NRAS, NRAS proto-oncogene, GTPase, 4893

N. diseases: 611; N. variants: 17
Source: ALL
Variant DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Disease Disease Class Score vda EI vda N. PMIDs First Ref. Last Ref.
dbSNP: rs1057519695
rs1057519695 		0.641 0.520 1 114713907 missense variant TT/CA;CC mnv
CUI: C1868683
Disease: B-CELL MALIGNANCY, LOW-GRADE
B-CELL MALIGNANCY, LOW-GRADE 		0.010 1.000 1 1997 1997
dbSNP: rs1057519695
rs1057519695 		0.641 0.520 1 114713907 missense variant TT/CA;CC mnv
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion 		0.010 1.000 1 2015 2015
dbSNP: rs1057519695
rs1057519695 		0.641 0.520 1 114713907 missense variant TT/CA;CC mnv
CUI: C1337013
Disease: Differentiated Thyroid Gland Carcinoma
Differentiated Thyroid Gland Carcinoma 		0.010 1.000 1 2014 2014
dbSNP: rs1057519834
rs1057519834 		0.658 0.480 1 114713908 missense variant TG/CT mnv
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion 		0.010 1.000 1 2015 2015
dbSNP: rs1057519834
rs1057519834 		0.658 0.480 1 114713908 missense variant TG/CT mnv
CUI: C1337013
Disease: Differentiated Thyroid Gland Carcinoma
Differentiated Thyroid Gland Carcinoma 		0.010 1.000 1 2014 2014
dbSNP: rs1057519834
rs1057519834 		0.658 0.480 1 114713908 missense variant TG/CT mnv
CUI: C1868683
Disease: B-CELL MALIGNANCY, LOW-GRADE
B-CELL MALIGNANCY, LOW-GRADE 		0.010 1.000 1 1997 1997
dbSNP: rs11554290
rs11554290 		0.583 0.600 1 114713908 missense variant T/A;C;G snv
CUI: C1337013
Disease: Differentiated Thyroid Gland Carcinoma
Differentiated Thyroid Gland Carcinoma 		0.010 1.000 1 2014 2014
dbSNP: rs11554290
rs11554290 		0.583 0.600 1 114713908 missense variant T/A;C;G snv
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion 		0.010 1.000 1 2015 2015
dbSNP: rs11554290
rs11554290 		0.583 0.600 1 114713908 missense variant T/A;C;G snv
CUI: C1868683
Disease: B-CELL MALIGNANCY, LOW-GRADE
B-CELL MALIGNANCY, LOW-GRADE 		0.010 1.000 1 1997 1997
dbSNP: rs121434596
rs121434596 		0.677 0.440 1 114716123 missense variant C/A;G;T snv 4.0E-06; 4.0E-06
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.010 1.000 1 2016 2016
dbSNP: rs121913237
rs121913237 		0.611 0.560 1 114716126 missense variant C/A;G;T snv 8.0E-06
CUI: C1868683
Disease: B-CELL MALIGNANCY, LOW-GRADE
B-CELL MALIGNANCY, LOW-GRADE 		0.010 1.000 1 1997 1997
dbSNP: rs121913237
rs121913237 		0.611 0.560 1 114716126 missense variant C/A;G;T snv 8.0E-06
CUI: C4049272
Disease: Tumour budding
Tumour budding 		0.010 1.000 1 2017 2017
dbSNP: rs121913237
rs121913237 		0.611 0.560 1 114716126 missense variant C/A;G;T snv 8.0E-06
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion 		0.010 1.000 1 2017 2017
dbSNP: rs121913237
rs121913237 		0.611 0.560 1 114716126 missense variant C/A;G;T snv 8.0E-06
CUI: C0349636
Disease: Pre B-cell acute lymphoblastic leukemia
Pre B-cell acute lymphoblastic leukemia 		0.010 1.000 1 2014 2014
dbSNP: rs121913237
rs121913237 		0.611 0.560 1 114716126 missense variant C/A;G;T snv 8.0E-06
CUI: C1378511
Disease: Undifferentiated leukemia
Undifferentiated leukemia 		0.010 1.000 1 2014 2014
dbSNP: rs121913237
rs121913237 		0.611 0.560 1 114716126 missense variant C/A;G;T snv 8.0E-06
CUI: C0280141
Disease: Acute Undifferentiated Leukemia
Acute Undifferentiated Leukemia 		0.010 1.000 1 2014 2014
dbSNP: rs121913250
rs121913250 		0.683 0.440 1 114716127 missense variant C/A;G;T snv
CUI: C1868683
Disease: B-CELL MALIGNANCY, LOW-GRADE
B-CELL MALIGNANCY, LOW-GRADE 		0.010 1.000 1 1997 1997
dbSNP: rs121913254
rs121913254 		0.658 0.440 1 114713909 stop gained G/A;C;T snv
CUI: C1306726
Disease: Congenital naevus
Congenital naevus 		0.010 1.000 1 2016 2016
dbSNP: rs121913254
rs121913254 		0.658 0.440 1 114713909 stop gained G/A;C;T snv
CUI: C1334386
Disease: Meningeal melanoma
Meningeal melanoma 		0.010 1.000 1 2016 2016
dbSNP: rs121913254
rs121913254 		0.658 0.440 1 114713909 stop gained G/A;C;T snv
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.010 1.000 1 2013 2013
dbSNP: rs121913255
rs121913255 		0.667 0.400 1 114713907 missense variant T/A;G snv
CUI: C4520732
Disease: Stage IV Cutaneous Melanoma AJCC v6 and v7
Stage IV Cutaneous Melanoma AJCC v6 and v7 		0.010 1.000 1 2015 2015
dbSNP: rs7549358
rs7549358 		1 114709988 intron variant G/A;C;T snv
CUI: C1305855
Disease: Body mass index
Body mass index 		0.700 1.000 1 2019 2019
dbSNP: rs11554290
rs11554290 		0.583 0.600 1 114713908 missense variant T/A;C;G snv
CUI: C4225426
Disease: THYROID CANCER, NONMEDULLARY, 2
THYROID CANCER, NONMEDULLARY, 2 		0.800 0
dbSNP: rs1057519695
rs1057519695 		0.641 0.520 1 114713907 missense variant TT/CA;CC mnv
CUI: C0008626
Disease: Congenital chromosomal disease
Congenital chromosomal disease 		Congenital, Hereditary, and Neonatal Diseases and Abnormalities 0.010 1.000 1 2018 2018
dbSNP: rs1057519834
rs1057519834 		0.658 0.480 1 114713908 missense variant TG/CT mnv
CUI: C0008626
Disease: Congenital chromosomal disease
Congenital chromosomal disease 		Congenital, Hereditary, and Neonatal Diseases and Abnormalities 0.010 1.000 1 2018 2018