|
rs2292832
|
GPC1;MIR149;LOC100130449
|
Liver carcinoma
|
|
0.080 |
GeneticVariation |
BEFREE |
And hsa-<i>mir-149</i> rs2292832 was found to be associated with a decreased HBV-related HCC risk in the dominant and recessive models.
|
29976775 |
2018 |
|
rs2292832
|
GPC1;MIR149;LOC100130449
|
Liver carcinoma
|
|
0.080 |
GeneticVariation |
BEFREE |
To evaluate the association between four common miRNAs (miR-146a rs2910164; miR-149 rs2292832; miR-196a2 rs11614913 and miR-499 rs3746444) and HCC risk, an updated meta-analysis was performed.
|
28499985 |
2017 |
|
rs2292832
|
GPC1;MIR149;LOC100130449
|
Colorectal Carcinoma
|
|
0.080 |
GeneticVariation |
BEFREE |
However, polymorphisms of miR-149 (rs2292832; CT vs TT: odds ratio [OR] = 0.816, 95% confidence interval [CI] = 0.691-0.963; CC+CT vs TT: OR = 0.834, 95%CI = 0.715-0.972) and pre-miR-27a (rs895819; GG vs AA: OR = 1.534, 95%CI = 1.148-2.049; GG+AG vs AA: OR = 1.324, 95%CI = 1.066-1.645) were found to be associated with CRC in our analysis.
|
27706637 |
2016 |
|
rs2292832
|
GPC1;MIR149;LOC100130449
|
Liver carcinoma
|
|
0.080 |
GeneticVariation |
BEFREE |
Our meta-analysis supports that the MIR-149 gene rs2292832 polymorphism contributed to the risk of HCC from currently available evidence.
|
27348444 |
2016 |
|
rs2292832
|
GPC1;MIR149;LOC100130449
|
Colorectal Carcinoma
|
|
0.080 |
GeneticVariation |
BEFREE |
This meta-analysis showed that rs2910164 and rs2292832 may increase the risk of CRC.
|
26078942 |
2015 |
|
rs2292832
|
GPC1;MIR149;LOC100130449
|
Liver carcinoma
|
|
0.080 |
GeneticVariation |
BEFREE |
In this research, we investigated the role of miR- 149 (rs2292832) and miR-101-1 (rs7536540) with HCC progression in Thai population.
|
26434859 |
2015 |
|
rs2292832
|
GPC1;MIR149;LOC100130449
|
Liver carcinoma
|
|
0.080 |
GeneticVariation |
BEFREE |
Predictive role of miR-146a rs2910164 (C>G), miR-149 rs2292832 (T>C), miR-196a2 rs11614913 (T>C) and miR-499 rs3746444 (T>C) in the development of hepatocellular carcinoma.
|
26823863 |
2015 |
|
rs2292832
|
GPC1;MIR149;LOC100130449
|
Liver carcinoma
|
|
0.080 |
GeneticVariation |
BEFREE |
Association study of miR‑149 rs2292832 and miR‑608 rs4919510 and the risk of hepatocellular carcinoma in a large‑scale population.
|
25190221 |
2014 |
|
rs2292832
|
GPC1;MIR149;LOC100130449
|
Colorectal Carcinoma
|
|
0.080 |
GeneticVariation |
BEFREE |
These findings supported that the miR-196a2 rs11614913 and miR-149 rs2292832 polymorphisms may contribute to susceptibility to CRC.
|
24568449 |
2014 |
|
rs2292832
|
GPC1;MIR149;LOC100130449
|
Liver carcinoma
|
|
0.080 |
GeneticVariation |
BEFREE |
Results of this meta-analysis suggest that the hsa-miR-149 rs2292832 polymorphism is not associated with cancer risk in spite of the potentially protective role of C allele in hepatocellular carcinoma and male gastric cancer.
|
24040059 |
2013 |
|
rs2292832
|
GPC1;MIR149;LOC100130449
|
Colorectal Carcinoma
|
|
0.080 |
GeneticVariation |
BEFREE |
We genotyped four common polymorphisms (i.e., rs11614913, rs3746444, rs2910164, and rs2292832) in pre-miRNAs of 353 CRC patients and 540 healthy controls to investigate the association between the SNPs and the risk of CRC using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) assay.
|
23728616 |
2013 |
|
rs2292832
|
GPC1;MIR149;LOC100130449
|
Colorectal Carcinoma
|
|
0.080 |
GeneticVariation |
BEFREE |
Although recent studies focused on various diseases that harbor the miR-146aC>G (rs2910164), 149C>T (rs2292832), 196a2C>T (rs11614913), and 499A>G (rs3746444) polymorphisms, the role of miRNA genetic variants in colorectal cancer is still unknown.
|
22161766 |
2012 |
|
rs2292832
|
GPC1;MIR149;LOC100130449
|
Colorectal Carcinoma
|
|
0.080 |
GeneticVariation |
BEFREE |
The SNPs of rs2292832 and rs2043556 might be able to modify the susceptibility to male gastric and colorectal cancers, respectively.
|
21976437 |
2012 |
|
rs2292832
|
GPC1;MIR149;LOC100130449
|
Malignant neoplasm of breast
|
|
0.050 |
GeneticVariation |
BEFREE |
In conclusion, the rs2292832 polymorphism was significantly associated with increased breast cancer</span> risk, and the rs895819 polymorphism contributes to the susceptibility of colorectal and breast cancer.
|
26993779 |
2016 |
|
rs2292832
|
GPC1;MIR149;LOC100130449
|
Breast Carcinoma
|
|
0.050 |
GeneticVariation |
BEFREE |
In conclusion, the rs2292832 polymorphism was significantly associated with increased breast cancer</span> risk, and the rs895819 polymorphism contributes to the susceptibility of colorectal and breast cancer.
|
26993779 |
2016 |
|
rs2292832
|
GPC1;MIR149;LOC100130449
|
Breast Carcinoma
|
|
0.050 |
GeneticVariation |
BEFREE |
However, there was no association between rs2292832 (miR-149) polymorphism and BC susceptibility.
|
25483824 |
2015 |
|
rs2292832
|
GPC1;MIR149;LOC100130449
|
Breast Carcinoma
|
|
0.050 |
GeneticVariation |
BEFREE |
The data showed that the 3746444 GG was associated with increased breast cancer risk (adjusted odds ratio (OR) = 1.71, 95 % confidence interval (CI) = 1.16-2.52) and that rs2292832 CC (adjusted OR = 0.54, 95 % CI = 0.34-0.85) was associated with decreased breast cancer risk.
|
25613069 |
2015 |
|
rs2292832
|
GPC1;MIR149;LOC100130449
|
Malignant neoplasm of breast
|
|
0.050 |
GeneticVariation |
BEFREE |
The data showed that the 3746444 GG was associated with increased breast cancer risk (adjusted odds ratio (OR) = 1.71, 95 % confidence interval (CI) = 1.16-2.52) and that rs2292832 CC (adjusted OR = 0.54, 95 % CI = 0.34-0.85) was associated with decreased breast cancer risk.
|
25613069 |
2015 |
|
rs2292832
|
GPC1;MIR149;LOC100130449
|
Malignant neoplasm of breast
|
|
0.050 |
GeneticVariation |
BEFREE |
However, there was no association between rs2292832 (miR-149) polymorphism and BC susceptibility.
|
25483824 |
2015 |
|
rs2292832
|
GPC1;MIR149;LOC100130449
|
Malignant neoplasm of breast
|
|
0.050 |
GeneticVariation |
BEFREE |
However, for the miR-146a rs2910164 (G>C), miR-149 rs2292832 (G>T), miR-373 rs12983273 (C>T), and miR-423 rs6505162 (C>A) polymorphisms, we failed to find any significant association with the risk of breast cancer in any genetic model.
|
23982873 |
2014 |
|
rs2292832
|
GPC1;MIR149;LOC100130449
|
Breast Carcinoma
|
|
0.050 |
GeneticVariation |
BEFREE |
However, for the miR-146a rs2910164 (G>C), miR-149 rs2292832 (G>T), miR-373 rs12983273 (C>T), and miR-423 rs6505162 (C>A) polymorphisms, we failed to find any significant association with the risk of breast cancer in any genetic model.
|
23982873 |
2014 |
|
rs2292832
|
GPC1;MIR149;LOC100130449
|
Breast Carcinoma
|
|
0.050 |
GeneticVariation |
BEFREE |
To explore the relevance of miRNA polymorphisms and female physiological characteristics to breast cancer risk, SNPs located within hsa-miR-605 (rs2043556), hsa-miR-149 (rs2292832), hsa-miR-27a (rs895819), hsa-miR-196a-2 (rs11614913) and hsa-miR-618 (rs2682818) were selected, and their associations with breast cancer risk were analysed.
|
22074121 |
2012 |
|
rs2292832
|
GPC1;MIR149;LOC100130449
|
Malignant neoplasm of breast
|
|
0.050 |
GeneticVariation |
BEFREE |
To explore the relevance of miRNA polymorphisms and female physiological characteristics to breast cancer risk, SNPs located within hsa-miR-605 (rs2043556), hsa-miR-149 (rs2292832), hsa-miR-27a (rs895819), hsa-miR-196a-2 (rs11614913) and hsa-miR-618 (rs2682818) were selected, and their associations with breast cancer risk were analysed.
|
22074121 |
2012 |
|
rs2292832
|
GPC1;MIR149;LOC100130449
|
Malignant neoplasm of stomach
|
|
0.040 |
GeneticVariation |
BEFREE |
This case-control study and meta-analysis confirm that miR-149 gene rs2292832 polymorphism is associated with increased risk of GC among Asians.
|
30274913 |
2018 |
|
rs2292832
|
GPC1;MIR149;LOC100130449
|
Stomach Carcinoma
|
|
0.040 |
GeneticVariation |
BEFREE |
This case-control study and meta-analysis confirm that miR-149 gene rs2292832 polymorphism is associated with increased risk of GC among Asians.
|
30274913 |
2018 |