|
cervical cancer
|
|
0.050 |
GeneticVariation
|
BEFREE |
The TNFA-308G/A (rs1800629) and -238G/A (rs361525) polymorphisms are two widely investigated variants for their associations with risk of cervical cancer, but the results are conflicting.
|
21670964 |
2012 |
|
Malignant tumor of cervix
|
|
0.050 |
GeneticVariation
|
BEFREE |
The TNFA-308G/A (rs1800629) and -238G/A (rs361525) polymorphisms are two widely investigated variants for their associations with risk of cervical cancer, but the results are conflicting.
|
21670964 |
2012 |
|
Septicemia
|
|
0.050 |
GeneticVariation
|
BEFREE |
The minor allele frequency of rs1800629 was significantly higher in severe sepsis patients than that in both healthy controls (P(adj) = 0.00046, odds ratio (OR)(adj) = 1.92) and sepsis patients (P(adj) = 0.002, OR(adj) = 1.56).
|
23029405 |
2012 |
|
Cervix carcinoma
|
|
0.050 |
GeneticVariation
|
BEFREE |
There are no significant relationship between rs1800629 polymorphism and high risk HPV infection (OR = 0.649, 95% CI: 0.253-1.670, P = 0.371), cervical cancer (OR = 0.993, 95% CI: 0.376-2.618, P = 0.988), or cervical cancer with HPV infection (OR = 0.663, 95% CI: 0.250-1.758, P = 0.409).
|
23028877 |
2012 |
|
Cervix carcinoma
|
|
0.050 |
GeneticVariation
|
BEFREE |
The TNFA-308G/A (rs1800629) and -238G/A (rs361525) polymorphisms are two widely investigated variants for their associations with risk of cervical cancer, but the results are conflicting.
|
21670964 |
2012 |
|
Malignant tumor of cervix
|
|
0.050 |
GeneticVariation
|
BEFREE |
There are no significant relationship between rs1800629 polymorphism and high risk HPV infection (OR = 0.649, 95% CI: 0.253-1.670, P = 0.371), cervical cancer (OR = 0.993, 95% CI: 0.376-2.618, P = 0.988), or cervical cancer with HPV infection (OR = 0.663, 95% CI: 0.250-1.758, P = 0.409).
|
23028877 |
2012 |
|
cervical cancer
|
|
0.050 |
GeneticVariation
|
BEFREE |
There are no significant relationship between rs1800629 polymorphism and high risk HPV infection (OR = 0.649, 95% CI: 0.253-1.670, P = 0.371), cervical cancer (OR = 0.993, 95% CI: 0.376-2.618, P = 0.988), or cervical cancer with HPV infection (OR = 0.663, 95% CI: 0.250-1.758, P = 0.409).
|
23028877 |
2012 |
|
Septicemia
|
|
0.050 |
GeneticVariation
|
BEFREE |
Carriage of the TNF rs1800629 A allele was associated with higher TNF-alpha serum concentrations on the first day after trauma and during follow-up (two-sided p = 5.0 x 10(-5)), with development of sepsis syndrome (odds ratio 7.14, two-sided p = 1.2 x 10(-6); external validation sample [n = 76]: odds ratio 3.3, one-sided p = .03), and with fatal outcome (odds ratio 7.65, two-sided p = 1.9 x 10(-6)).
|
18434886 |
2008 |
|
Diabetes Mellitus, Insulin-Dependent
|
|
0.040 |
GeneticVariation
|
BEFREE |
Our findings suggest that LTA rs909253 and TNF rs1800629 polymorphisms are associated with the risk of T1D both independently and in combination with polymorphic markers in other inflammatory genes, and the analysis of multi-allelic combinations provides valuable insight in the study of polygenic traits.
|
31054364 |
2019 |
|
Chronic Obstructive Airway Disease
|
|
0.040 |
GeneticVariation
|
BEFREE |
In contrast, the AA genotype carriers of the TNF-α rs1800629 has a significantly higher risk of developing COPD (OR = 1.83, 95%CI: (1.34-2.51), P < 0.00) compared to GG carrier.
|
31260854 |
2019 |
|
Sepsis
|
|
0.040 |
GeneticVariation
|
BEFREE |
Our results suggest that the G/A genotype of <i>TNF-α</i> rs1800629 and rs361525 increases sepsis risk in an Asian population.
|
29340067 |
2017 |
|
Primary malignant neoplasm
|
|
0.040 |
GeneticVariation
|
BEFREE |
Genetic variation of the TNFα rs1800629 might be useful as a biomarker in clinical decision-making since it was found to be related to cancer risk, tumor recurrence, and survival of H&N cancer patients.
|
27997918 |
2017 |
|
Malignant Neoplasms
|
|
0.040 |
GeneticVariation
|
BEFREE |
Genetic variation of the TNFα rs1800629 might be useful as a biomarker in clinical decision-making since it was found to be related to cancer risk, tumor recurrence, and survival of H&N cancer patients.
|
27997918 |
2017 |
|
Stomach Carcinoma
|
|
0.040 |
GeneticVariation
|
BEFREE |
TNF-α-G308A (rs1800629) polymorphisms are associated with gastric cancer in Chinese population.
|
27373488 |
2017 |
|
Chronic Obstructive Airway Disease
|
|
0.040 |
GeneticVariation
|
BEFREE |
The aim of the present work was to investigate the association between the Y113H polymorphism (rs1051740) in EPHX1 gene and -308G/A polymorphism (rs1800629) in TNF-a gene and COPD in Kazakhstan population.
|
28464990 |
2017 |
|
Malignant neoplasm of stomach
|
|
0.040 |
GeneticVariation
|
BEFREE |
TNF-α-G308A (rs1800629) polymorphisms are associated with gastric cancer in Chinese population.
|
27373488 |
2017 |
|
Primary malignant neoplasm
|
|
0.040 |
GeneticVariation
|
BEFREE |
The genotype distribution of SNPs in either rs1800629 or rs361525 did not significantly demonstrate higher frequency in the cancer group (p=0.621 and p=0.68, respectively).
|
27039819 |
2016 |
|
Sepsis
|
|
0.040 |
GeneticVariation
|
BEFREE |
We conducted a cross-sectional study to genotype 415 septic patients and 205 patients without sepsis for the SNPs -308(G/A) rs1800629 of TNF; +252 (G/A) rs909253 of LTA; -511(A/G) rs16944 and +3953(C/T) rs1143634 of IL1B; and -1082(A/G) rs1800896, -819(C/T) rs1800871 and -592(C/A) rs1800872 of IL10.
|
27592234 |
2016 |
|
Malignant Neoplasms
|
|
0.040 |
GeneticVariation
|
BEFREE |
The genotype distribution of SNPs in either rs1800629 or rs361525 did not significantly demonstrate higher frequency in the cancer group (p=0.621 and p=0.68, respectively).
|
27039819 |
2016 |
|
Diabetes Mellitus, Insulin-Dependent
|
|
0.040 |
GeneticVariation
|
BEFREE |
The A allele of rs1800629 was associated with type 1 diabetes (p < 0.001; odds ratio = 0.62).
|
26821796 |
2016 |
|
Malignant neoplasm of stomach
|
|
0.040 |
GeneticVariation
|
BEFREE |
The goal of this study was to evaluate the influence that polymorphisms in the cytokine genes known as TNF-α-308 G/A (rs1800629), TNF-α-857 C/T (rs1799724), IL-8-251 T/A (rs4073), IL-8-845 T/C (rs2227532), and IL-10-592 C/A (rs1800872) have on changes to mRNA expression levels and on the risks of chronic gastritis (CG) and gastric cancer (GC).
|
26088449 |
2015 |
|
Sepsis
|
|
0.040 |
GeneticVariation
|
BEFREE |
In the present study, we aim to investigate the association of promoter-region polymorphisms IL-6 (-174G/C) rs1800795 and TNF-α (-308G/A) rs1800629 with pneumonia-induced sepsis.
|
26025100 |
2015 |
|
Stomach Carcinoma
|
|
0.040 |
GeneticVariation
|
BEFREE |
The goal of this study was to evaluate the influence that polymorphisms in the cytokine genes known as TNF-α-308 G/A (rs1800629), TNF-α-857 C/T (rs1799724), IL-8-251 T/A (rs4073), IL-8-845 T/C (rs2227532), and IL-10-592 C/A (rs1800872) have on changes to mRNA expression levels and on the risks of chronic gastritis (CG) and gastric cancer (GC).
|
26088449 |
2015 |
|
Chronic Obstructive Airway Disease
|
|
0.040 |
GeneticVariation
|
BEFREE |
The single nucleotide polymorphisms found in this region were individually identified; the GA genotypes of rs1800629 (P=0.038, OR =2.07), rs56036015 (P=0.0082, OR =3.18), and rs361525 (P=1.0E-02, OR =4.220) were higher in the COPD group vs the SNC group; after second-stage validation, rs1800629 (P=6.00E-03, OR =2.26) and rs56036015 (P=1.10E-03, OR =2.54) are maintained.
|
26170653 |
2015 |
|
Diabetes Mellitus, Insulin-Dependent
|
|
0.040 |
GeneticVariation
|
BEFREE |
Polymorphisms in the TNF-α(rs1800629), CTLA-4 (rs231775), and PTPN22 (rs2476601) genes have been previous associated with T1D; however, there is no consensus regarding their role in T1D and scarce literature focusing on AIDT and/or CD.
|
26782543 |
2015 |