GCKR, glucokinase regulator, 2646

N. diseases: 136; N. variants: 23
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1260326
rs1260326
Entrez Id: 2646
Gene Symbol: GCKR
GCKR
CUI: C0020557
Disease:
Hypertriglyceridemia 		0.820 GeneticVariation GWASDB Genomic study in Mexicans identifies a new locus for triglycerides and refines European lipid loci. 23505323 2013
dbSNP: rs1260326
rs1260326
Entrez Id: 2646
Gene Symbol: GCKR
GCKR
CUI: C0020557
Disease:
Hypertriglyceridemia 		0.820 GeneticVariation BEFREE Recently, the single nucleotide polymorphism (SNP) identified as rs1260326, in the glucokinase regulatory protein (GCKR), was associated with hypertriglyceridemia in adults. 22105854 2012
dbSNP: rs1260326
rs1260326
Entrez Id: 2646
Gene Symbol: GCKR
GCKR
CUI: C0020557
Disease:
Hypertriglyceridemia 		T 0.820 GeneticVariation GWASDB Excess of rare variants in genes identified by genome-wide association study of hypertriglyceridemia. 20657596 2010
dbSNP: rs1260326
rs1260326
Entrez Id: 2646
Gene Symbol: GCKR
GCKR
CUI: C0020557
Disease:
Hypertriglyceridemia 		T 0.820 GeneticVariation GWASCAT Excess of rare variants in genes identified by genome-wide association study of hypertriglyceridemia. 20657596 2010
dbSNP: rs780094
rs780094
Entrez Id: 2646
Gene Symbol: GCKR
GCKR
CUI: C0010068
Disease:
Coronary heart disease 		0.810 GeneticVariation GWASCAT Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases. 27790247 2016
dbSNP: rs780094
rs780094
Entrez Id: 2646
Gene Symbol: GCKR
GCKR
CUI: C0010068
Disease:
Coronary heart disease 		0.810 GeneticVariation GWASDB Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project. 21347282 2011
dbSNP: rs780094
rs780094
Entrez Id: 2646
Gene Symbol: GCKR
GCKR
CUI: C0010068
Disease:
Coronary heart disease 		0.810 GeneticVariation BEFREE Our findings indicate rs780094 has independent associations with multiple metabolic traits as well as incident diabetes, but not incident CHD or stroke. 20661421 2010
dbSNP: rs1260326
rs1260326
Entrez Id: 2646
Gene Symbol: GCKR
GCKR
CUI: C0202239
Disease:
Uric acid measurement (procedure) 		T 0.800 GeneticVariation GWASCAT Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels. 31578528 2019
dbSNP: rs1260326
rs1260326
Entrez Id: 2646
Gene Symbol: GCKR
GCKR
CUI: C0003868
Disease:
Arthritis, Gouty 		0.800 GeneticVariation GWASCAT Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels. 31578528 2019
dbSNP: rs1260326
rs1260326
Entrez Id: 2646
Gene Symbol: GCKR
GCKR
CUI: C0017654
Disease:
Glomerular Filtration Rate 		T 0.800 GeneticVariation GWASCAT Mapping eGFR loci to the renal transcriptome and phenome in the VA Million Veteran Program. 31451708 2019
dbSNP: rs1260326
rs1260326
Entrez Id: 2646
Gene Symbol: GCKR
GCKR
CUI: C0017654
Disease:
Glomerular Filtration Rate 		C 0.800 GeneticVariation GWASCAT Trans-ethnic kidney function association study reveals putative causal genes and effects on kidney-specific disease aetiologies. 30604766 2019
dbSNP: rs1260326
rs1260326
Entrez Id: 2646
Gene Symbol: GCKR
GCKR
CUI: C0018099
Disease:
Gout 		0.800 GeneticVariation GWASCAT Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels. 31578528 2019
dbSNP: rs1260326
rs1260326
Entrez Id: 2646
Gene Symbol: GCKR
GCKR
CUI: C1445957
Disease:
Serum total cholesterol measurement 		0.800 GeneticVariation GWASCAT Genetic analyses of diverse populations improves discovery for complex traits. 31217584 2019
dbSNP: rs1260326
rs1260326
Entrez Id: 2646
Gene Symbol: GCKR
GCKR
CUI: C0201657
Disease:
C-reactive protein measurement 		0.800 GeneticVariation GWASCAT Genetic analyses of diverse populations improves discovery for complex traits. 31217584 2019
dbSNP: rs1260326
rs1260326
Entrez Id: 2646
Gene Symbol: GCKR
GCKR
CUI: C0428568
Disease:
Fasting blood glucose measurement 		0.800 GeneticVariation GWASCAT Genetic analyses of diverse populations improves discovery for complex traits. 31217584 2019
dbSNP: rs1260326
rs1260326
Entrez Id: 2646
Gene Symbol: GCKR
GCKR
CUI: C0202236
Disease:
Triglycerides measurement 		0.800 GeneticVariation GWASCAT Genome-wide association study of blood lipids in Indians confirms universality of established variants. 30911093 2019
dbSNP: rs1260326
rs1260326
Entrez Id: 2646
Gene Symbol: GCKR
GCKR
CUI: C0202239
Disease:
Uric acid measurement (procedure) 		T 0.800 GeneticVariation GWASCAT Genome-wide meta-analysis identifies multiple novel loci associated with serum uric acid levels in Japanese individuals. 30993211 2019
dbSNP: rs1260326
rs1260326
Entrez Id: 2646
Gene Symbol: GCKR
GCKR
CUI: C0202236
Disease:
Triglycerides measurement 		T 0.800 GeneticVariation GWASCAT Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids. 30926973 2019
dbSNP: rs1260326
rs1260326
Entrez Id: 2646
Gene Symbol: GCKR
GCKR
CUI: C0202236
Disease:
Triglycerides measurement 		0.800 GeneticVariation GWASCAT Genetic analyses of diverse populations improves discovery for complex traits. 31217584 2019
dbSNP: rs1260326
rs1260326
Entrez Id: 2646
Gene Symbol: GCKR
GCKR
CUI: C0202236
Disease:
Triglycerides measurement 		T 0.800 GeneticVariation GWASCAT Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity. 30670697 2019
dbSNP: rs1260326
rs1260326
Entrez Id: 2646
Gene Symbol: GCKR
GCKR
CUI: C0428568
Disease:
Fasting blood glucose measurement 		0.800 GeneticVariation GWASCAT Pleiotropy informed adaptive association test of multiple traits using genome-wide association study summary data. 31021400 2019
dbSNP: rs780092
rs780092
Entrez Id: 2646
Gene Symbol: GCKR
GCKR
CUI: C0202236
Disease:
Triglycerides measurement 		0.800 GeneticVariation GWASCAT The Korea Biobank Array: Design and Identification of Coding Variants Associated with Blood Biochemical Traits. 30718733 2019
dbSNP: rs780093
rs780093
Entrez Id: 2646
Gene Symbol: GCKR
GCKR
CUI: C0202236
Disease:
Triglycerides measurement 		0.800 GeneticVariation GWASCAT Genetic analyses of diverse populations improves discovery for complex traits. 31217584 2019
dbSNP: rs780093
rs780093
Entrez Id: 2646
Gene Symbol: GCKR
GCKR
CUI: C1445957
Disease:
Serum total cholesterol measurement 		0.800 GeneticVariation GWASCAT Genetic analyses of diverse populations improves discovery for complex traits. 31217584 2019
dbSNP: rs780094
rs780094
Entrez Id: 2646
Gene Symbol: GCKR
GCKR
CUI: C0202236
Disease:
Triglycerides measurement 		0.800 GeneticVariation GWASCAT Genetic analyses of diverse populations improves discovery for complex traits. 31217584 2019