|
Age related macular degeneration
|
|
0.810 |
GeneticVariation
|
GWASDB |
Seven new loci associated with age-related macular degeneration.
|
23455636 |
2013 |
|
Age related macular degeneration
|
|
0.810 |
GeneticVariation
|
GWASCAT |
Seven new loci associated with age-related macular degeneration.
|
23455636 |
2013 |
|
Age related macular degeneration
|
|
0.810 |
GeneticVariation
|
BEFREE |
Nineteen single nucleotide polymorphisms (SNPs) previously associated with AMD, including rs10490924 (<i>ARMS2/HTRA1</i>), rs10737680 (<i>CFH</i>), rs13278062 (<i>TNFRSF10A</i>), rs1864163 (<i>CETP</i>), rs2230199 (<i>C3</i>), rs3130783 (<i>IER3/DDR1</i>), rs334353 (<i>TGFBR1</i>), rs3812111 (<i>COL10A1</i>), rs429608 (<i>C2/CFB</i>), rs4420638 (<i>APOE</i>), rs4698775 (<i>CFI</i>), rs5749482 (<i>TIMP3</i>), rs6795735 (<i>ADAMTS9</i>), rs8017304 (<i>RAD51B</i>), rs8135665 (<i>SLC16A8</i>), rs920915 (<i>LIPC</i>), rs943080 (<i>VEGFA</i>), rs9542236 (<i>B3GALTL</i>) and rs13081855 (<i>COL8A1/FILIP1L</i>), were genotyped in this cohort.
|
31819893 |
2019 |
|
Alzheimer Disease, Late Onset
|
|
0.010 |
GeneticVariation
|
BEFREE |
SNP rs4420638 on chromosome 19, located 14 kilobase pairs distal to the APOE epsilon variant, significantly distinguished between AD cases and controls (Bonferroni corrected p value = 5.30 x 10(-34), OR = 4.01) and was far more strongly associated with the risk of AD than any other SNP of the 502,627 tested.
|
17474819 |
2007 |
|
Alzheimer's Disease
|
|
0.820 |
GeneticVariation
|
GWASDB |
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
|
21460841 |
2011 |
|
Alzheimer's Disease
|
|
0.820 |
GeneticVariation
|
GWASCAT |
Genome-wide association analysis of age-at-onset in Alzheimer's disease.
|
22005931 |
2012 |
|
Alzheimer's Disease
|
|
0.820 |
GeneticVariation
|
GWASCAT |
A high-density whole-genome association study reveals that APOE is the major susceptibility gene for sporadic late-onset Alzheimer's disease.
|
17474819 |
2007 |
|
Alzheimer's Disease
|
|
0.820 |
GeneticVariation
|
BEFREE |
The SNPs rs2075650 and rs4420638 were linked to the most replications within a single reclassified phenotype or very similar reclassified phenotypes; both were associated with Alzheimer's disease (AD).
|
29942042 |
2019 |
|
Alzheimer's Disease
|
|
0.820 |
GeneticVariation
|
GWASDB |
Sorl1 as an Alzheimer's disease predisposition gene?
|
17975299 |
2008 |
|
Alzheimer's Disease
|
|
0.820 |
GeneticVariation
|
GWASDB |
Candidate single-nucleotide polymorphisms from a genomewide association study of Alzheimer disease.
|
17998437 |
2008 |
|
Alzheimer's Disease
|
|
0.820 |
GeneticVariation
|
GWASCAT |
Sorl1 as an Alzheimer's disease predisposition gene?
|
17975299 |
2008 |
|
Alzheimer's Disease
|
|
0.820 |
GeneticVariation
|
BEFREE |
The minor allele of rs4420638 (G) and the minor allele of rs157582 (T) showed associations with lower Mini-mental State Examination score, higher Alzheimer Disease Assessment Scale-cognitive subscale 11 score and smaller entorhinal volume using both baseline and longitudinal measurements, as well as with accelerated cognitive decline.
|
31760383 |
2019 |
|
Alzheimer's Disease
|
|
0.820 |
GeneticVariation
|
GWASDB |
A high-density whole-genome association study reveals that APOE is the major susceptibility gene for sporadic late-onset Alzheimer's disease.
|
17474819 |
2007 |
|
Alzheimer's Disease
|
|
0.820 |
GeneticVariation
|
GWASCAT |
Genome-wide analysis of genetic predisposition to Alzheimer's disease and related sex disparities.
|
30636644 |
2019 |
|
Alzheimer's Disease
|
|
0.820 |
GeneticVariation
|
GWASDB |
Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease.
|
19734903 |
2009 |
|
Alzheimer's Disease
|
|
0.820 |
GeneticVariation
|
GWASDB |
Genome-wide association study of Alzheimer's disease.
|
22832961 |
2012 |
|
Alzheimer's Disease
|
|
0.820 |
GeneticVariation
|
GWASCAT |
Genome-wide association study of Alzheimer's disease.
|
22832961 |
2012 |
|
Alzheimer's Disease
|
|
0.820 |
GeneticVariation
|
GWASCAT |
Candidate single-nucleotide polymorphisms from a genomewide association study of Alzheimer disease.
|
17998437 |
2008 |
|
Alzheimer's Disease
|
|
0.820 |
GeneticVariation
|
GWASCAT |
Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
|
26830138 |
2016 |
|
Alzheimer's Disease
|
|
0.820 |
GeneticVariation
|
GWASDB |
Genome-wide association analysis of age-at-onset in Alzheimer's disease.
|
22005931 |
2012 |
|
Atrial Fibrillation
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.
|
27790247 |
2016 |
|
Body mass index
|
|
0.700 |
GeneticVariation
|
GWASCAT |
The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.
|
26426971 |
2015 |
|
Body mass index
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.
|
27790247 |
2016 |
|
Body mass index procedure
|
|
0.700 |
GeneticVariation
|
GWASCAT |
The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.
|
26426971 |
2015 |
|
C-reactive protein measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels.
|
21300955 |
2011 |