|
rs2569190
|
CD14;TMCO6
|
Periodontitis
|
|
0.030 |
GeneticVariation |
BEFREE |
Thus, the aim of this study was to evaluate the influence of the <i>TLR4</i> A896G (rs4986790), <i>TLR4</i> C1196T (rs4986791), <i>CD14</i> C-260T (rs2569190), <i>RANKL</i> (<i>TNFSF11</i>, rs2277438), and <i>OPG</i> (<i>TNFSF11B</i> C163T, rs3102735) polymorphisms in periodontitis.
|
31281226 |
2019 |
|
rs2569190
|
CD14;TMCO6
|
Periodontitis
|
|
0.030 |
GeneticVariation |
BEFREE |
The CD14/-260 SNP (rs2569190) served as a control, as a recent meta-analysis suggested no relationship between this SNP and periodontitis.
|
26174031 |
2016 |
|
rs2569190
|
CD14;TMCO6
|
Periodontitis
|
|
0.030 |
GeneticVariation |
BEFREE |
The genetic variation in the CD14 rs2569190 promoter region contributes to the susceptibility of developing periodontitis.
|
28829191 |
2017 |
|
rs2569190
|
CD14;TMCO6
|
Cardiovascular Diseases
|
|
0.020 |
GeneticVariation |
BEFREE |
The SNP rs2569190 significantly contribute to susceptibility and development of cardiovascular disease, particularly in the East Asian population and in the subtype CHD group, in addition, a potential association was observed in the AMI group, T allele acts as a risk factor for cardiovascular disease.
|
30922395 |
2019 |
|
rs2569190
|
CD14;TMCO6
|
Asthma
|
|
0.020 |
GeneticVariation |
BEFREE |
To investigate associations between total serum immunoglobulin E (IgE) levels and single nucleotide polymorphisms (SNPs) from eight candidate genes (IL-4 rs2243250, IL-4Rα rs1805010, IL-13 rs20541, IL-13Rα1 rs2495636, CD14 rs2569190, tumor necrosis factor-alpha (TNF-α) rs1800629, cytotoxic T lymphocyte-associated antigen (CTLA4) rs231775, FCER1B rs1441585) in children with asthma and to evaluate gene-gene interactions.
|
22376040 |
2012 |
|
rs2569190
|
CD14;TMCO6
|
Septicemia
|
|
0.020 |
GeneticVariation |
BEFREE |
The single nucleotide polymorphisms (SNPs) of TLR4 (rs10759932, rs11536889, rs7873784, rs12377632, rs1927907, rs1153879) and CD14 (rs2569190 and rs2563298) in patients with sepsis and control subjects in the Guangxi Province were analyzed by using the polymerase chain reaction-single base extension (PCR-SBE) and DNA sequencing methods.
|
25394369 |
2014 |
|
rs2569190
|
CD14;TMCO6
|
Sepsis
|
|
0.020 |
GeneticVariation |
BEFREE |
The single nucleotide polymorphisms (SNPs) of TLR4 (rs10759932, rs11536889, rs7873784, rs12377632, rs1927907, rs1153879) and CD14 (rs2569190 and rs2563298) in patients with sepsis and control subjects in the Guangxi Province were analyzed by using the polymerase chain reaction-single base extension (PCR-SBE) and DNA sequencing methods.
|
25394369 |
2014 |
|
rs2569190
|
CD14;TMCO6
|
Septicemia
|
|
0.020 |
GeneticVariation |
BEFREE |
In conclusion, CD14 rs2569190 may act as a prognostic variable for the short-term outcome (30-day survival) in patients with sepsis.
|
26020644 |
2015 |
|
rs2569190
|
CD14;TMCO6
|
Asthma
|
|
0.020 |
GeneticVariation |
BEFREE |
The aim of our study was to perform an association analysis of promoter single nucleotide polymorphism (SNP) -159C/T (rs2569190) in the CD14 gene for Slovenian children with asthma.
|
22015088 |
2011 |
|
rs2569190
|
CD14;TMCO6
|
Cardiovascular Diseases
|
|
0.020 |
GeneticVariation |
BEFREE |
The C260T (rs2569190) single-nucleotide polymorphism (SNP) in the promoter region of the CD14 gene was implicated in CVD.
|
19433913 |
2009 |
|
rs2569190
|
CD14;TMCO6
|
Sepsis
|
|
0.020 |
GeneticVariation |
BEFREE |
In conclusion, CD14 rs2569190 may act as a prognostic variable for the short-term outcome (30-day survival) in patients with sepsis.
|
26020644 |
2015 |
|
rs2563298
|
CD14;TMCO6
|
Septicemia
|
|
0.010 |
GeneticVariation |
BEFREE |
The rs11536889 polymorphism in TLR4 and rs2563298 polymorphism in CD14, and two haplotypes were associated with increased susceptibility to sepsis.
|
25394369 |
2014 |
|
rs2563298
|
CD14;TMCO6
|
Hashimoto Disease
|
|
0.010 |
GeneticVariation |
BEFREE |
The study was aimed to determine whether four single nucleotide polymorphisms (rs2915863, rs2569190, rs2569192, and rs2563298) of CD14 are associated with AITDs and its subgroups of GD and HT.
|
30700980 |
2018 |
|
rs2563298
|
CD14;TMCO6
|
Sepsis
|
|
0.010 |
GeneticVariation |
BEFREE |
The rs11536889 polymorphism in TLR4 and rs2563298 polymorphism in CD14, and two haplotypes were associated with increased susceptibility to sepsis.
|
25394369 |
2014 |
|
rs2563298
|
CD14;TMCO6
|
Graves Disease
|
|
0.010 |
GeneticVariation |
BEFREE |
The study was aimed to determine whether four single nucleotide polymorphisms (rs2915863, rs2569190, rs2569192, and rs2563298) of CD14 are associated with AITDs and its subgroups of GD and HT.
|
30700980 |
2018 |
|
rs2569190
|
CD14;TMCO6
|
Traveler's diarrhea
|
|
0.010 |
GeneticVariation |
BEFREE |
Two SNPs in the promoter region of CD14 (-159 C > T; rs2569190 and -4191 C > T; rs5744441) were found to be associated with TD in White visitors.
|
21596674 |
2011 |
|
rs2569190
|
CD14;TMCO6
|
Myocardial Infarction
|
|
0.010 |
GeneticVariation |
BEFREE |
Numerous published studies have investigated the relationship between the CD14-260C>T (rs2569190) polymorphism and the risk of myocardial infarction (MI).
|
31183977 |
2019 |
|
rs2569190
|
CD14;TMCO6
|
Severe Sepsis
|
|
0.010 |
GeneticVariation |
BEFREE |
Genotypes GG of rs2569190 (the CD14 gene) and AT of rs4073 (the IL8 gene) were associated with a significantly increased risk of developing severe sepsis (p = 0.05 and p = 0.01).
|
25000179 |
2014 |
|
rs2569190
|
CD14;TMCO6
|
Allergic sensitization
|
|
0.010 |
GeneticVariation |
BEFREE |
A borderline significant multiplicative interaction was found between E coli and the rs2569190 (CD14/-159) SNP regarding allergic sensitization.
|
20109750 |
2010 |
|
rs2569190
|
CD14;TMCO6
|
Respiratory Tract Infections
|
|
0.010 |
GeneticVariation |
BEFREE |
In children with TT genotype at rs2569190, a higher prenatal intake of vitamins A and C, fruits, and total FV decreased RTI risk (P-trend <0.05), while in infants with TC+CC genotype, a higher prenatal intake of fruit increased RTI risk (P-trend <0.05).
|
27830580 |
2017 |
|
rs2569190
|
CD14;TMCO6
|
Coronary Arteriosclerosis
|
|
0.010 |
GeneticVariation |
BEFREE |
Association of COL4A1 (rs605143, rs565470) and CD14 (rs2569190) genes polymorphism with coronary artery disease.
|
29299748 |
2018 |
|
rs2569190
|
CD14;TMCO6
|
Biliary Atresia
|
|
0.010 |
GeneticVariation |
BEFREE |
We investigated the association of two cis-regulated variants in CD14 (rs2569190) and NOTCH2 (rs835576) with BA susceptibility, using the largest case-control cohort, totaling 506 BA patients and 1,473 healthy controls in a Southern Chinese population.
|
30439647 |
2018 |
|
rs2569190
|
CD14;TMCO6
|
Atopic disorders
|
|
0.010 |
GeneticVariation |
BEFREE |
Our results contradict previous reports that have found a protective effect of the T allele of SNP rs2569190 (C-159T) against atopic disorders.
|
15867866 |
2005 |
|
rs2569190
|
CD14;TMCO6
|
Primary biliary cirrhosis
|
|
0.010 |
GeneticVariation |
BEFREE |
PSC and LTx cohort patients and primary biliary cirrhosis (PBC) control patients were genotyped for the CD14 -260C>T (rs2569190) polymorphism, and genotypes were correlated with long-term clinical outcome.
|
26970220 |
2016 |
|
rs2569190
|
CD14;TMCO6
|
Primary sclerosing cholangitis
|
|
0.010 |
GeneticVariation |
BEFREE |
PSC and LTx cohort patients and primary biliary cirrhosis (PBC) control patients were genotyped for the CD14 -260C>T (rs2569190) polymorphism, and genotypes were correlated with long-term clinical outcome.
|
26970220 |
2016 |