OPRM1, opioid receptor mu 1, 4988

N. diseases: 370; N. variants: 42
Source: ALL
Variant DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Disease Disease Class Score vda EI vda N. PMIDs First Ref. Last Ref.
dbSNP: rs1799971
rs1799971 		0.559 0.600 6 154039662 missense variant A/G snv 0.19 0.12
CUI: C0520909
Disease: Postoperative Nausea and Vomiting
Postoperative Nausea and Vomiting 		Pathological Conditions, Signs and Symptoms 0.030 0.667 3 2011 2018
dbSNP: rs1799971
rs1799971 		0.559 0.600 6 154039662 missense variant A/G snv 0.19 0.12
CUI: C0003469
Disease: Anxiety Disorders
Anxiety Disorders 		Mental Disorders 0.030 0.667 3 2002 2018
dbSNP: rs1799971
rs1799971 		0.559 0.600 6 154039662 missense variant A/G snv 0.19 0.12
CUI: C0003467
Disease: Anxiety
Anxiety 		Behavior and Behavior Mechanisms 0.030 0.667 3 2002 2018
dbSNP: rs17174638
rs17174638 		1.000 0.080 6 154039434 stop gained C/T snv 6.3E-03 3.1E-02
CUI: C0038580
Disease: Substance Dependence
Substance Dependence 		Chemically-Induced Disorders; Mental Disorders 0.020 0.500 2 2000 2003
dbSNP: rs1799971
rs1799971 		0.559 0.600 6 154039662 missense variant A/G snv 0.19 0.12
CUI: C0013146
Disease: Drug abuse
Drug abuse 		Chemically-Induced Disorders; Mental Disorders 0.020 1.000 2 2019 2019
dbSNP: rs1799971
rs1799971 		0.559 0.600 6 154039662 missense variant A/G snv 0.19 0.12
CUI: C0038586
Disease: Substance Use Disorders
Substance Use Disorders 		Chemically-Induced Disorders; Mental Disorders 0.020 0.500 2 2013 2018
dbSNP: rs1799971
rs1799971 		0.559 0.600 6 154039662 missense variant A/G snv 0.19 0.12
CUI: C0279626
Disease: Squamous cell carcinoma of esophagus
Squamous cell carcinoma of esophagus 		Digestive System Diseases; Neoplasms 0.020 1.000 2 2013 2017
dbSNP: rs1799971
rs1799971 		0.559 0.600 6 154039662 missense variant A/G snv 0.19 0.12
CUI: C0149931
Disease: Migraine Disorders
Migraine Disorders 		Nervous System Diseases 0.020 1.000 2 2012 2017
dbSNP: rs1799971
rs1799971 		0.559 0.600 6 154039662 missense variant A/G snv 0.19 0.12
CUI: C0027497
Disease: Nausea
Nausea 		Pathological Conditions, Signs and Symptoms 0.020 1.000 2 2013 2018
dbSNP: rs1799971
rs1799971 		0.559 0.600 6 154039662 missense variant A/G snv 0.19 0.12
CUI: C0042571
Disease: Vertigo
Vertigo 		Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases 0.020 1.000 2 2013 2018
dbSNP: rs1799971
rs1799971 		0.559 0.600 6 154039662 missense variant A/G snv 0.19 0.12
CUI: C0016053
Disease: Fibromyalgia
Fibromyalgia 		Musculoskeletal Diseases; Nervous System Diseases 0.020 1.000 2 2014 2018
dbSNP: rs1799971
rs1799971 		0.559 0.600 6 154039662 missense variant A/G snv 0.19 0.12
CUI: C0024031
Disease: Low Back Pain
Low Back Pain 		Pathological Conditions, Signs and Symptoms 0.020 1.000 2 2012 2017
dbSNP: rs1799971
rs1799971 		0.559 0.600 6 154039662 missense variant A/G snv 0.19 0.12
CUI: C0012833
Disease: Dizziness
Dizziness 		Pathological Conditions, Signs and Symptoms 0.020 1.000 2 2013 2018
dbSNP: rs1799971
rs1799971 		0.559 0.600 6 154039662 missense variant A/G snv 0.19 0.12
CUI: C0278147
Disease: Radicular pain
Radicular pain 		Pathological Conditions, Signs and Symptoms 0.020 1.000 2 2014 2017
dbSNP: rs1799971
rs1799971 		0.559 0.600 6 154039662 missense variant A/G snv 0.19 0.12
CUI: C0852733
Disease: Completed Suicide
Completed Suicide 		0.020 1.000 2 2008 2012
dbSNP: rs3778150
rs3778150 		0.925 0.080 6 154062523 intron variant T/C snv 0.17
CUI: C0019337
Disease: Heroin Dependence
Heroin Dependence 		Chemically-Induced Disorders; Mental Disorders 0.020 1.000 2 2015 2017
dbSNP: rs563649
rs563649 		1.000 0.040 6 154086832 5 prime UTR variant C/T snv 9.8E-02
CUI: C0030193
Disease: Pain
Pain 		Pathological Conditions, Signs and Symptoms 0.020 1.000 2 2009 2017
dbSNP: rs769540300
rs769540300 		0.851 0.200 6 154091047 missense variant G/A snv 1.2E-05
CUI: C0563625
Disease: Agnosia for Pain
Agnosia for Pain 		Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms 0.020 1.000 2 2008 2018
dbSNP: rs111339162
rs111339162 		1.000 0.040 6 154039596 missense variant G/A snv 2.0E-05 1.4E-04
CUI: C1842981
Disease: NEUROTICISM
NEUROTICISM 		Behavior and Behavior Mechanisms 0.010 1.000 1 2018 2018
dbSNP: rs1187761291
rs1187761291 		1.000 0.120 6 154039569 missense variant A/G snv 4.1E-06
CUI: C0563625
Disease: Agnosia for Pain
Agnosia for Pain 		Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms 0.010 < 0.001 1 2010 2010
dbSNP: rs1323040
rs1323040 		0.882 0.080 6 154010889 5 prime UTR variant A/G snv 2.1E-05
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung 		Neoplasms; Respiratory Tract Diseases 0.010 1.000 1 2019 2019
dbSNP: rs1323040
rs1323040 		0.882 0.080 6 154010889 5 prime UTR variant A/G snv 2.1E-05
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung 		Neoplasms; Respiratory Tract Diseases 0.010 1.000 1 2019 2019
dbSNP: rs1323040
rs1323040 		0.882 0.080 6 154010889 5 prime UTR variant A/G snv 2.1E-05
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		Neoplasms; Respiratory Tract Diseases 0.010 1.000 1 2019 2019
dbSNP: rs1323042
rs1323042 		6 154100709 intron variant G/T snv 0.49
CUI: C0520909
Disease: Postoperative Nausea and Vomiting
Postoperative Nausea and Vomiting 		Pathological Conditions, Signs and Symptoms 0.010 1.000 1 2014 2014
dbSNP: rs17174794
rs17174794 		1.000 6 154089975 missense variant C/G;T snv 4.1E-03
CUI: C0858353
Disease: Addicted to heroin
Addicted to heroin 		0.010 1.000 1 2013 2013