|
0.130 |
GeneticVariation
|
group |
GWASCAT |
Genome-wide association study in Chinese identifies novel loci for blood pressure and hypertension.
|
25249183 |
2015 |
Breast Carcinoma
|
0.130 |
AlteredExpression
|
disease |
BEFREE |
A whole genome screening of the survival related gene expression patterns in breast cancer was studied.
|
26576432 |
2015 |
Varicosity
|
0.110 |
GeneticVariation
|
disease |
GWASCAT |
Varicose veins of lower extremities: Insights from the first large-scale genetic study.
|
30998689 |
2019 |
Varicosity
|
0.110 |
GeneticVariation
|
disease |
BEFREE |
Recent reports have suggested a reproducible association between the rs11121615 SNP, located within an intron of the castor zinc finger 1 (CASZ1) gene, and varicose veins.
|
31570750 |
2019 |
Varicosity
|
0.110 |
GeneticVariation
|
disease |
GWASCAT |
Clinical and Genetic Determinants of Varicose Veins.
|
30566020 |
2018 |
Glomerular Filtration Rate
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Sex-specific and pleiotropic effects underlying kidney function identified from GWAS meta-analysis.
|
31015462 |
2019 |
Glomerular Filtration Rate
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
A catalog of genetic loci associated with kidney function from analyses of a million individuals.
|
31152163 |
2019 |
White Blood Cell Count procedure
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
|
30595370 |
2019 |
Chronic Obstructive Airway Disease
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Genetic overlap of chronic obstructive pulmonary disease and cardiovascular disease-related traits: a large-scale genome-wide cross-trait analysis.
|
30940143 |
2019 |
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
In survival analysis, a low expression of CASZ1 was significantly correlated with unfavorable progression-free survival (PFS) (<i>p</i> < 0.001), overall survival (OS) (<i>p</i> < 0.001), and cancer-specific survival (CSS) (<i>p</i> < 0.001) and was an independent prognostic factor for PFS and CSS in multivariate analysis adjusted for tumor size, WHO/ISUP grade, T category, N category, and M category.
|
31481981 |
2019 |
Vital capacity
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
|
30595370 |
2019 |
Microalbuminuria
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria.
|
31511532 |
2019 |
Systolic Pressure
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Trans-ethnic association study of blood pressure determinants in over 750,000 individuals.
|
30578418 |
2019 |
Systolic Pressure
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
|
30595370 |
2019 |
Body mass index
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
|
30595370 |
2019 |
Body mass index
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry.
|
30239722 |
2019 |
RESTING HEART RATE
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Genetic overlap of chronic obstructive pulmonary disease and cardiovascular disease-related traits: a large-scale genome-wide cross-trait analysis.
|
30940143 |
2019 |