Source: ANIMAL_MODELS

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962 42
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885 62
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923 86
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962 12
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962 76
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885 45
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962 94
IL17A Q16552 interleukin 17A 4.3E-02 0.324 0.923 27
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923 47
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923 58
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885 48
CAT P04040 catalase Enzyme 1.6E-10 0.359 0.962 41
IL18 Q14116 interleukin 18 3.1E-02 0.365 0.923 41
FAS P25445 Fas cell surface death receptor 0.81 0.372 0.923 49
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885 72
KDR P35968 kinase insert domain receptor Kinase 1.00 0.378 0.885 20
CXCL10 P02778 C-X-C motif chemokine ligand 10 Signaling 0.37 0.378 0.885 11
CXCL12 P48061 C-X-C motif chemokine ligand 12 0.12 0.379 0.846 9
EDN1 P05305 endothelin 1 Signaling 0.46 0.380 0.846 48
HMOX1 P09601 heme oxygenase 1 9.7E-03 0.381 0.923 71
PCNA P12004 proliferating cell nuclear antigen Nucleic acid binding 0.98 0.382 0.846 17
S100B P04271 S100 calcium binding protein B Calcium-binding protein 4.4E-02 0.383 0.923 23
CAV1 Q03135 caveolin 1 Enzyme modulator 8.3E-03 0.388 0.885 22
LGALS3 P17931 galectin 3 Signaling 2.3E-05 0.392 0.846 15