|
Hyperprolactinemia
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Prevalence of macroprolactinemia was 21.57% (22/102) in hyperprolactinemia (prolactin >100 ng/ml).
|
30269265 |
2019 |
|
Hyperprolactinemia
|
0.600 |
Biomarker
|
disease |
BEFREE |
Our findings support a possible role of prolactin in emerging psychosis and it could be speculated that stress, which can induce hyperprolactinemia, has a stronger effect on women than on men in emerging psychosis.
|
28214176 |
2017 |
|
Hyperprolactinemia
|
0.600 |
Biomarker
|
disease |
BEFREE |
The occurrence of big-big prolactin (PRL) as the major form of circulating immunoactive PRL has been described in ovulatory hyperprolactinemia.
|
3595901 |
1987 |
|
Hyperprolactinemia
|
0.600 |
Biomarker
|
disease |
BEFREE |
From a total of 174 people with serum prolactin measurements at study recruitment, 43% (n=74) had HPL, whilst 27% (n=21/78) and 27% (n=26/95) had HPL at 3 and 12months respectively.
|
28755878 |
2017 |
|
Hyperprolactinemia
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
The total cholesterol (baseline, 236.1 ± 47.6 mg/dl; endpoint [week 12], 209.9 ± 28.0 mg/dl; p = 0.005) and prolactin levels (baseline, 80.0 ± 85.2 ng/ml; endpoint [week 12], 63.2 ± 88.9 ng/ml; p = 0.003) were also significantly improved in patients with hypercholesterolemia or hyperprolactinemia.
|
31352709 |
2019 |
|
Hyperprolactinemia
|
0.600 |
Biomarker
|
disease |
BEFREE |
Key aspects include asymptomatic hyperprolactinemia monitoring and fertility considerations with PRL normalisation.
|
28889207 |
2017 |
|
Hyperprolactinemia
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
The study population consisted of 3 age-, weight-, and lipid-matched groups of young women: 19 women with untreated hyperprolactinemia (group A), 20 normoprolactinemic women receiving bromocriptine treatment (because of previous hyperprolactinemia) (group B), and 20 untreated women with prolactin levels within the reference range (group C).
|
30129670 |
2019 |
|
Hyperprolactinemia
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Some studies have reported that hyperprolactinemia is more common in RA and serum PRL levels are correlated with several disease parameters, although others could not confirm these findings.
|
28690611 |
2017 |
|
Hyperprolactinemia
|
0.600 |
Biomarker
|
disease |
CTD_human |
Development of anti-PRL (prolactin) autoantibodies by homologous PRL in rats: a model for macroprolactinemia.
|
17303669 |
2007 |
|
Hyperprolactinemia
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
High blood levels of PRL are associated with a poor prognosis in metastatic breast cancer whereas hyperprolactinemia after breast surgery may predict a better prognosis in women with operable breast cancer.
|
19181018 |
2009 |
|
Hyperprolactinemia
|
0.600 |
Biomarker
|
disease |
BEFREE |
The present study thus suggests that female patients with the A1 allele show greater prolactin response to bromperidol, who may have a high risk for adverse effects associated with neuroleptic-induced hyperprolactinemia.
|
11353448 |
2001 |
|
Hyperprolactinemia
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
The study population included 11 men with isolated macroprolactinemia, 14 subjects with monomeric hyperprolactinemia and 14 men with prolactin levels within the reference range.
|
31185509 |
2019 |
|
Hyperprolactinemia
|
0.600 |
Biomarker
|
disease |
LHGDN |
Pituitary production of prolactin and prolactin-suppressing drugs.
|
11721691 |
2001 |
|
Hyperprolactinemia
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
The study enrolled 30 young women with mild hyperprolactinemia (serum prolactin levels in the range between 25 and 50ng/mL), 15 of whom were later treated with bromocriptine (5-10mg daily), as well as 14 age- and weight-matched healthy women.
|
29475005 |
2018 |
|
Hyperprolactinemia
|
0.600 |
Biomarker
|
disease |
BEFREE |
A total of 95% of the 20 patients with hyperprolactinemia had progressive disease (PD), according to CT results, whereas only 2 patients (33%) out of 6 with stable PRL levels had PD (p = 0.004).
|
28407622 |
2017 |
|
Hyperprolactinemia
|
0.600 |
Biomarker
|
disease |
BEFREE |
Univariate survival analysis showed that patients with pretherapeutic hyperprolactinemia had a significantly shorter overall survival than patients with pretherapeutic PRL <15.0 ng/mL serum (p =.0009).
|
10748449 |
2000 |
|
Hyperprolactinemia
|
0.600 |
Biomarker
|
disease |
BEFREE |
This review aims to summarize current knowledge about PRL and its receptor, role in reproductive axis and presents information of hyperprolactinemia in reproductive medicine.
|
17307904 |
2007 |
|
Hyperprolactinemia
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Prolactin takes calcium from the skeletal system following increased Prlr gene expression in the vertebrae to maintain calcium homeostasis, which increases the harmful effect on bone metabolism compared to that of physiological hyperprolactinaemia.
|
30143940 |
2018 |
|
Hyperprolactinemia
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Abnormalities in thyroid function and hyperprolactinemia are well-known causes of infertility, but whether thyrotropin (TSH) and prolactin levels within the normal range are associated with UI is unknown.
|
29272395 |
2018 |
|
Hyperprolactinemia
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Big big PRL or macroprolactin is a PRL variant with reduced bioactivity towards its homologous receptor, and this altered bioactivity may contribute to the lower disease activity and absence of symptoms related to HPRL in SLE patients.
|
17516622 |
2007 |
|
Hyperprolactinemia
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Sex and age were significantly associated with PRL levels in patients treated with LAI antipsychotics, with younger women presenting higher rates of HPRL than men.
|
30848967 |
2019 |
|
Hyperprolactinemia
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Hyperprolactinemia was found to be present in Case 2, whereas Case 1 (a 49-year-old woman) had "normal" serum prolactin levels for premenopausal and prolactin levels slightly above the maximum levels for postmenopausal women.
|
31417404 |
2019 |
|
Hyperprolactinemia
|
0.600 |
Biomarker
|
disease |
BEFREE |
Although there were significant differences in the prevalence of hyperprolactinemia and metabolic syndrome according to the antipsychotic received, multivariant regression analysis did not show a correlation between sexual dysfunction and prolactin, sexual hormones, type of antipsychotic received, psychotic psychopathology or metabolic syndrome.
|
30552811 |
2018 |
|
Hyperprolactinemia
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Future prospects for hyperprolactinemia may require diagnostic criteria using free prolactin levels and so MPRL fraction measurement is important for the diagnosis and treatment of patients with obstetric and gynecological symptoms.
|
29162783 |
2018 |
|
Hyperprolactinemia
|
0.600 |
Biomarker
|
disease |
BEFREE |
It was also demonstrated that prolactin played an important role in body weight regulation and hyperprolactinemia can promote appetite and accelerate fat deposition.
|
30124145 |
2018 |