|
rs2292832
|
GPC1;MIR149;LOC100130449
|
Coronary heart disease
|
|
0.020 |
GeneticVariation |
BEFREE |
We conducted a three-stage case-control study of CHD in Chinese to test our hypothesis by genotyping miR-196a2 rs11614913 and three other pre-miRNA SNPs (miR-146a rs2910164, miR-149 rs2292832, and miR-499 rs3746444) in 1,324 CHD cases and 1,783 non-CHD controls.
|
19514064 |
2009 |
|
rs2292832
|
GPC1;MIR149;LOC100130449
|
Squamous cell carcinoma of the head and neck
|
|
0.010 |
GeneticVariation |
BEFREE |
The authors genotyped 4 common polymorphisms in pre-miRNAs: Homo sapiens miRNA 146a (hsa-mir-146a) (reference SNP 2910164 [rs2910164]; guanine to cytosine [G→C]), hsa-mir-149 (rs2292832; guanine to thymine [G→T]), hsa-mir-196a2 (rs11614913; C→T), and hsa-mir-499 (rs3746444; adenine to guanine [A→G]) in 1109 patients with SCCHN (cases) and in 1130 cancer-free patients (controls) in a non-Hispanic white population that was frequency-matched by age and sex.
|
20549817 |
2010 |
|
rs2292832
|
GPC1;MIR149;LOC100130449
|
Anthracosis
|
|
0.010 |
GeneticVariation |
BEFREE |
These results suggest that miR-149 rs2292832 polymorphism is involved in susceptibility to developing CWP.
|
19881472 |
2010 |
|
rs2292832
|
GPC1;MIR149;LOC100130449
|
Malignant Neoplasms
|
|
0.100 |
GeneticVariation |
BEFREE |
Here, we evaluated 101 paired samples (cancer and normal tissues) from non-small cell lung carcinoma (NSCLC) patients to study the genotype distribution of single nucleotide polymorphisms (SNPs) in miR-146a (rs2910164 C-G), miR-149 (rs2292832 C-T), miR-196a2 (rs11614913 C-T) and miR-499 (rs3746444 G-A) and their influence on the expression of respective miRNAs.
|
21902575 |
2011 |
|
rs2292832
|
GPC1;MIR149;LOC100130449
|
Primary malignant neoplasm
|
|
0.100 |
GeneticVariation |
BEFREE |
Here, we evaluated 101 paired samples (cancer and normal tissues) from non-small cell lung carcinoma (NSCLC) patients to study the genotype distribution of single nucleotide polymorphisms (SNPs) in miR-146a (rs2910164 C-G), miR-149 (rs2292832 C-T), miR-196a2 (rs11614913 C-T) and miR-499 (rs3746444 G-A) and their influence on the expression of respective miRNAs.
|
21902575 |
2011 |
|
rs2292832
|
GPC1;MIR149;LOC100130449
|
Non-Small Cell Lung Carcinoma
|
|
0.020 |
GeneticVariation |
BEFREE |
Here, we evaluated 101 paired samples (cancer and normal tissues) from non-small cell lung carcinoma (NSCLC) patients to study the genotype distribution of single nucleotide polymorphisms (SNPs) in miR-146a (rs2910164 C-G), miR-149 (rs2292832 C-T), miR-196a2 (rs11614913 C-T) and miR-499 (rs3746444 G-A) and their influence on the expression of respective miRNAs.
|
21902575 |
2011 |
|
rs2292832
|
GPC1;MIR149;LOC100130449
|
Asthma
|
|
0.020 |
GeneticVariation |
BEFREE |
Our data indicate that rs2910164G/C and rs2292832C/T may play a role in the development of asthma.
|
21663520 |
2011 |
|
rs2292832
|
GPC1;MIR149;LOC100130449
|
Primary malignant neoplasm
|
|
0.100 |
GeneticVariation |
BEFREE |
The association between four genetic variants in microRNAs (rs11614913, rs2910164, rs3746444, rs2292832) and cancer risk: evidence from published studies.
|
23155448 |
2012 |
|
rs2292832
|
GPC1;MIR149;LOC100130449
|
Malignant Neoplasms
|
|
0.100 |
GeneticVariation |
BEFREE |
The association between four genetic variants in microRNAs (rs11614913, rs2910164, rs3746444, rs2292832) and cancer risk: evidence from published studies.
|
23155448 |
2012 |
|
rs2292832
|
GPC1;MIR149;LOC100130449
|
Malignant Neoplasms
|
|
0.100 |
GeneticVariation |
BEFREE |
The present study was aimed to investigate the association between four highly studied miRNA polymorphisms (mir-146a rs2910164, mir-196a2 rs11614913, mir-149 rs2292832 and mir-499 rs3746444) and cancer risk by using a two-sided meta-analytic approach.
|
23226435 |
2012 |
|
rs2292832
|
GPC1;MIR149;LOC100130449
|
Primary malignant neoplasm
|
|
0.100 |
GeneticVariation |
BEFREE |
The present study was aimed to investigate the association between four highly studied miRNA polymorphisms (mir-146a rs2910164, mir-196a2 rs11614913, mir-149 rs2292832 and mir-499 rs3746444) and cancer risk by using a two-sided meta-analytic approach.
|
23226435 |
2012 |
|
rs2292832
|
GPC1;MIR149;LOC100130449
|
Colorectal Carcinoma
|
|
0.080 |
GeneticVariation |
BEFREE |
Although recent studies focused on various diseases that harbor the miR-146aC>G (rs2910164), 149C>T (rs2292832), 196a2C>T (rs11614913), and 499A>G (rs3746444) polymorphisms, the role of miRNA genetic variants in colorectal cancer is still unknown.
|
22161766 |
2012 |
|
rs2292832
|
GPC1;MIR149;LOC100130449
|
Colorectal Carcinoma
|
|
0.080 |
GeneticVariation |
BEFREE |
The SNPs of rs2292832 and rs2043556 might be able to modify the susceptibility to male gastric and colorectal cancers, respectively.
|
21976437 |
2012 |
|
rs2292832
|
GPC1;MIR149;LOC100130449
|
Breast Carcinoma
|
|
0.050 |
GeneticVariation |
BEFREE |
To explore the relevance of miRNA polymorphisms and female physiological characteristics to breast cancer risk, SNPs located within hsa-miR-605 (rs2043556), hsa-miR-149 (rs2292832), hsa-miR-27a (rs895819), hsa-miR-196a-2 (rs11614913) and hsa-miR-618 (rs2682818) were selected, and their associations with breast cancer risk were analysed.
|
22074121 |
2012 |
|
rs2292832
|
GPC1;MIR149;LOC100130449
|
Malignant neoplasm of breast
|
|
0.050 |
GeneticVariation |
BEFREE |
To explore the relevance of miRNA polymorphisms and female physiological characteristics to breast cancer risk, SNPs located within hsa-miR-605 (rs2043556), hsa-miR-149 (rs2292832), hsa-miR-27a (rs895819), hsa-miR-196a-2 (rs11614913) and hsa-miR-618 (rs2682818) were selected, and their associations with breast cancer risk were analysed.
|
22074121 |
2012 |
|
rs2292832
|
GPC1;MIR149;LOC100130449
|
Malignant neoplasm of gastrointestinal tract
|
|
0.030 |
GeneticVariation |
BEFREE |
To explore the associations of SNPs within hsa-miR-605 (rs2043556) and hsa-miR-149 (rs2292832) and lifestyle-related factors with gastrointestinal cancer, a case-control study including 762 cases and 757 controls was conducted.
|
21976437 |
2012 |
|
rs2292832
|
GPC1;MIR149;LOC100130449
|
Malignant neoplasm of colon and/or rectum
|
|
0.030 |
GeneticVariation |
BEFREE |
Although recent studies focused on various diseases that harbor the miR-146aC>G (rs2910164), 149C>T (rs2292832), 196a2C>T (rs11614913), and 499A>G (rs3746444) polymorphisms, the role of miRNA genetic variants in colorectal cancer is still unknown.
|
22161766 |
2012 |
|
rs2292832
|
GPC1;MIR149;LOC100130449
|
Malignant neoplasm of colon and/or rectum
|
|
0.030 |
GeneticVariation |
BEFREE |
Marginally significant associations were found both for hsa-miR-149 rs2292832 with gastric cancer risk (TC + CC vs. TT, OR = 0.68, 95% CI: 0.44-1.04) and for hsa-miR-605 rs2043556 with colorectal cancer risk (AG + GG vs. AA, OR = 0.70, 95% CI: 0.48-1.02) in males.
|
21976437 |
2012 |
|
rs2292832
|
GPC1;MIR149;LOC100130449
|
Malignant Neoplasms
|
|
0.100 |
GeneticVariation |
BEFREE |
For the rs2292832 polymorphism, the results showed no significant risk association in both overall pooled analysis and subgroup of cancer types, smoking status, gender and tea drinking status in the Chinese population.
|
23725137 |
2013 |
|
rs2292832
|
GPC1;MIR149;LOC100130449
|
Malignant Neoplasms
|
|
0.100 |
GeneticVariation |
BEFREE |
In summary, miR-196a2 rs11614913, miR-146a rs2910164, and miR-499 rs3746444 are risk factors for cancer development, whereas mir-149 rs2292832 and miR-27a rs895919 are not associated with cancer risk.
|
24278149 |
2013 |
|
rs2292832
|
GPC1;MIR149;LOC100130449
|
Primary malignant neoplasm
|
|
0.100 |
GeneticVariation |
BEFREE |
For the rs2292832 polymorphism, the results showed no significant risk association in both overall pooled analysis and subgroup of cancer types, smoking status, gender and tea drinking status in the Chinese population.
|
23725137 |
2013 |
|
rs2292832
|
GPC1;MIR149;LOC100130449
|
Malignant Neoplasms
|
|
0.100 |
GeneticVariation |
BEFREE |
Results of this meta-analysis suggest that the hsa-miR-149 rs2292832 polymorphism is not associated with cancer risk in spite of the potentially protective role of C allele in hepatocellular carcinoma and male gastric cancer.
|
24040059 |
2013 |
|
rs2292832
|
GPC1;MIR149;LOC100130449
|
Primary malignant neoplasm
|
|
0.100 |
GeneticVariation |
BEFREE |
Results of this meta-analysis suggest that the hsa-miR-149 rs2292832 polymorphism is not associated with cancer risk in spite of the potentially protective role of C allele in hepatocellular carcinoma and male gastric cancer.
|
24040059 |
2013 |
|
rs2292832
|
GPC1;MIR149;LOC100130449
|
Primary malignant neoplasm
|
|
0.100 |
GeneticVariation |
BEFREE |
In summary, miR-196a2 rs11614913, miR-146a rs2910164, and miR-499 rs3746444 are risk factors for cancer development, whereas mir-149 rs2292832 and miR-27a rs895919 are not associated with cancer risk.
|
24278149 |
2013 |
|
rs2292832
|
GPC1;MIR149;LOC100130449
|
Liver carcinoma
|
|
0.080 |
GeneticVariation |
BEFREE |
Results of this meta-analysis suggest that the hsa-miR-149 rs2292832 polymorphism is not associated with cancer risk in spite of the potentially protective role of C allele in hepatocellular carcinoma and male gastric cancer.
|
24040059 |
2013 |