NRAS, NRAS proto-oncogene, GTPase, 4893

N. diseases: 611; N. variants: 17
Source: ALL
Variant DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Disease Disease Class Score vda EI vda N. PMIDs First Ref. Last Ref.
dbSNP: rs7549358
rs7549358 		1 114709988 intron variant G/A;C;T snv
CUI: C1305855
Disease: Body mass index
Body mass index 		0.700 1.000 1 2019 2019
dbSNP: rs1057519695
rs1057519695 		0.641 0.520 1 114713907 missense variant TT/CA;CC mnv
CUI: C0025202
Disease: melanoma
melanoma 		Neoplasms 0.800 1.000 30 1989 2019
dbSNP: rs121913255
rs121913255 		0.667 0.400 1 114713907 missense variant T/A;G snv
CUI: C0025202
Disease: melanoma
melanoma 		Neoplasms 0.700 1.000 13 1989 2014
dbSNP: rs1057519695
rs1057519695 		0.641 0.520 1 114713907 missense variant TT/CA;CC mnv
CUI: C0027651
Disease: Neoplasms
Neoplasms 		Neoplasms 0.100 1.000 11 2011 2019
dbSNP: rs1057519695
rs1057519695 		0.641 0.520 1 114713907 missense variant TT/CA;CC mnv
CUI: C0278883
Disease: Metastatic melanoma
Metastatic melanoma 		Neoplasms 0.030 1.000 3 2015 2016
dbSNP: rs121913255
rs121913255 		0.667 0.400 1 114713907 missense variant T/A;G snv
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		Neoplasms; Respiratory Tract Diseases 0.700 1.000 3 2002 2013
dbSNP: rs1057519695
rs1057519695 		0.641 0.520 1 114713907 missense variant TT/CA;CC mnv
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm 		Neoplasms; Endocrine System Diseases 0.020 1.000 2 2016 2017
dbSNP: rs1057519695
rs1057519695 		0.641 0.520 1 114713907 missense variant TT/CA;CC mnv
CUI: C1318558
Disease: Congenital melanocytic nevus
Congenital melanocytic nevus 		Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Skin and Connective Tissue Diseases 0.020 1.000 2 2016 2017
dbSNP: rs1057519695
rs1057519695 		0.641 0.520 1 114713907 missense variant TT/CA;CC mnv
CUI: C0206682
Disease: Follicular thyroid carcinoma
Follicular thyroid carcinoma 		Neoplasms 0.020 1.000 2 2016 2018
dbSNP: rs121913255
rs121913255 		0.667 0.400 1 114713907 missense variant T/A;G snv
CUI: C0023467
Disease: Leukemia, Myelocytic, Acute
Leukemia, Myelocytic, Acute 		Neoplasms 0.700 1.000 2 2009 2016
dbSNP: rs1057519695
rs1057519695 		0.641 0.520 1 114713907 missense variant TT/CA;CC mnv
CUI: C1868683
Disease: B-CELL MALIGNANCY, LOW-GRADE
B-CELL MALIGNANCY, LOW-GRADE 		0.010 1.000 1 1997 1997
dbSNP: rs1057519695
rs1057519695 		0.641 0.520 1 114713907 missense variant TT/CA;CC mnv
CUI: C0023449
Disease: Acute lymphocytic leukemia
Acute lymphocytic leukemia 		Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases 0.010 1.000 1 2016 2016
dbSNP: rs1057519695
rs1057519695 		0.641 0.520 1 114713907 missense variant TT/CA;CC mnv
CUI: C3536983
Disease: Familial Hypophosphatemic Rickets
Familial Hypophosphatemic Rickets 		Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Musculoskeletal Diseases; Male Urogenital Diseases 0.010 1.000 1 2017 2017
dbSNP: rs1057519695
rs1057519695 		0.641 0.520 1 114713907 missense variant TT/CA;CC mnv
CUI: C0238463
Disease: Papillary thyroid carcinoma
Papillary thyroid carcinoma 		Neoplasms; Endocrine System Diseases 0.010 1.000 1 2019 2019
dbSNP: rs1057519695
rs1057519695 		0.641 0.520 1 114713907 missense variant TT/CA;CC mnv
CUI: C0007133
Disease: Carcinoma, Papillary
Carcinoma, Papillary 		Neoplasms 0.010 1.000 1 2018 2018
dbSNP: rs1057519695
rs1057519695 		0.641 0.520 1 114713907 missense variant TT/CA;CC mnv
CUI: C0030354
Disease: Papilloma
Papilloma 		Neoplasms 0.010 1.000 1 2014 2014
dbSNP: rs1057519695
rs1057519695 		0.641 0.520 1 114713907 missense variant TT/CA;CC mnv
CUI: C0153690
Disease: Secondary malignant neoplasm of bone
Secondary malignant neoplasm of bone 		Pathological Conditions, Signs and Symptoms; Neoplasms; Musculoskeletal Diseases 0.010 1.000 1 2018 2018
dbSNP: rs1057519695
rs1057519695 		0.641 0.520 1 114713907 missense variant TT/CA;CC mnv
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		Neoplasms 0.010 1.000 1 2019 2019
dbSNP: rs1057519695
rs1057519695 		0.641 0.520 1 114713907 missense variant TT/CA;CC mnv
CUI: C1704375
Disease: Hypophosphatemic Rickets
Hypophosphatemic Rickets 		Nutritional and Metabolic Diseases; Musculoskeletal Diseases 0.010 1.000 1 2017 2017
dbSNP: rs1057519695
rs1057519695 		0.641 0.520 1 114713907 missense variant TT/CA;CC mnv
CUI: C0549473
Disease: Thyroid carcinoma
Thyroid carcinoma 		Neoplasms; Endocrine System Diseases 0.010 1.000 1 2016 2016
dbSNP: rs1057519695
rs1057519695 		0.641 0.520 1 114713907 missense variant TT/CA;CC mnv
CUI: C1961102
Disease: Precursor Cell Lymphoblastic Leukemia Lymphoma
Precursor Cell Lymphoblastic Leukemia Lymphoma 		Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases 0.010 1.000 1 2016 2016
dbSNP: rs1057519695
rs1057519695 		0.641 0.520 1 114713907 missense variant TT/CA;CC mnv
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm 		Neoplasms 0.010 1.000 1 2019 2019
dbSNP: rs1057519695
rs1057519695 		0.641 0.520 1 114713907 missense variant TT/CA;CC mnv
CUI: C0079744
Disease: Diffuse Large B-Cell Lymphoma
Diffuse Large B-Cell Lymphoma 		Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases 0.010 1.000 1 1997 1997
dbSNP: rs1057519695
rs1057519695 		0.641 0.520 1 114713907 missense variant TT/CA;CC mnv
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis 		Pathological Conditions, Signs and Symptoms; Neoplasms 0.010 1.000 1 2017 2017
dbSNP: rs1057519695
rs1057519695 		0.641 0.520 1 114713907 missense variant TT/CA;CC mnv
CUI: C0205748
Disease: Dysplastic Nevus
Dysplastic Nevus 		Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms 0.010 1.000 1 2019 2019