OPRM1, opioid receptor mu 1, 4988

N. diseases: 370; N. variants: 42
Source: ALL
Variant DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Disease Disease Class Score vda EI vda N. PMIDs First Ref. Last Ref.
dbSNP: rs648007
rs648007 		1.000 0.080 6 154101476 intron variant A/G snv 0.64
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		Nutritional and Metabolic Diseases; Endocrine System Diseases 0.010 1.000 1 2006 2006
dbSNP: rs6902403
rs6902403 		6 154157868 3 prime UTR variant T/C snv 0.59
CUI: C0242510
Disease: Drug usage
Drug usage 		Chemically-Induced Disorders; Mental Disorders 0.010 1.000 1 2018 2018
dbSNP: rs77114424
rs77114424 		6 154039497 missense variant G/A snv
CUI: C0030193
Disease: Pain
Pain 		Pathological Conditions, Signs and Symptoms 0.010 1.000 1 2010 2010
dbSNP: rs77114424
rs77114424 		6 154039497 missense variant G/A snv
CUI: C0150055
Disease: Chronic pain
Chronic pain 		Pathological Conditions, Signs and Symptoms 0.010 1.000 1 2010 2010
dbSNP: rs7773995
rs7773995 		1.000 0.080 6 154061232 intron variant C/T snv 0.15
CUI: C0028754
Disease: Obesity
Obesity 		Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases 0.010 1.000 1 2009 2009
dbSNP: rs9397685
rs9397685 		6 154112099 intron variant A/G snv 6.7E-03
CUI: C0520909
Disease: Postoperative Nausea and Vomiting
Postoperative Nausea and Vomiting 		Pathological Conditions, Signs and Symptoms 0.010 1.000 1 2014 2014
dbSNP: rs9478496
rs9478496 		6 154012048 intron variant T/C;G snv
CUI: C1305855
Disease: Body mass index
Body mass index 		0.700 1.000 1 2019 2019
dbSNP: rs774507706
rs774507706 		1.000 0.080 6 154091093 missense variant A/G snv 4.0E-06
CUI: C0028043
Disease: Nicotine Dependence
Nicotine Dependence 		Chemically-Induced Disorders; Mental Disorders 0.010 1.000 1 2011 2011
dbSNP: rs199953844
rs199953844 		6 154039650 missense variant C/A;T snv 4.0E-06; 1.2E-04
CUI: C0549393
Disease: Alcohol problem
Alcohol problem 		0.010 1.000 1 2014 2014
dbSNP: rs199953844
rs199953844 		6 154039650 missense variant C/A;T snv 4.0E-06; 1.2E-04
CUI: C1510472
Disease: Drug Dependence
Drug Dependence 		Chemically-Induced Disorders; Mental Disorders 0.010 1.000 1 2014 2014
dbSNP: rs1187761291
rs1187761291 		1.000 0.120 6 154039569 missense variant A/G snv 4.1E-06
CUI: C0563625
Disease: Agnosia for Pain
Agnosia for Pain 		Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms 0.010 < 0.001 1 2010 2010
dbSNP: rs1799972
rs1799972 		0.827 0.080 6 154039561 missense variant C/A;G;T snv 4.1E-06; 1.7E-02
CUI: C0524662
Disease: Opiate Addiction
Opiate Addiction 		Chemically-Induced Disorders; Mental Disorders 0.010 < 0.001 1 2007 2007
dbSNP: rs1799972
rs1799972 		0.827 0.080 6 154039561 missense variant C/A;G;T snv 4.1E-06; 1.7E-02
CUI: C0242510
Disease: Drug usage
Drug usage 		Chemically-Induced Disorders; Mental Disorders 0.010 1.000 1 2012 2012
dbSNP: rs1799972
rs1799972 		0.827 0.080 6 154039561 missense variant C/A;G;T snv 4.1E-06; 1.7E-02
CUI: C0038580
Disease: Substance Dependence
Substance Dependence 		Chemically-Induced Disorders; Mental Disorders 0.010 < 0.001 1 2012 2012
dbSNP: rs1799972
rs1799972 		0.827 0.080 6 154039561 missense variant C/A;G;T snv 4.1E-06; 1.7E-02
CUI: C0028768
Disease: Obsessive-Compulsive Disorder
Obsessive-Compulsive Disorder 		Mental Disorders 0.010 1.000 1 2004 2004
dbSNP: rs1799972
rs1799972 		0.827 0.080 6 154039561 missense variant C/A;G;T snv 4.1E-06; 1.7E-02
CUI: C0740858
Disease: Substance abuse problem
Substance abuse problem 		Chemically-Induced Disorders; Mental Disorders 0.010 1.000 1 2007 2007
dbSNP: rs1799972
rs1799972 		0.827 0.080 6 154039561 missense variant C/A;G;T snv 4.1E-06; 1.7E-02
CUI: C3854222
Disease: Human immunodeficiency virus (HIV) II infection category B1
Human immunodeficiency virus (HIV) II infection category B1 		0.010 1.000 1 2012 2012
dbSNP: rs677830
rs677830 		6 154107531 stop gained C/A;G;T snv 6.6E-06; 6.6E-06; 0.19
CUI: C0030193
Disease: Pain
Pain 		Pathological Conditions, Signs and Symptoms 0.010 1.000 1 2016 2016
dbSNP: rs199682734
rs199682734 		6 154118718 synonymous variant C/T snv 8.1E-06 7.0E-06
CUI: C0015672
Disease: Fatigue
Fatigue 		Pathological Conditions, Signs and Symptoms 0.010 1.000 1 2008 2008
dbSNP: rs769540300
rs769540300 		0.851 0.200 6 154091047 missense variant G/A snv 1.2E-05
CUI: C0563625
Disease: Agnosia for Pain
Agnosia for Pain 		Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms 0.020 1.000 2 2008 2018
dbSNP: rs769540300
rs769540300 		0.851 0.200 6 154091047 missense variant G/A snv 1.2E-05
CUI: C0150055
Disease: Chronic pain
Chronic pain 		Pathological Conditions, Signs and Symptoms 0.010 1.000 1 2010 2010
dbSNP: rs769540300
rs769540300 		0.851 0.200 6 154091047 missense variant G/A snv 1.2E-05
CUI: C0003467
Disease: Anxiety
Anxiety 		Behavior and Behavior Mechanisms 0.010 1.000 1 2004 2004
dbSNP: rs769540300
rs769540300 		0.851 0.200 6 154091047 missense variant G/A snv 1.2E-05
CUI: C0233477
Disease: Dysphoric mood
Dysphoric mood 		Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms 0.010 1.000 1 2004 2004
dbSNP: rs769540300
rs769540300 		0.851 0.200 6 154091047 missense variant G/A snv 1.2E-05
CUI: C0003469
Disease: Anxiety Disorders
Anxiety Disorders 		Mental Disorders 0.010 1.000 1 2004 2004
dbSNP: rs769540300
rs769540300 		0.851 0.200 6 154091047 missense variant G/A snv 1.2E-05
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic 		Chemically-Induced Disorders; Mental Disorders 0.010 1.000 1 2004 2004