OPRM1, opioid receptor mu 1, 4988

N. diseases: 370; N. variants: 42
Source: ALL
Variant DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Disease Disease Class Score vda EI vda N. PMIDs First Ref. Last Ref.
dbSNP: rs2236256
rs2236256 		0.925 0.120 6 154157305 3 prime UTR variant C/A snv 0.52
CUI: C0023434
Disease: Chronic Lymphocytic Leukemia
Chronic Lymphocytic Leukemia 		Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases 0.800 1.000 1 2014 2014
dbSNP: rs2236256
rs2236256 		0.925 0.120 6 154157305 3 prime UTR variant C/A snv 0.52
CUI: C0855095
Disease: Small Lymphocytic Lymphoma
Small Lymphocytic Lymphoma 		Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases 0.700 1.000 1 2014 2014
dbSNP: rs4869818
rs4869818 		0.925 0.120 6 154150090 intron variant G/A snv 0.54
CUI: C0023434
Disease: Chronic Lymphocytic Leukemia
Chronic Lymphocytic Leukemia 		Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases 0.700 1.000 1 2017 2017
dbSNP: rs4869818
rs4869818 		0.925 0.120 6 154150090 intron variant G/A snv 0.54
CUI: C0855095
Disease: Small Lymphocytic Lymphoma
Small Lymphocytic Lymphoma 		Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases 0.700 1.000 1 2017 2017
dbSNP: rs598682
rs598682 		6 154097624 intron variant A/G;T snv
CUI: C0428883
Disease: Diastolic blood pressure
Diastolic blood pressure 		0.700 1.000 1 2018 2018
dbSNP: rs9478496
rs9478496 		6 154012048 intron variant T/C;G snv
CUI: C1305855
Disease: Body mass index
Body mass index 		0.700 1.000 1 2019 2019
dbSNP: rs1799971
rs1799971 		0.559 0.600 6 154039662 missense variant A/G snv 0.19 0.12
CUI: C0030193
Disease: Pain
Pain 		Pathological Conditions, Signs and Symptoms 0.100 0.979 47 2004 2019
dbSNP: rs1799971
rs1799971 		0.559 0.600 6 154039662 missense variant A/G snv 0.19 0.12
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic 		Chemically-Induced Disorders; Mental Disorders 0.100 0.893 28 1998 2019
dbSNP: rs1799971
rs1799971 		0.559 0.600 6 154039662 missense variant A/G snv 0.19 0.12
CUI: C0563625
Disease: Agnosia for Pain
Agnosia for Pain 		Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms 0.100 0.944 18 2006 2019
dbSNP: rs1799971
rs1799971 		0.559 0.600 6 154039662 missense variant A/G snv 0.19 0.12
CUI: C0524662
Disease: Opiate Addiction
Opiate Addiction 		Chemically-Induced Disorders; Mental Disorders 0.100 0.900 10 2001 2020
dbSNP: rs1799971
rs1799971 		0.559 0.600 6 154039662 missense variant A/G snv 0.19 0.12
CUI: C0085281
Disease: Addictive Behavior
Addictive Behavior 		Behavior and Behavior Mechanisms 0.090 1.000 9 2004 2019
dbSNP: rs1799971
rs1799971 		0.559 0.600 6 154039662 missense variant A/G snv 0.19 0.12
CUI: C0001956
Disease: Alcohol Use Disorder
Alcohol Use Disorder 		Chemically-Induced Disorders; Mental Disorders 0.070 0.857 7 2010 2018
dbSNP: rs1799971
rs1799971 		0.559 0.600 6 154039662 missense variant A/G snv 0.19 0.12
CUI: C0019337
Disease: Heroin Dependence
Heroin Dependence 		Chemically-Induced Disorders; Mental Disorders 0.070 0.857 7 2001 2017
dbSNP: rs1799971
rs1799971 		0.559 0.600 6 154039662 missense variant A/G snv 0.19 0.12
CUI: C0030201
Disease: Pain, Postoperative
Pain, Postoperative 		Pathological Conditions, Signs and Symptoms 0.070 0.857 7 2006 2019
dbSNP: rs1799971
rs1799971 		0.559 0.600 6 154039662 missense variant A/G snv 0.19 0.12
CUI: C1510472
Disease: Drug Dependence
Drug Dependence 		Chemically-Induced Disorders; Mental Disorders 0.060 1.000 6 2005 2018
dbSNP: rs1799971
rs1799971 		0.559 0.600 6 154039662 missense variant A/G snv 0.19 0.12
CUI: C0038580
Disease: Substance Dependence
Substance Dependence 		Chemically-Induced Disorders; Mental Disorders 0.060 0.833 6 2001 2016
dbSNP: rs1799971
rs1799971 		0.559 0.600 6 154039662 missense variant A/G snv 0.19 0.12
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		Mental Disorders 0.040 0.750 4 2010 2019
dbSNP: rs1799971
rs1799971 		0.559 0.600 6 154039662 missense variant A/G snv 0.19 0.12
CUI: C0011570
Disease: Mental Depression
Mental Depression 		Behavior and Behavior Mechanisms 0.030 0.667 3 2002 2015
dbSNP: rs1799971
rs1799971 		0.559 0.600 6 154039662 missense variant A/G snv 0.19 0.12
CUI: C0028043
Disease: Nicotine Dependence
Nicotine Dependence 		Chemically-Induced Disorders; Mental Disorders 0.030 0.667 3 2011 2017
dbSNP: rs1799971
rs1799971 		0.559 0.600 6 154039662 missense variant A/G snv 0.19 0.12
CUI: C0596240
Disease: Cancer Pain
Cancer Pain 		Pathological Conditions, Signs and Symptoms 0.030 1.000 3 2013 2019
dbSNP: rs1799971
rs1799971 		0.559 0.600 6 154039662 missense variant A/G snv 0.19 0.12
CUI: C0344315
Disease: Depressed mood
Depressed mood 		Behavior and Behavior Mechanisms 0.030 0.667 3 2002 2015
dbSNP: rs1799971
rs1799971 		0.559 0.600 6 154039662 missense variant A/G snv 0.19 0.12
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		Neoplasms; Skin and Connective Tissue Diseases 0.030 1.000 3 2012 2015
dbSNP: rs1799971
rs1799971 		0.559 0.600 6 154039662 missense variant A/G snv 0.19 0.12
CUI: C0027498
Disease: Nausea and vomiting
Nausea and vomiting 		Pathological Conditions, Signs and Symptoms 0.030 0.667 3 2011 2019
dbSNP: rs1799971
rs1799971 		0.559 0.600 6 154039662 missense variant A/G snv 0.19 0.12
CUI: C0011581
Disease: Depressive disorder
Depressive disorder 		Mental Disorders 0.030 0.667 3 2002 2015
dbSNP: rs1799971
rs1799971 		0.559 0.600 6 154039662 missense variant A/G snv 0.19 0.12
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		Neoplasms; Skin and Connective Tissue Diseases 0.030 1.000 3 2012 2015