rs4420638, APOC1

N. diseases: 43
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.720 GeneticVariation GWASCAT A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease. 26343387 2015
Longevity
CUI: C0023980
Disease: Longevity
0.800 GeneticVariation GWASDB A genome-wide association study confirms APOE as the major gene influencing survival in long-lived individuals. 21740922 2011
Longevity
CUI: C0023980
Disease: Longevity
0.800 GeneticVariation GWASCAT A genome-wide association study confirms APOE as the major gene influencing survival in long-lived individuals. 21740922 2011
Mental deterioration
CUI: C0234985
Disease: Mental deterioration
0.710 GeneticVariation GWASDB A genome-wide scan for common variants affecting the rate of age-related cognitive decline. 22054870 2012
Psychomotor Performance
CUI: C0033923
Disease: Psychomotor Performance
0.700 GeneticVariation GWASCAT A genome-wide scan for common variants affecting the rate of age-related cognitive decline. 22054870 2012
Alzheimer's Disease
CUI: C0002395
Disease: Alzheimer's Disease
0.820 GeneticVariation GWASCAT A high-density whole-genome association study reveals that APOE is the major susceptibility gene for sporadic late-onset Alzheimer's disease. 17474819 2007
Alzheimer's Disease
CUI: C0002395
Disease: Alzheimer's Disease
0.820 GeneticVariation GWASDB A high-density whole-genome association study reveals that APOE is the major susceptibility gene for sporadic late-onset Alzheimer's disease. 17474819 2007
Low density lipoprotein cholesterol measurement
CUI: C0202117
Disease: Low density lipoprotein cholesterol measurement
0.800 GeneticVariation GWASCAT A large electronic-health-record-based genome-wide study of serum lipids. 29507422 2018
High density lipoprotein measurement
CUI: C0392885
Disease: High density lipoprotein measurement
0.800 GeneticVariation GWASCAT A large electronic-health-record-based genome-wide study of serum lipids. 29507422 2018
Serum total cholesterol measurement
CUI: C1445957
Disease: Serum total cholesterol measurement
0.800 GeneticVariation GWASCAT A large electronic-health-record-based genome-wide study of serum lipids. 29507422 2018
Triglycerides measurement
CUI: C0202236
Disease: Triglycerides measurement
0.800 GeneticVariation GWASCAT A large electronic-health-record-based genome-wide study of serum lipids. 29507422 2018
Rheumatoid Arthritis
CUI: C0003873
Disease: Rheumatoid Arthritis
0.010 GeneticVariation BEFREE Among them, 2 SNP, rs688 and rs4420638, were more prevalent in patients with RA than in controls. 23588940 2013
C-reactive protein measurement
CUI: C0201657
Disease: C-reactive protein measurement
0.800 GeneticVariation GWASDB Are C-reactive protein associated genetic variants associated with serum levels and retinal markers of microvascular pathology in Asian populations from Singapore? 23844046 2013
High density lipoprotein measurement
CUI: C0392885
Disease: High density lipoprotein measurement
0.800 GeneticVariation GWASCAT Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels. 28334899 2017
Waist-Hip Ratio
CUI: C0205682
Disease: Waist-Hip Ratio
0.700 GeneticVariation GWASCAT Association of Genetic Variants Related to Gluteofemoral vs Abdominal Fat Distribution With Type 2 Diabetes, Coronary Disease, and Cardiovascular Risk Factors. 30575882 2018
Low density lipoprotein cholesterol measurement
CUI: C0202117
Disease: Low density lipoprotein cholesterol measurement
0.800 GeneticVariation GWASCAT Biological, clinical and population relevance of 95 loci for blood lipids. 20686565 2010
Low density lipoprotein cholesterol measurement
CUI: C0202117
Disease: Low density lipoprotein cholesterol measurement
0.800 GeneticVariation GWASDB Biological, clinical and population relevance of 95 loci for blood lipids. 20686565 2010
Serum total cholesterol measurement
CUI: C1445957
Disease: Serum total cholesterol measurement
0.800 GeneticVariation GWASDB Biological, clinical and population relevance of 95 loci for blood lipids. 20686565 2010
High density lipoprotein measurement
CUI: C0392885
Disease: High density lipoprotein measurement
0.800 GeneticVariation GWASDB Biological, clinical and population relevance of 95 loci for blood lipids. 20686565 2010
Serum total cholesterol measurement
CUI: C1445957
Disease: Serum total cholesterol measurement
0.800 GeneticVariation GWASCAT Biological, clinical and population relevance of 95 loci for blood lipids. 20686565 2010
High density lipoprotein measurement
CUI: C0392885
Disease: High density lipoprotein measurement
0.800 GeneticVariation GWASCAT Biological, clinical and population relevance of 95 loci for blood lipids. 20686565 2010
Serum LDL cholesterol measurement
CUI: C0428474
Disease: Serum LDL cholesterol measurement
0.700 GeneticVariation GWASDB Biological, clinical and population relevance of 95 loci for blood lipids. 20686565 2010
Serum HDL cholesterol measurement
CUI: C0428472
Disease: Serum HDL cholesterol measurement
0.700 GeneticVariation GWASDB Biological, clinical and population relevance of 95 loci for blood lipids. 20686565 2010
Serum total cholesterol measurement
CUI: C1445957
Disease: Serum total cholesterol measurement
0.800 GeneticVariation GWASCAT Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation. 27286809 2016
Low density lipoprotein cholesterol measurement
CUI: C0202117
Disease: Low density lipoprotein cholesterol measurement
0.800 GeneticVariation GWASCAT Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation. 27286809 2016