|
rs6671141
|
PRDX6;LOC100506023
|
Blood Protein Measurement
|
T |
0.700 |
GeneticVariation |
GWASCAT |
Co-regulatory networks of human serum proteins link genetics to disease.
|
30072576 |
2018 |
|
rs10912580
|
TNFSF4;LOC100506023
|
Breast Carcinoma
|
|
0.010 |
GeneticVariation |
BEFREE |
The haplotype analysis showed that haplotype A(rs844648)A(rs10912580) was significantly associated with breast cancer, even after 10,000 permutations for haplotypes in block only (P = 0.0003).
|
22870213 |
2012 |
|
rs844648
|
TNFSF4;LOC100506023
|
Breast Carcinoma
|
|
0.010 |
GeneticVariation |
BEFREE |
The haplotype analysis showed that haplotype A(rs844648)A(rs10912580) was significantly associated with breast cancer, even after 10,000 permutations for haplotypes in block only (P = 0.0003).
|
22870213 |
2012 |
|
rs10489265
|
TNFSF4;LOC100506023
|
Encephalitis, St. Louis
|
|
0.010 |
GeneticVariation |
BEFREE |
To replicate the association, two single-nucleotide polymorphisms (SNPs: rs2205960 and rs10489265) were genotyped in 814 SLE patients.
|
23936824 |
2013 |
|
rs1099448
|
TNFSF4;LOC100506023
|
Eosinophil count procedure
|
|
0.700 |
GeneticVariation |
GWASCAT |
Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
|
30595370 |
2019 |
|
rs10489265
|
TNFSF4;LOC100506023
|
Lupus Erythematosus
|
|
0.010 |
GeneticVariation |
BEFREE |
The SNPs of TNFSF4 were associated with renal involvement in lupus patients from the Chinese population (P values for rs2205960 and rs10489265 were 0.014 and 0.005 in additive model, resp.).
|
23936824 |
2013 |
|
rs10489265
|
TNFSF4;LOC100506023
|
Lupus Erythematosus, Discoid
|
|
0.010 |
GeneticVariation |
BEFREE |
The SNPs of TNFSF4 were associated with renal involvement in lupus patients from the Chinese population (P values for rs2205960 and rs10489265 were 0.014 and 0.005 in additive model, resp.).
|
23936824 |
2013 |
|
rs10798269
|
TNFSF4;LOC100506023
|
Lupus Erythematosus, Systemic
|
|
0.810 |
GeneticVariation |
GWASDB |
Aside from the expected strong association between SLE and the HLA region on chromosome 6p21 and the previously confirmed non-HLA locus IRF5 on chromosome 7q32, we found evidence of association with replication (1.1 x 10(-7) < P(overall) < 1.6 x 10(-23); odds ratio = 0.82-1.62) in four regions: 16p11.2 (ITGAM), 11p15.5 (KIAA1542), 3p14.3 (PXK) and 1q25.1 (rs10798269).
|
18204446 |
2008 |
|
rs10798269
|
TNFSF4;LOC100506023
|
Lupus Erythematosus, Systemic
|
|
0.810 |
GeneticVariation |
BEFREE |
Aside from the expected strong association between SLE and the HLA region on chromosome 6p21 and the previously confirmed non-HLA locus IRF5 on chromosome 7q32, we found evidence of association with replication (1.1 x 10(-7) < P(overall) < 1.6 x 10(-23); odds ratio = 0.82-1.62) in four regions: 16p11.2 (ITGAM), 11p15.5 (KIAA1542), 3p14.3 (PXK) and 1q25.1 (rs10798269).
|
18204446 |
2008 |
|
rs10798269
|
TNFSF4;LOC100506023
|
Lupus Erythematosus, Systemic
|
|
0.810 |
GeneticVariation |
GWASCAT |
Aside from the expected strong association between SLE and the HLA region on chromosome 6p21 and the previously confirmed non-HLA locus IRF5 on chromosome 7q32, we found evidence of association with replication (1.1 x 10(-7) < P(overall) < 1.6 x 10(-23); odds ratio = 0.82-1.62) in four regions: 16p11.2 (ITGAM), 11p15.5 (KIAA1542), 3p14.3 (PXK) and 1q25.1 (rs10798269).
|
18204446 |
2008 |
|
rs704840
|
TNFSF4;LOC100506023
|
Lupus Erythematosus, Systemic
|
|
0.810 |
GeneticVariation |
GWASCAT |
A systemic sclerosis and systemic lupus erythematosus pan-meta-GWAS reveals new shared susceptibility loci.
|
23740937 |
2013 |
|
rs704840
|
TNFSF4;LOC100506023
|
Lupus Erythematosus, Systemic
|
|
0.810 |
GeneticVariation |
GWASDB |
Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in Asians.
|
23273568 |
2013 |
|
rs704840
|
TNFSF4;LOC100506023
|
Lupus Erythematosus, Systemic
|
G |
0.810 |
GeneticVariation |
GWASCAT |
Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus.
|
26502338 |
2015 |
|
rs704840
|
TNFSF4;LOC100506023
|
Lupus Erythematosus, Systemic
|
|
0.810 |
GeneticVariation |
BEFREE |
Significant association of m</span>inor G allele of rs704840</span> with SLE was also observed in Chinese (P = 0.03, OR = 1.26, 95% CI: 1.02-1.56).
|
27519474 |
2016 |
|
rs10489265
|
TNFSF4;LOC100506023
|
Lupus Erythematosus, Systemic
|
|
0.720 |
GeneticVariation |
BEFREE |
The SNPs of TNFSF4 were associated with renal involvement in lupus patients from the Chinese population (P values for rs2205960 and rs10489265 were 0.014 and 0.005 in additive model, resp.).
|
23936824 |
2013 |
|
rs10489265
|
TNFSF4;LOC100506023
|
Lupus Erythematosus, Systemic
|
|
0.720 |
GeneticVariation |
GWASDB |
Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in Asians.
|
23273568 |
2013 |
|
rs10489265
|
TNFSF4;LOC100506023
|
Lupus Erythematosus, Systemic
|
|
0.720 |
GeneticVariation |
BEFREE |
Meta-analysis revealed an association between the minor alleles of rs1234315 and rs10489265 of TNFSF4 and SLE in Asians (OR=1.366, 95% CI=1.295-1.440, p<1.0×10(-9); OR=1.463, 95% CI=1.208-1.771, p=9.7×10(-5)).
|
22820624 |
2012 |
|
rs844648
|
TNFSF4;LOC100506023
|
Lupus Erythematosus, Systemic
|
|
0.720 |
GeneticVariation |
GWASDB |
Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in Asians.
|
23273568 |
2013 |
|
rs844648
|
TNFSF4;LOC100506023
|
Lupus Erythematosus, Systemic
|
|
0.720 |
GeneticVariation |
BEFREE |
No association was found between the rs844644 and rs844648 polymorphisms and SLE.
|
22850862 |
2013 |
|
rs844648
|
TNFSF4;LOC100506023
|
Lupus Erythematosus, Systemic
|
|
0.720 |
GeneticVariation |
BEFREE |
In TNFSF4, rs2205960 was associated with SLE independently from the effect of rs844648 (P=6.26 x 10(-3)), but not vice versa (P=0.55).
|
19357697 |
2009 |
|
rs1012507
|
TNFSF4;LOC100506023
|
Lupus Erythematosus, Systemic
|
|
0.700 |
GeneticVariation |
GWASDB |
Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in Asians.
|
23273568 |
2013 |
|
rs10753074
|
TNFSF4;LOC100506023
|
Lupus Erythematosus, Systemic
|
T |
0.700 |
GeneticVariation |
GWASCAT |
Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus.
|
26502338 |
2015 |
|
rs10912578
|
TNFSF4;LOC100506023
|
Lupus Erythematosus, Systemic
|
|
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide association meta-analysis in Chinese and European individuals identifies ten new loci associated with systemic lupus erythematosus.
|
27399966 |
2016 |
|
rs10912578
|
TNFSF4;LOC100506023
|
Lupus Erythematosus, Systemic
|
A |
0.700 |
GeneticVariation |
GWASCAT |
Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus.
|
26502338 |
2015 |
|
rs12736195
|
TNFSF4;LOC100506023
|
Lupus Erythematosus, Systemic
|
|
0.700 |
GeneticVariation |
GWASCAT |
Genome-Wide Association Study in an Amerindian Ancestry Population Reveals Novel Systemic Lupus Erythematosus Risk Loci and the Role of European Admixture.
|
26606652 |
2016 |