Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
ALOX15 P16050 arachidonate 15-lipoxygenase Enzyme 1.1E-23 0.502 0.846 4
MMP13 P45452 matrix metallopeptidase 13 Enzyme 7.9E-18 0.452 0.923 17
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923 86
AGER Q15109 advanced glycosylation end-product specific receptor Receptor 6.4E-16 0.420 0.885 43
FGA P02671 fibrinogen alpha chain 1.2E-13 0.573 0.769 14
PPP1R15A O75807 protein phosphatase 1 regulatory subunit 15A 2.2E-12 0.608 0.692 5
CAST P20810 calpastatin 4.1E-12 0.541 0.846 7
GC P02774 GC vitamin D binding protein Transporter 2.7E-11 0.489 0.885 8
CTSB P07858 cathepsin B Enzyme 5.9E-11 0.457 0.846 22
OPRM1 P35372 opioid receptor mu 1 G-protein coupled receptor 7.9E-11 0.457 0.808 8
CAT P04040 catalase Enzyme 1.6E-10 0.359 0.962 41
DBH P09172 dopamine beta-hydroxylase 3.3E-10 0.511 0.846 8
CP P00450 ceruloplasmin Enzyme 4.2E-10 0.466 0.846 10
CCR5 P51681 C-C motif chemokine receptor 5 (gene/pseudogene) G-protein coupled receptor 4.3E-10 0.398 0.885 26
PTGIS Q16647 prostaglandin I2 synthase 1.2E-09 0.617 0.654 2
IRAK4 Q9NWZ3 interleukin 1 receptor associated kinase 4 Kinase 7.8E-09 0.578 0.769 2
ESR2 Q92731 estrogen receptor 2 Nuclear receptor 4.5E-08 0.400 0.923 25
CTSC P53634 cathepsin C Enzyme 1.1E-07 0.541 0.731 6
ANXA1 P04083 annexin A1 1.2E-07 0.442 0.885 30
APEX1 P27695 apurinic/apyrimidinic endodeoxyribonuclease 1 1.9E-07 0.458 0.846 7
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885 72
ALOX5 P09917 arachidonate 5-lipoxygenase Enzyme 1.2E-06 0.447 0.885 14
NES P48681 nestin 1.6E-06 0.450 0.808 5
TH P07101 tyrosine hydroxylase 1.7E-06 0.462 0.885 18