|
Hashimoto Disease
|
0.100 |
Biomarker
|
disease |
BEFREE |
<i>Results.</i> The percentage of CRTH2+ lymphocytes was higher in nodules with HT in comparison with controls, both in FNAB samples (13.95 versus 6.7%, <i>p</i> = 0.008) and in peripheral blood (6.7 versus 5.13%, <i>p</i> = 0.047), and positively correlated with serum antibodies to thyroid peroxidase (<i>r</i> = 0.243; <i>p</i> = 0.026) and negatively correlated with thyroid volume (<i>r</i> = -0.346; <i>p</i> = 0.008).
|
27872865 |
2016 |
|
Hashimoto Disease
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Autoimmune thyroiditis with raised levels of thyroperoxidase antibodies (TPO-Abs) is related to bipolar disorder and may be such an endophenotype.
|
17141745 |
2007 |
|
Hashimoto Disease
|
0.100 |
Biomarker
|
disease |
BEFREE |
Thyroid Peroxidase as an Autoantigen in Hashimoto's Disease: Structure, Function, and Antigenicity.
|
30360003 |
2018 |
|
Hashimoto Disease
|
0.100 |
Biomarker
|
disease |
BEFREE |
A diagnosis of autoimmune thyroiditis (AT) in thyrotoxic phase was made on the basis of clinical presentation and presence of anti-TPO antibodies and reduced uptake in thyroid (technetium) scintigraphy.
|
30128632 |
2019 |
|
Hashimoto Disease
|
0.100 |
Biomarker
|
disease |
BEFREE |
Antibodies to thyroid peroxidase (TPO), the enzyme that catalyses thyroid-hormone production and antibodies to the receptor for the thyroid-stimulating hormone, are characteristic of HT and GD, respectively.
|
30208979 |
2019 |
|
Hashimoto Disease
|
0.100 |
Biomarker
|
disease |
BEFREE |
Autoimmunity to TPO is characterised by autoantibodies and T cell reactivity in Hashimoto's disease and Graves' disease.
|
30742860 |
2019 |
|
Hashimoto Disease
|
0.100 |
Biomarker
|
disease |
BEFREE |
Conclusions Fluctuating thyroid function tests in addition to thyroid peroxidase antibody (TPO Ab) positivity complicated the diagnosis of RTH, initially diagnosed as Hashimoto's thyroiditis.
|
30681972 |
2019 |
|
Hashimoto Disease
|
0.100 |
AlteredExpression
|
disease |
LHGDN |
Effects of 12 months treatment with L-selenomethionine on serum anti-TPO Levels in Patients with Hashimoto's thyroiditis.
|
17696828 |
2007 |
|
Hashimoto Disease
|
0.100 |
Biomarker
|
disease |
BEFREE |
Green coffee, green tea, cumin, and mustard contain potentially bioaccessible TPO activators that also act as effective LOX inhibitors, which indicate their potentially health-promoting effects for people suffering from Hashimoto's disease.
|
31671724 |
2019 |
|
Hashimoto Disease
|
0.100 |
Biomarker
|
disease |
BEFREE |
Hyperthyroidism in Graves' disease is caused by thyroid-stimulating autoantibodies to the TSH receptor (TSHR), whereas hypothyroidism in Hashimoto's thyroiditis is associated with thyroid peroxidase and thyroglobulin autoantibodies.
|
17823263 |
2007 |
|
Hashimoto Disease
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
In conclusion, TPO rs2071400 and rs2071403 polymorphisms were associated with the development of HD and GD, but not with the prognosis.
|
28845025 |
2017 |
|
Hashimoto Disease
|
0.100 |
Biomarker
|
disease |
BEFREE |
In FNAC studies, the association between HT and PTC is based on the comparison of anti-thyroid autoantibodies (ATA) (anti-thyroperoxidase [TPOAb] and anti-thyroglobulin [TgAb]), thyroid function (TSH), and cytology with histology of thyroid nodules and lymphocytic thyroid infiltration (LTI) of operated thyroid glands.
|
28868258 |
2017 |
|
Hashimoto Disease
|
0.100 |
Biomarker
|
disease |
BEFREE |
In our study, prevalence of TPO-Ab positivity is more frequent in subjects with <i>H. pylori</i> infection.Our findings suggest <i>H. pylori</i> infection may play a role in the development of autoimmune thyroiditis.
|
28092700 |
2017 |
|
Hashimoto Disease
|
0.100 |
Biomarker
|
disease |
BEFREE |
In those with HT, MMP-3 correlated negatively with FT3 (rho=-0.545, P=0.048) and positively with TPO-Ab and HI (rho=0.735, P=0.02; rho=0.769, P=0.01, respectively).
|
29442475 |
2018 |
|
Hashimoto Disease
|
0.100 |
Biomarker
|
disease |
BEFREE |
Independent risk factors for events were baseline findings for TSH and TPO antibodies in a level-dependent relationship (for TSH the risk already starts to increase at values >2.0 mIU/L) and family background (with the greatest risk attached to subjects having 2 relatives with Hashimoto disease).
|
18695079 |
2008 |
|
Hashimoto Disease
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Individuals with positive thyroid peroxidase antibodies (TPOAbs) have an increased risk of autoimmune hypothyroidism (Hashimoto's thyroiditis), as well as autoimmune hyperthyroidism (Graves' disease).
|
24586183 |
2014 |
|
Hashimoto Disease
|
0.100 |
Biomarker
|
disease |
BEFREE |
Instead, our finding that low dietary Se potentiates the development of autoantibodies to Tg and TPO in females is consistent with reports in humans of an increased prevalence of autoimmune thyroiditis in low-Se regions.
|
28938453 |
2017 |
|
Hashimoto Disease
|
0.100 |
Biomarker
|
disease |
BEFREE |
It has been reported that serum of patients with RTH lacks autoantibodies against thyroglobulin (Tg) and thyroid peroxidase (TPO), except in rare cases where there is co-occurrence of coincidental autoimmune thyroiditis.
|
16723809 |
2006 |
|
Hashimoto Disease
|
0.100 |
Biomarker
|
disease |
BEFREE |
It is generally believed that the detection of thyroid peroxidase antibodies (TPOAb) is superior to that of thyroglobulin antibodies (TgAb) for the diagnosis of Hashimoto's thyroiditis.
|
28768936 |
2017 |
|
Hashimoto Disease
|
0.100 |
Biomarker
|
disease |
BEFREE |
Modulation of T cell function by alpha-fetoprotein: An in vivo study on porcine thyroid peroxidase-induced experimental autoimmune thyroiditis in transgenic mice producing human alpha-fetoprotein.
|
10213924 |
1999 |
|
Hashimoto Disease
|
0.100 |
Biomarker
|
disease |
BEFREE |
Monozygotic twin pairs discordant for Hashimoto's thyroiditis share a high proportion of thyroid peroxidase autoantibodies to the immunodominant region A. Further evidence for genetic transmission of epitopic "fingerprints".
|
20883148 |
2011 |
|
Hashimoto Disease
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Most importantly, only Tfh17 cell percentages were positively correlated with anti-thyroglobulin and anti-thyroid peroxidase antibody levels and were negatively correlated serum free T3 and free T4 levels in HT patients.
|
30345813 |
2018 |
|
Hashimoto Disease
|
0.100 |
Biomarker
|
disease |
BEFREE |
Only data from patients with laboratory-confirmed HT (anti-thyroid peroxidase [anti-TPO] antibodies; thyroglobulin antibodies; serum thyroid-stimulating hormone; and free T3) were eligible for inclusion.
|
28217937 |
2017 |
|
Hashimoto Disease
|
0.100 |
Biomarker
|
disease |
BEFREE |
Our key and novel finding is the existence of significant positive correlation between TgAb levels and the number of symptoms (r = 0.25, p = 0.0001) in HT patients without LT4 therapy that remained significant after adjustment for TPOAb, T3, TSH levels and thyroid volume (β = 0.66, SE = 0.3, p = 0.0299).
|
30332318 |
2019 |
|
Hashimoto Disease
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Results showed that DHA can visibly reduce antithyroglobulin antibody and thyroid peroxidase antibody levels and regulate T helper cells (Th) 1/Th2 imbalance of experimental AIT mice.
|
29383139 |
2017 |