OPRM1, opioid receptor mu 1, 4988

N. diseases: 370; N. variants: 42
Source: ALL
Variant DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Disease Disease Class Score vda EI vda N. PMIDs First Ref. Last Ref.
dbSNP: rs1799971
rs1799971 		0.559 0.600 6 154039662 missense variant A/G snv 0.19 0.12
CUI: C0184567
Disease: Acute onset pain
Acute onset pain 		Pathological Conditions, Signs and Symptoms 0.010 1.000 1 2008 2008
dbSNP: rs17174794
rs17174794 		1.000 6 154089975 missense variant C/G;T snv 4.1E-03
CUI: C0858353
Disease: Addicted to heroin
Addicted to heroin 		0.010 1.000 1 2013 2013
dbSNP: rs17174801
rs17174801 		1.000 6 154089989 missense variant A/G snv 6.9E-04 2.8E-03
CUI: C0858353
Disease: Addicted to heroin
Addicted to heroin 		0.010 1.000 1 2013 2013
dbSNP: rs1799971
rs1799971 		0.559 0.600 6 154039662 missense variant A/G snv 0.19 0.12
CUI: C0858353
Disease: Addicted to heroin
Addicted to heroin 		0.010 1.000 1 2013 2013
dbSNP: rs62638690
rs62638690 		0.925 0.080 6 154090110 missense variant G/T snv 5.6E-03 5.6E-03
CUI: C0858353
Disease: Addicted to heroin
Addicted to heroin 		0.010 1.000 1 2013 2013
dbSNP: rs1799971
rs1799971 		0.559 0.600 6 154039662 missense variant A/G snv 0.19 0.12
CUI: C0085281
Disease: Addictive Behavior
Addictive Behavior 		Behavior and Behavior Mechanisms 0.090 1.000 9 2004 2019
dbSNP: rs769540300
rs769540300 		0.851 0.200 6 154091047 missense variant G/A snv 1.2E-05
CUI: C0085281
Disease: Addictive Behavior
Addictive Behavior 		Behavior and Behavior Mechanisms 0.010 1.000 1 2004 2004
dbSNP: rs1799971
rs1799971 		0.559 0.600 6 154039662 missense variant A/G snv 0.19 0.12
CUI: C0563625
Disease: Agnosia for Pain
Agnosia for Pain 		Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms 0.100 0.944 18 2006 2019
dbSNP: rs769540300
rs769540300 		0.851 0.200 6 154091047 missense variant G/A snv 1.2E-05
CUI: C0563625
Disease: Agnosia for Pain
Agnosia for Pain 		Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms 0.020 1.000 2 2008 2018
dbSNP: rs1187761291
rs1187761291 		1.000 0.120 6 154039569 missense variant A/G snv 4.1E-06
CUI: C0563625
Disease: Agnosia for Pain
Agnosia for Pain 		Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms 0.010 < 0.001 1 2010 2010
dbSNP: rs200811844
rs200811844 		1.000 0.120 6 154091110 missense variant T/C snv 1.8E-04 7.8E-04
CUI: C0563625
Disease: Agnosia for Pain
Agnosia for Pain 		Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms 0.010 1.000 1 2016 2016
dbSNP: rs1799971
rs1799971 		0.559 0.600 6 154039662 missense variant A/G snv 0.19 0.12
CUI: C0085762
Disease: Alcohol abuse
Alcohol abuse 		Chemically-Induced Disorders; Mental Disorders 0.010 1.000 1 2014 2014
dbSNP: rs1799971
rs1799971 		0.559 0.600 6 154039662 missense variant A/G snv 0.19 0.12
CUI: C0237123
Disease: Alcohol or Other Drugs use
Alcohol or Other Drugs use 		0.010 1.000 1 2017 2017
dbSNP: rs3778150
rs3778150 		0.925 0.080 6 154062523 intron variant T/C snv 0.17
CUI: C0237123
Disease: Alcohol or Other Drugs use
Alcohol or Other Drugs use 		0.010 1.000 1 2017 2017
dbSNP: rs199953844
rs199953844 		6 154039650 missense variant C/A;T snv 4.0E-06; 1.2E-04
CUI: C0549393
Disease: Alcohol problem
Alcohol problem 		0.010 1.000 1 2014 2014
dbSNP: rs1799971
rs1799971 		0.559 0.600 6 154039662 missense variant A/G snv 0.19 0.12
CUI: C0001956
Disease: Alcohol Use Disorder
Alcohol Use Disorder 		Chemically-Induced Disorders; Mental Disorders 0.070 0.857 7 2010 2018
dbSNP: rs1799971
rs1799971 		0.559 0.600 6 154039662 missense variant A/G snv 0.19 0.12
CUI: C0001957
Disease: Alcohol Withdrawal Delirium
Alcohol Withdrawal Delirium 		Nervous System Diseases; Chemically-Induced Disorders; Mental Disorders 0.010 1.000 1 2019 2019
dbSNP: rs1799971
rs1799971 		0.559 0.600 6 154039662 missense variant A/G snv 0.19 0.12
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic 		Chemically-Induced Disorders; Mental Disorders 0.100 0.893 28 1998 2019
dbSNP: rs769540300
rs769540300 		0.851 0.200 6 154091047 missense variant G/A snv 1.2E-05
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic 		Chemically-Induced Disorders; Mental Disorders 0.010 1.000 1 2004 2004
dbSNP: rs1799971
rs1799971 		0.559 0.600 6 154039662 missense variant A/G snv 0.19 0.12
CUI: C0233702
Disease: Algophobia
Algophobia 		Mental Disorders 0.010 1.000 1 2018 2018
dbSNP: rs1799971
rs1799971 		0.559 0.600 6 154039662 missense variant A/G snv 0.19 0.12
CUI: C0003467
Disease: Anxiety
Anxiety 		Behavior and Behavior Mechanisms 0.030 0.667 3 2002 2018
dbSNP: rs769540300
rs769540300 		0.851 0.200 6 154091047 missense variant G/A snv 1.2E-05
CUI: C0003467
Disease: Anxiety
Anxiety 		Behavior and Behavior Mechanisms 0.010 1.000 1 2004 2004
dbSNP: rs1799971
rs1799971 		0.559 0.600 6 154039662 missense variant A/G snv 0.19 0.12
CUI: C0003469
Disease: Anxiety Disorders
Anxiety Disorders 		Mental Disorders 0.030 0.667 3 2002 2018
dbSNP: rs769540300
rs769540300 		0.851 0.200 6 154091047 missense variant G/A snv 1.2E-05
CUI: C0003469
Disease: Anxiety Disorders
Anxiety Disorders 		Mental Disorders 0.010 1.000 1 2004 2004
dbSNP: rs1799971
rs1799971 		0.559 0.600 6 154039662 missense variant A/G snv 0.19 0.12
CUI: C0085632
Disease: Apathy
Apathy 		Behavior and Behavior Mechanisms 0.010 1.000 1 2013 2013